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SORCS3 encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. Additionally we are shipping SORCS3 Antibodies (22) and SORCS3 Kits (1) and many more products for this protein.
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The propeptide is not a requirement for normal processing of the receptor and does not prevent ligands from binding to the SorCS3 precursor form
Study demonstrates that SorCS3 expression is restricted to the developing and adult nervous system
Sortilin-related receptor (show SORL1 Proteins) SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction.
SorCS3 and the homologous sorCS1 (show SORCS1 Proteins) and sorCS2 (show SORCS2 Proteins) genes were expressed in a combinatorial mostly non-overlapping pattern in the developing and mature central nervous system; activity-dependent induction of sorCS3 did not require protein synthesis
This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain\; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins\; it is not yet known if this encoded protein is also a preproprotein.
sortilin-related VPS10 domain containing receptor 3
, VPS10 domain receptor protein SORCS 3
, VPS10 domain-containing receptor SorCS3-like
, VPS10 domain-containing receptor SorCS3
, VPS10 domain receptor protein SORCS 3 (SORCS3)