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SPOCK1 encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. Additionally we are shipping SPOCK1 Proteins (8) and SPOCK1 Kits (3) and many more products for this protein.
Showing 10 out of 32 products:
Human Polyclonal SPOCK1 Primary Antibody for IHC, WB - ABIN351002
Alliel, Perin, Jollès, Bonnet: Testican, a multidomain testicular proteoglycan resembling modulators of cell social behaviour. in European journal of biochemistry / FEBS 1993
Show all 4 references for 351002
Human Polyclonal SPOCK1 Primary Antibody for IHC (fro), IHC (p) - ABIN440835
Li, Chen, Chan, Liu, Kong, Qiu, Li, Yuan, Guan: SPOCK1 is regulated by CHD1L and blocks apoptosis and promotes HCC cell invasiveness and metastasis in mice. in Gastroenterology 2012
Human Polyclonal SPOCK1 Primary Antibody for IHC, IHC (p) - ABIN4358527
Damhofer, Medema, Veenstra, Badea, Popescu, Roelink, Bijlsma: Assessment of the stromal contribution to Sonic Hedgehog-dependent pancreatic adenocarcinoma. in Molecular oncology 2013
a novel TGF-beta (show TGFB1 Antibodies)-induced myoepithelial marker and enhanced invasion in breast cancer cells and correlated with poor prognosis
Our results suggested that microRNA-129-5p could directly specifically suppress SPOCK1, which might be one of the potential mechanisms in inhibiting cell processes including viability, proliferation, cell mitosis, migration, and invasiveness of gastric cancer cells.
SPOCK1 expression is significantly up-regulated in colorectal cancer tissues and associated with tumor size and stage. SPOCK1 stimulates the PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling pathway to inhibit cell apoptosis and promote tumor growth.
findings suggest that SPOCK1 is a critical mediator of tumor growth and metastasis in prostate cancer
Knockdown of SPOCK1 inhibits the proliferation.
This study suggests that SPOCK1 promotes proliferation, migration and invasion in glioma cells by activating PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) and Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathways, which provides a potential theoretical basis for clinical treatment of glioma.
SPOCK1 is highly expressed in ovarian cancer.SPOCK1 contributes to ovarian cancer development and metastasis.
These results suggest that up-regulation of SPOCK1 in ESCC induces EMT (show ITK Antibodies), thus promotes migration and invasion in ESCC cells.
Collectively, altered expression of PKP1 (show PKP1 Antibodies) and SPOCK1 appears to be a frequent and critical event in prostate cancer
SPOCK1 activates PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling.
results suggest a possibility that testican-1 plays a permissive role for regenerating axons in reactive astrocytes after injury
SPARC (show SPARC Antibodies) is counter-adhesive for murine lens epithelial cells. We also identify SPARC (show SPARC Antibodies) as a modulator of LN-1 (show PHYH Antibodies) secretion and deposition, an activity important in epithelial cell-ECM (show MMRN1 Antibodies) interactions in the ocular lens.
Testican-1 is not critical for mouse development [review]
This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition.
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
, sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
, testican 1