anti-Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) (SLC4A1) Antibodies

The protein encoded by SLC4A1 is part of the anion exchanger (AE) family and is expressed in the erythrocyte plasma membrane, where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. Additionally we are shipping Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC4A1 6521 P02730
SLC4A1 20533 P04919
SLC4A1 24779 P23562
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Top anti-Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) Antibodies at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Horse Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p), WB Anti- Band 3 Picoband antibody,IHC(P) IHC(P): Rat Kidney Tissue Anti- Band 3 Picoband antibody, Western blotting All lanes: Anti Band 3  at 0.5ug/ml Lane 1: Rat Brain Tissue Lysate at 50ug Lane 2: Rat Kidney Tissue Lysate at 50ug Lane 3: Rat Liver Tissue Lysate at 50ug Lane 4: Rat Spleen Tissue Lysate at 50ug Lane 5: Human Placenta Tissue Lysate at 50ug Predicted bind size: 102KD Observed bind size: 102KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC (p), WB Spleen 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of SLC4A1 expression in transfected 293T cell line by SLC4A1 MaxPab polyclonal antibody.Lane 1: SLC4A1 transfected lysate(100.21 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Placenta, Erythrocytes (formalin-fixed, paraffin-embedded) stained with SLC4A1 antibody ABIN290275 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   50 μg Log in to see 10 to 12 Days
$462.00
Details
Human Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 13 to 16 Days
$332.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.05 mg Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IHC (p) Immunochemical staining of human SLC4A1 in human placenta with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections). Immunochemical staining of human SLC4A1 in human kidney with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Log in to see 20 to 21 Days
$218.90
Details

SLC4A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
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Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) Antibodies

  1. Human Polyclonal SLC4A1 Primary Antibody for WB - ABIN520240 : Govekar, Kawle, Thomas, Advani, Pv, Zingde: Eryptotic phenotype in chronic myeloid leukemia: contribution of neutrophilic cathepsin g. in Anemia 2012 (PubMed)

  2. Horse (Equine) Polyclonal SLC4A1 Primary Antibody for WB - ABIN2778128 : Kittanakom, Cordat, Akkarapatumwong, Yenchitsomanus, Reithmeier: Trafficking defects of a novel autosomal recessive distal renal tubular acidosis mutant (S773P) of the human kidney anion exchanger (kAE1). in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) Interaction Partners

Human Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) (SLC4A1) interaction partners

  1. These results suggested the possible involvement of Band3 in the transport of Sphingosine 1-phosphate, a multi-functional bioactive phospholipid, from erythrocytes.

  2. the results of the present study suggest that the diffuse expression of AE1 is related to a worse prognosis in patients with advanced esophageal squamous cell carcinoma, and that it regulates tumor progression by affecting MAPK (show MAPK1 Antibodies) and Hedgehog (show SHH Antibodies) signaling pathways. These results provide an insight into the role of AE1 as a mediator of and/or a biomarker for esophageal squamous cell carcinoma.

  3. study reports the R589H mutation in SLC4A1 gene in families with hereditary distal renal tubular acidosis for the first time in China

  4. Forced FOG1 (show ZFPM1 Antibodies) protein expression in K562 erythroleukemia cells induced the expression of SLC4A1 protein, but repressed that of transcription factor PU.1.

  5. Nonsense mutation in exon 12 of SLC4A1 gene is associated with severe hemolytic anemia, dyserythropoiesis and complete distal renal tubular acidosis.

  6. While weak interactions between glycophorin and band 3 undoubtedly exist, glycophorin A (show GYPA Antibodies) and band 3 must have separate interactions in the membrane that control their lateral mobility.

  7. three merozoite proteins (PvTRAg36, PvATRAg74, and PvTRAg38) of this family interact with Band 3 on human erythrocytes through its three exofacial loops.

  8. with exacerbation of the oxidative stress during vaso-occlusive crises in sickle cell anaemia patients, the higher concentration of harmful circulating RBC (show CACNA1C Antibodies)-derived microparticles and the reduced anti-band 3 autoantibodies levels may be both related to the recruitment of oxidized band 3 into membrane aggregates.

  9. We propose that, in polarized renal epithelial cells, the apically mistargeted kAE1 (show OSGEP Antibodies) R901X mutant is endocytosed faster than kAE1 (show OSGEP Antibodies) WT and its recycling to the basolateral membrane is delayed. This resets the equilibrium, such that kAE1 (show OSGEP Antibodies) R901X resides predominantly in an endomembrane compartment, thereby likely participating in development of dRTA disease.

  10. The conformational dynamics of signal-anchor transmembrane segment 1 of SLC4A1 protein of the Southeast Asian ovalocytosis red blood cells has been reported.

Mouse (Murine) Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) (SLC4A1) interaction partners

  1. properties are controlled by the O2-dependent association of hemoglobin (show HBB Antibodies) with band 3

  2. NH4Cl loading elicited adaptive doubling of AE1 mRNA in GPR4 (show GPR4 Antibodies)+/+, but a 50% less pronounced response in GPR4 (show GPR4 Antibodies)-/-.

