anti-Sperm Associated Antigen 6 (SPAG6) Antibodies

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Additionally we are shipping Sperm Associated Antigen 6 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SPAG6 291340  
SPAG6 9576 O75602
SPAG6 50525 Q9JLI7
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Top anti-Sperm Associated Antigen 6 Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-SPAG6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>HT1080 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB <b>WB Suggested Anti-SPAG6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate WB Suggested Anti-SPAG6 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB SPAG6 Antibody (C-term) (ABIN1881822) western blot analysis in MDA-MB453 cell line lysates (35 µg/lane). This demonstrates the SPAG6 antibody detected the SPAG6 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: SPAG6 Antibody [NBP2-20462] - Sample (30 ug of whole cell lysate) A: U87-MG 7. 5% SDS PAGE gel, diluted at 1:1000. Immunohistochemistry-Paraffin: SPAG6 Antibody [NBP2-20462] - Immunohistochemical analysis of paraffin-embedded H441 xenograft, using antibody at 1:500 dilution. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Mouse Un-conjugated WB SPAG6 monoclonal antibody (M01), clone 3E3 Western Blot analysis of SPAG6 expression in A-431. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB SPAG6 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
$473.93
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

SPAG6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Sperm Associated Antigen 6 Antibodies

  1. Cow (Bovine) Polyclonal SPAG6 Primary Antibody for WB - ABIN2785513 : Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: The LIFEdb database in 2006. in Nucleic acids research 2005 (PubMed)

More Antibodies against Sperm Associated Antigen 6 Interaction Partners

Human Sperm Associated Antigen 6 (SPAG6) interaction partners

  1. SPAG6 and L1TD1 are tumor-specifically methylated in NSCLCs and that DNA methylation is involved in the transcriptional regulation of these genes. Moreover, in vitro as well as in vivo experiments revealed tumor-cell growth suppressing properties of L1TD1 in NSCLC cells.

  2. Study demonstrates that SPAG6 may regulate apoptosis through the TRAIL signal pathway by inhibiting the expression of FADD and the interactions between FADD and the TRAIL death receptors.

  3. studies demonstrate a role for Spag6 in the pathogenesis of OM in mice, possibly through its role in the regulation of cilia/basal body polarity through the PCP (show PRCP Antibodies)-dependent mechanisms in the middle ear and Eustachian tubes.

  4. These findings demonstrate that SPAG6 might have a role in malignant myeloid hematologic cell proliferation and apoptosis by regulating caspase (show CASP3 Antibodies) proteins and p53 (show TP53 Antibodies), suggesting that SPAG6 may be a potential therapeutic target.

  5. SPAG6 is a S-SOX5 (show SOX5 Antibodies) target gene, indicating a key role for S-SOX5 (show SOX5 Antibodies) in the formation and function of motile cilia.

  6. Data describe the cloning of human and mouse Pf20 (show SPAG16 Antibodies) proteins that interact with Spag6 protein.

Mouse (Murine) Sperm Associated Antigen 6 (SPAG6) interaction partners

  1. SPAG6 binds to prestin (show SLC26A5 Antibodies) in vivo and contributes to fix prestin (show SLC26A5 Antibodies) biomolecules in lateral plasma membrane of outer hair cells.

  2. SPAG6 is a S-SOX5 (show SOX5 Antibodies) target gene, indicating a key role for S-SOX5 (show SOX5 Antibodies) in the formation and function of motile cilia.

  3. Spag6 is essential for sperm flagellar motility and that it is important for the maintenance of the structural integrity of mature sperm. The occurrence of hydrocephalus in the mutant mice also implicates Spag6 in the motility of ependymal cilia.

  4. Data describe the cloning of human and mouse Pf20 (show SPAG16 Antibodies) proteins that interact with Spag6 protein.

  5. Accelerated mortality from hydrocephalus and pneumonia in mice with combined deficiency of Spag6 and Spag16L reveals a functional interrelationship between the two central apparatus proteins.

  6. Spag6 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.

Sperm Associated Antigen 6 (SPAG6) Antigen Profile

Protein Summary

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SPAG6

  • sperm associated antigen 6-like (Spag6l) antibody
  • sperm associated antigen 6 (SPAG6) antibody
  • sperm associated antigen 6 (spag6) antibody
  • sperm associated antigen 6 (Spag6) antibody
  • sperm associated antigen 6 L homeolog (spag6.L) antibody
  • DKFZp459D035 antibody
  • PF16 antibody
  • Repro-SA-1 antibody
  • RGD1310892 antibody
  • SPAG6 antibody
  • zgc:91805 antibody

Protein level used designations for SPAG6

sperm associated antigen 6 , axoneme central apparatus protein , protein PF16 homolog , sperm flagellar protein , sperm-associated antigen 6 , axoneme protein

GENE ID SPECIES
291340 Rattus norvegicus
450348 Pan troglodytes
548730 Xenopus (Silurana) tropicalis
100134839 Meleagris gallopavo
100174630 Pongo abelii
9576 Homo sapiens
50525 Mus musculus
360747 Rattus norvegicus
431757 Danio rerio
734748 Xenopus laevis
420505 Gallus gallus
477978 Canis lupus familiaris
100286811 Sus scrofa
539424 Bos taurus
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