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Sp8 Transcription Factor Proteins (SP8)

The protein encoded by SP8 is an SP family transcription factor that in mouse has been shown to be essential for proper limb development. Additionally we are shipping SP8 Antibodies (22) and SP8 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SP8 221833 Q8IXZ3
SP8 320145 Q8BMJ8
SP8    
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Top SP8 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,356.83
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,417.33
Details

SP8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

Chicken

More Proteins for Sp8 Transcription Factor (SP8) Interaction Partners

Human Sp8 Transcription Factor (SP8) interaction partners

  1. Data suggest expression of transcription factor p8/SP8 is up-regulated in endoplasmic reticulum stress due to lipotoxicity; overexpression of SP8 up-regulates autophagy; autophagy due to lipotoxicity requires SP8; these reactions are mTOR (show FRAP1 Proteins)-independent.

  2. Genetic variants on 3q21 and in the Sp8 transcription factor gene (SP8) as susceptibility loci for psychotic disorders.

  3. This study provided that SP8 are associated with Bipolar I in the Han Chinese population

Mouse (Murine) Sp8 Transcription Factor (SP8) interaction partners

  1. Sp5 (show SP5 Proteins)/8 bind directly to GC boxes in Wnt (show WNT2 Proteins) target gene enhancers and to adjacent, or distally positioned, chromatin-bound T-cell factor (Tcf) 1 (show HNF1A Proteins)/lymphoid enhancer factor (Lef) 1 (show LEF1 Proteins) to facilitate recruitment of beta-catenin (show CTNNB1 Proteins) to target gene enhancers.

  2. Provide the first direct evidence that a transient Sp8+ interneuron handlebar-like structure exists in the CC during a brief postnatal critical period.

  3. Sp5 (show SP5 Proteins) and Sp8 are pivotal downstream effectors of Wnt3a (show WNT3A Proteins)/beta-catenin (show CTNNB1 Proteins) that are essential for the self-renewal and differentiation of neuromesodermal stem cells.

  4. Our data are compatible with Sp6 and Sp8 working together and in a dose-dependent manner as indispensable mediators of Wnt/betacatenin and Bmp signaling in the limb ectoderm

  5. Findings provide evidence that Sp8 and another transcription factor, COUP-TF1 (show NR2F1 Proteins), mutually repress each other's cortical neuroepithelial expression along the anterior-posterior and dorsoventral axes

  6. The zinc-finger protein Sp8 plays a supplementary role to Pax6 (show PAX6 Proteins) in establishing the pMN (show TBCE Proteins)/p3 domain boundary.

  7. Sp8 is required for normal craniofacial development.

  8. Almost all calretinin (show CALB2 Proteins) and secretagogin (show SCGN Proteins) positive juxtaglomerular neurons are relatively strongly Sp8 positive, whereas none of calbindin (show CALB1 Proteins) positive neurons is Sp8 positive.

  9. Our results suggest that Sp8 is required for the normal production of parvalbumin (show PVALB Proteins)-positive interneurons in the external plexiform layer of the olfactory bulb.

  10. observations indicate that Sp8 functions downstream of Wnt3 (show WNT3 Proteins), Fgf10 (show FGF10 Proteins), and Bmpr1a (show BMPR1A Proteins) in the signaling cascade that mediates apical ectodermal ridge formation

SP8 Protein Profile

Protein Summary

The protein encoded by this gene is an SP family transcription factor that in mouse has been shown to be essential for proper limb development. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Sp8 Transcription Factor Proteins (SP8)

  • Sp8 transcription factor (SP8)
  • Sp8 transcription factor (sp8)
  • trans-acting transcription factor 8 (Sp8)
  • btd protein
  • D930049B17Rik protein
  • mBtd protein

Protein level used designations for Sp8 Transcription Factor Proteins (SP8)

specificity protein 8 , transcription factor Sp8

GENE ID SPECIES
221833 Homo sapiens
776034 Gallus gallus
495143 Xenopus laevis
320145 Mus musculus
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