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Solute Carrier Family 30, Member 10 Proteins (SLC30A10)

SLC30A10 is highly expressed in the liver and is inducible by manganese. Additionally we are shipping SLC30A10 Antibodies (21) and SLC30A10 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC30A10 55532 Q6XR72
Mouse SLC30A10 SLC30A10 226781 Q3UVU3
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Top SLC30A10 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

SLC30A10 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Solute Carrier Family 30, Member 10 (SLC30A10) Interaction Partners

Human Solute Carrier Family 30, Member 10 (SLC30A10) interaction partners

  1. We describe early disease manifestations (including videos) in 5 previously unreported Indian children, carrying novel homozygous SLC30A10 mutation

  2. SLC30A10 is a cell surface-localized manganese efflux transporter that reduces manganese levels and protects against manganese toxicity.

  3. These results suggest that both the up-regulation of ZIP14 (show SLC39A14 Proteins) and the down-regulation of ZnT10 by IL-6 (show IL6 Proteins) might have enhanced the accumulation of manganese in SH-SY5Y cells.

  4. a case of inherited manganism caused by SLC30A10 mutation is presented

  5. ZnT10 is significantly decreased in the frontal cortex in Alzheimer's disease.

  6. This review will address Mn transport proteins, the newly discovered SLC30A10 mutations and their implications to Parkinsonism and Mn regulation.

  7. The study demonstrates down-regulation by Zn of ZnT10 mRNA levels in cultured intestinal and neuroblastoma cell lines and demonstrate reduced transcription from the ZnT10 promoter at an elevated extracellular Zn concentration.

  8. SLC30A10 mutations cause a treatable recessive disease with pleomorphic phenotype, and provide compelling evidence that SLC30A10 plays a pivotal role in manganese transport.

  9. This work has confirmed that SLC30A10 functions as a Mn transporter in humans that, when defective, causes Mn accumulation in liver and brain.

  10. identified the full-length sequences of SLC30A10, extending the SLC30 family to ten members; used an expressed sequence tag (EST (show MAP3K8 Proteins)) data mining strategy to determine the pattern of ZnT genes expression in tissues

SLC30A10 Protein Profile

Protein Summary

This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene.

Gene names and symbols associated with SLC30A10

  • solute carrier family 30, member 10 (SLC30A10)
  • solute carrier family 30, member 10 (Slc30a10)
  • E130106K10Rik protein
  • Gm212 protein
  • HMDPC protein
  • ZnT-10 protein
  • ZNT8 protein
  • ZNT10 protein
  • ZRC1 protein

Protein level used designations for SLC30A10

zinc transporter 10 , zinc transporter 8 , znT-10

GENE ID SPECIES
55532 Homo sapiens
226781 Mus musculus
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