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SLC5A1 encodes a member of the sodium-dependent glucose transporter (SGLT) family. Additionally we are shipping Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Kits (28) and Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Proteins (4) and many more products for this protein.
Showing 10 out of 114 products:
Dog (Canine) Polyclonal SLC5A1 Primary Antibody for IF (p), IHC (p) - ABIN738066
Chen, Ma, Huang, Zhang, Zhong, Han, Hu, Li: Efficiency of transcellular transport and efflux of flavonoids with different glycosidic units from flavonoids of Litsea coreana L. in a MDCK epithelial cell monolayer model. in European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2014
Rat (Rattus) Polyclonal SLC5A1 Primary Antibody for ELISA, IHC - ABIN4353209
Hummel, Lu, Loo, Hirayama, Voss, Wright: Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2. in American journal of physiology. Cell physiology 2010
SGLT1 expression is enhanced, with time, 2-fold in the duodenum and 3.3-fold in the ileum for horses switched, gradually over a 2-month period, from low (<1.0 g/kg bwt/day) to high hCHO (6.0 g/kg bwt/day) diets of known composition.
Homoeriodictyol affects both the glucose metabolism and the serotonin system in Caco-2 cells via a sodium glucose cotransporter 1 protein (SGLT-1)-meditated pathway.
Binding of RS1 (show RS1 Antibodies)-Reg (show EXTL3 Antibodies) to ODC1 (show ODC1 Antibodies) inhibits the enzymatic activity at low intracellular glucose, which is blunted at high intracellular glucose.
JAK3 (show JAK3 Antibodies) up-regulates SGLT1 activity by increasing the carrier protein abundance in the cell membrane, an effect enforcing cellular glucose uptake into activated lymphocytes and thus contributing to the immune response.
Results found that SGLT1 is required for FLIPL induced cell aerobic glycolysis and survival to low glucose conditions. In patients with hepatocellular carcinoma, SGLT1 expression level was positively correlated with FLIPL expression level.
Although the similarity between the pf values of SGLT1 and aquaporin-1 (show AQP1 Antibodies) makes a transcellular pathway plausible, it renders water pumping physiologically negligible because the passive flux would be orders of magnitude larger.
Compound K induces SGLT1 expression and glucose uptake in differentiated intestinal Caco-2 cells.
Data demonstrate a role for Per1 (show PER1 Antibodies) in the transcriptional regulation of NHE3 (show SLC9A3 Antibodies) and SGLT1 in the kidney.
Cardiac SGLTs, possibly SGLT1 in particular, appear to provide an important protective mechanism against ischemia-reperfusion injury by replenishing ATP stores in ischemic cardiac tissues.
CREB (show CREB1 Antibodies) activation is essential for EGF (show EGF Antibodies)-induced SGLT1 gene expression.
SGLT1 or GLUT2 (show SLC2A2 Antibodies) interact with the cytoskeleton in the intestinal epithelium during hexose absorption.
sodium influx through cerebral SGLT-1 may exacerbate cerebral ischemia-induced neuronal damage
Enhanced cerebral sodium-glucose transporter function mediated by post-ischemic hyperglycemia exacerbates the development of cerebral ischemic neuronal damage.
These findings support the involvement of SGLT1 in post-oral glucose and MDG (show CACNA1S Antibodies) conditioning.
Compound K upregulates SGLT1 expression in vivo in mice.
Studied leptin (show LEP Antibodies) and CST (show CORT Antibodies) modulation of SGLT1 expression in hyperleptinemic type 2 diabetic mice.
Cardiac knockdown of SGLT1 in a murine model of PRKAG2 (show PRKAG2 Antibodies) cardiomyopathy attenuates the disease phenotype, implicating SGLT1 in the pathogenesis. Overexpression of SGLT1 causes pathologic cardiac hypertrophy and left ventricular failure that is reversible.
In conclusion, SPAK (show STK39 Antibodies) is a powerful negative regulator of SGLT1 protein abundance in the cell membrane and thus of electrogenic glucose transport.
role of SGLT1 and GLUT2 (show SLC2A2 Antibodies) in intestinal glucose transport and sensing
Improved glycemic control in mice lacking Sglt1 and Sglt2 (show SLC5A2 Antibodies).
the effects of Transmissible gastroenteritis virus infection on glucose uptake and SGLT1 and GLUT2 (show SLC2A2 Antibodies) expression, are reported.
Feed intake remains low whereas respiratory frequency and body temperature remain higher and expression of HSP90 (show HSP90 Antibodies), CAT1 (show SLC7A1 Antibodies), SGLT1 and GLUT4 (show SLC2A4 Antibodies) increases in some tissues in pigs under chronic heat stress conditions.
The segmental differences in porcine glucose transport characteristics may be based on direct or indirect modulations of SGLT1 activity.
The increased expression of SGLT1 in the jejunum by phytase supplementation implies that phytase alleviated the negative effects of phytic acid partly through increased expression of SGLT1.
neonates have high intestinal apical SGLT1 uptake activity by abundantly expressing SGLT1 protein in epithelia and on apical membrane along the entire crypt-villus axis in association with enhanced protein translational control mechanisms in crypt cells.
In accord with a rise in methyl alpha-D-glucopyranoside uptake activity, the mRNA and protein levels of SGLT1 were apparently up-regulated in the presence of apoE3
Expression of SLGT1 was evaluated in LLC-PK1 cells grown on porous membranes for the development of an artificial kidney.
Na+-dependent glucose cotransporter(SGLT)1 mRNA was most abundant in bovine intestine, at intermediate levels in bovine kidney, and at lower levels in bovine mammary gland, liver, and lung.
This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene.
, sodium/glucose cotransporter 1
, solute carrier family 5 (sodium/glucose cotransporter), member 1
, solute carrier family 5, member 1
, sodium/glucose cotransporter 1-like
, Na+/glucose cotransporter 1
, high affinity sodium-glucose cotransporter
, Na(+)/glucose cotransporter 1
, sodium glucose cotransporter 1
, sodium-glucose cotransporter 1
, solute carrier family 5 member 1
, solute carrier family 5, member alpha 1
, Na+/glucose cotransporter
, Solute carrier family 5, member alpha 1 (Na+/glucose cotransporter)
, sodium-glucose cotransporter-like 1
, cortical sodium-D-glucose cotransporter
, sodium/glucose cotransporter-like protein
, Na(+)/glucose cotransporter 5
, sodium/glucose cotransporter 5
, solute carrier family 5 member 10