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Band 3/AE1 Proteins

(Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) (SLC4A1))
The protein encoded by this gene is part of the anion exchanger (AE) family and is expressed in the erythrocyte plasma membrane, where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. The protein comprises two domains that are structurally and functionally distinct. The N-terminal 40kDa domain is located in the cytoplasm and acts as an attachment site for the red cell skeleton by binding ankyrin. The glycosylated C-terminal membrane-associated domain contains 12-14 membrane spanning segments and carries out the stilbene disulphonate-sensitive exchange transport of anions. The cytoplasmic tail at the extreme C-terminus of the membrane domain binds carbonic anhydrase II. The encoded protein associates with the red cell membrane protein glycophorin A and this association promotes the correct folding and translocation of the exchanger. This protein is predominantly dimeric but forms tetramers in the presence of ankyrin. Many mutations in this gene are known in man, and these mutations can lead to two types of disease: destabilization of red cell membrane leading to hereditary spherocytosis, and defective kidney acid secretion leading to distal renal tubular acidosis. Other mutations that do not give rise to disease result in novel blood group antigens, which form the Diego blood group system. Southeast Asian ovalocytosis (SAO, Melanesian ovalocytosis) results from the heterozygous presence of a deletion in the encoded protein and is common in areas where Plasmodium falciparum malaria is endemic. One null mutation in this gene is known, resulting in very severe anemia and nephrocalcinosis. [provided by RefSeq, Jul 2008].
Band 3/AE1 Protein (AA 1-403) (His tag) Band 3/AE1 Protein (AA 1-403) (His tag) Band 3/AE1 Protein (AA 1-403) (His tag) (ABIN7125166)

SLC4A1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

Band 3/AE1 Protein (AA 261-360) (GST tag) Band 3/AE1 Protein (AA 261-360) (GST tag) Band 3/AE1 Protein (AA 261-360) (GST tag) (ABIN1320468)

SLC4A1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Band 3/AE1 Protein (ABIN7199706)

SLC4A1 Origin: Human Host: Wheat germ Recombinant AP

Band 3/AE1 Proteins by Origin

Find Band 3/AE1 Proteins for a variety of species such as anti-Human Band 3/AE1, anti-Rat Band 3/AE1, anti-Mouse Band 3/AE1. The species listed below are among those available. Click on a link to go to the corresponding products.

Band 3/AE1 Proteins by Source

Here you will find Band 3/AE1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Band 3/AE1 Proteins by Protein Type

Here you can find Band 3/AE1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Band 3/AE1 Proteins by Application

Find Band 3/AE1 Proteins validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Band 3/AE1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125166
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320468
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN7199706
Quantity 2 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417276
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413748
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421890
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3111692
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3132502
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2713525
Quantity 20 μg
Datasheet Datasheet

Aliases for Band 3/AE1 Proteins

solute carrier family 4 member 1 (Diego blood group) (SLC4A1) Proteins
solute carrier family 4 (anion exchanger), member 1 (Slc4a1) Proteins
solute carrier family 4 (anion exchanger), member 1a (Diego blood group) (slc4a1a) Proteins
Band 3 (LOC100136769) Proteins
erythrocyte membrane protein band 4.1 like 3 (EPB41L3) Proteins
solute carrier family 4 member 1 (Diego blood group) L homeolog (slc4a1.L) Proteins
solute carrier family 4 member 1 (SLC4A1) Proteins
solute carrier family 4 member 1 (Diego blood group) (slc4a1) Proteins
solute carrier family 4 member 1 (Slc4a1) Proteins
AE1 Proteins
Ae1 Proteins
ae1 Proteins
band3 Proteins
BB3 Proteins
BND3 Proteins
bnd3 Proteins
CD233 Proteins
cd233 Proteins
DI Proteins
EAT Proteins
EMPB3 Proteins
Empb3 Proteins
empb3 Proteins
EPB3 Proteins
epb3 Proteins
FR Proteins
l11Jus51 Proteins
LOC100136769 Proteins
MGC80391 Proteins
MGC152771 Proteins
RTA1A Proteins
rta1a Proteins
si:dz180g5.1 Proteins
slc4a1 Proteins
SLC4A1 Proteins
SW Proteins
WD Proteins
WD1 Proteins
wd1 Proteins
WR Proteins
zgc:111889 Proteins
zgc:152771 Proteins
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