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S1PR3 encodes a member of the EDG family of receptors, which are G protein-coupled receptors. Additionally we are shipping S1PR3 Antibodies (145) and S1PR3 Proteins (6) and many more products for this protein.
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Sphingosine-1-phosphate receptor 3 (S1PR3) mediates multiple aspects of the inflammatory response during sepsis.
in breast cancer cells overexpression of S1P3 and its activation by S1P (show MBTPS1 ELISA Kits) has pro-inflammatory and pro-metastatic potential by inducing COX-2 (show COX2 ELISA Kits) expression and PGE2 signaling via EP2 and EP4 (show PTGER4 ELISA Kits).
S1PR1 (show S1PR1 ELISA Kits)/3 silencing alters proliferation, adhesion, viability and lateral motility in estrogen receptor (show ESR1 ELISA Kits)-negative MCF-7 and estrogen receptor (show ESR1 ELISA Kits)-positive MDA-MB-231 breast cancer cells.
High S1PR3 expression is associated with increased lung adenocarcinoma.
The S1P1,3 activation results in Akt (show AKT1 ELISA Kits) phosphorylation and subsequent activation of eNOS (show NOS3 ELISA Kits) via phosphorylation at serine(1177) and dephosphorylation at threonine(495).
HDL (show HSD11B1 ELISA Kits)-associated ApoM (show APOM ELISA Kits) is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 (show S1PR1 ELISA Kits) and S1P3 receptors on vascular endothelium.
The study shows that S1P receptor 3 (S1PR3) mRNA is overexpressed in EBV-positive NPC (show NPC1 ELISA Kits) patient-derived xenografts and a subset of primary NPC (show NPC1 ELISA Kits) tissues, and that knockdown of S1PR3 suppressed the activation of AKT (show AKT1 ELISA Kits) and the S1P (show MBTPS1 ELISA Kits)-induced migration of NPC (show NPC1 ELISA Kits) cells.
S1pr3 promotes leukocyte rolling by mobilization of endothelial P-selectin (show SELP ELISA Kits).
Stimulation with sphingosine-1-phosphate enhances cancer stem cells via S1PR3 and subsequent Notch1 (show NOTCH1 ELISA Kits) activation.
TRPC1 (show TRPC1 ELISA Kits) functions as a major regulator of S1P3 and VEGFR2 (show KDR ELISA Kits) expression.
The absence of S1P3 appears responsible for a lower availability of calcium during fatigue.
These results highlight an important role for S1PR3 in Hematopoietic stem and progenitor cell niche occupancy.
S1P3 deletion protects mouse soleus from age-related drop in muscle mass, force, and regenerative capacity.
The finding that S1P3 receptor- and Galpha13-mediated RhoA (show RHOA ELISA Kits) activation is responsible for protection against ischemia/reperfusion suggests that selective targeting of S1P3 receptors could provide therapeutic benefits in ischemic heart disease.
The role of the S1PR3/PDGFR-beta (show PDGFRB ELISA Kits)/Akt (show AKT1 ELISA Kits) pathway in sphingosine-1-phosphate -induced endothelial progenitor cells migration and angiogenesis
P2RY8 promotes clustering of activated B cells within follicles in a follicular dendritic cell (FDC)-dependent manner.
Smad3 (show SMAD3 ELISA Kits) deficiency leads to mandibular condyle degradation via the sphingosine 1-phosphate (S1P (show S1PR1 ELISA Kits))/S1P3 signaling axis
CTGF (show CTGF ELISA Kits) exerts profibrotic action in myoblasts via the up-regulation of sphingosine kinase-1 (show SPHK1 ELISA Kits)/S1P3 signaling axis in TGF-beta (show TGFB1 ELISA Kits) dependent manner.
This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.
sphingosine-1-phosphate receptor 3
, sphingosine 1-phosphate receptor 3-like
, G protein-coupled receptor, endothelial differentiation gene-3
, S1P receptor 3
, S1P receptor EDG3
, S1P receptor Edg-3
, endothelial differentiation G-protein coupled receptor 3
, endothelial differentiation, sphingolipid G-protein-coupled receptor, 3
, sphingosine 1-phosphate receptor 3
, sphingosine 1-phosphate receptor Edg-3
, S1p receptor 3
, endothelial differentiation sphingolipid G-protein-coupled receptor 3
, lysophospholipid receptor B3