  3. Activities of AE1 and the sodium pump are coregulated in kidney.

  4. AE1 is enhanced by acidosis, NaCl, and the combination of DOCA and NaHCO3 in renal collecting ducts.

  5. These findings indicate that the conserved YXXPhi sequence or a noncanonical YXXXPhi sequence in the N-terminal region facilitates the endocytic recycling of erythroid AE1 through a clathrin-mediated pathway.

  6. These results suggest that AE1 is potentially a key therapeutic target and the silencing of AE1 expression in gastric mucosa could provide a new therapeutic approach for treating gastric cancer.

  7. These results demonstrate that mammalian erythroblast enucleation does not depend on the membrane integrity generated by the ankyrin-band 3 complex.

  8. Data suggest that glycophorin A (Gpa (show GYPA Antibodies)) increases expression and activity of Cl-/HCO3- exchanger Ae1, that G719D mutation renders Ae1 mutant constructs GPA (show GYPA Antibodies)-unresponsive, and suggests a role for Ae1 amino acids 22-28 in GPA (show GYPA Antibodies) responsiveness.

  9. podocyte protein kidney anion exchanger 1 interacts with nephrin (show NPHS1 Antibodies) and kinase to maintain the structure and function of the glomerular basement membrane.

  10. This review explores what is known about the erythrocyte membrane protein band 3 complexes of mice and humans, focussing on the observed species differences and their potential functional consequences.

Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) (SLC4A1) Antigen Profile

Protein Summary

The protein encoded by this gene is part of the anion exchanger (AE) family and is expressed in the erythrocyte plasma membrane, where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. The protein comprises two domains that are structurally and functionally distinct. The N-terminal 40kDa domain is located in the cytoplasm and acts as an attachment site for the red cell skeleton by binding ankyrin. The glycosylated C-terminal membrane-associated domain contains 12-14 membrane spanning segments and carries out the stilbene disulphonate-sensitive exchange transport of anions. The cytoplasmic tail at the extreme C-terminus of the membrane domain binds carbonic anhydrase II. The encoded protein associates with the red cell membrane protein glycophorin A and this association promotes the correct folding and translocation of the exchanger. This protein is predominantly dimeric but forms tetramers in the presence of ankyrin. Many mutations in this gene are known in man, and these mutations can lead to two types of disease: destabilization of red cell membrane leading to hereditary spherocytosis, and defective kidney acid secretion leading to distal renal tubular acidosis. Other mutations that do not give rise to disease result in novel blood group antigens, which form the Diego blood group system. Southeast Asian ovalocytosis (SAO, Melanesian ovalocytosis) results from the heterozygous presence of a deletion in the encoded protein and is common in areas where Plasmodium falciparum malaria is endemic. One null mutation in this gene is known, resulting in very severe anemia and nephrocalcinosis.

Gene names and symbols associated with SLC4A1

  • solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) (SLC4A1) antibody
  • solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) (slc4a1) antibody
  • Band 3 (LOC100136769) antibody
  • solute carrier family 4 (anion exchanger), member 1 (SLC4A1) antibody
  • solute carrier family 4 (anion exchanger), member 1 (Slc4a1) antibody
  • solute carrier family 4, anion exchanger, member 1 (SLC4A1) antibody
  • Ae1 antibody
  • BND3 antibody
  • CD233 antibody
  • DI antibody
  • EAT antibody
  • Empb3 antibody
  • EPB3 antibody
  • FR antibody
  • l11Jus51 antibody
  • LOC100136769 antibody
  • MGC80391 antibody
  • RTA1A antibody
  • slc4a1 antibody
  • SW antibody
  • WD antibody
  • WD1 antibody
  • WR antibody

Protein level used designations for SLC4A1

solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) , erythroid anion exchanger 1 , band 3 anion transport protein , solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3) , Band 3 , band 3 anion transport protein-like , Diego blood group , Froese blood group , Swann blood group , Waldner blood group , Wright blood group , anion exchange protein 1 , anion exchanger 1 , anion exchanger-1 , erythrocyte membrane protein band 3 , erythroid anion exchange protein , solute carrier family 4, anion exchanger, number 1 , AE 1 , MEB3 , solute carrier family 4 member 1 , Solute carrier family 4, member 1, anion exchange protein 1 (kidney band 3) , erythrocyte anion transport protein

GENE ID SPECIES
395371 Gallus gallus
443978 Xenopus laevis
454727 Pan troglodytes
100009691 Equus caballus
100136769 Oncorhynchus mykiss
100174401 Pongo abelii
100349024 Oryctolagus cuniculus
100483431 Ailuropoda melanoleuca
100486998 Xenopus (Silurana) tropicalis
100514249 Sus scrofa
490939 Canis lupus familiaris
100563543 Anolis carolinensis
100579389 Nomascus leucogenys
6521 Homo sapiens
20533 Mus musculus
24779 Rattus norvegicus
396532 Gallus gallus
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