You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) Antibodies

Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Additionally we are shipping SKA1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SKA1 220134 Q96BD8
SKA1 66468 Q9CPV1
SKA1 291441 B0BN28
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-SKA1 Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SKA1 in A549 cell lysate with SKA1 antibody at 0.5 µg/ml (A) and 1 μg/ml (B). 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of SKA1 in A549 cell lysate with SKA1 antibody at (A) 0.5 and (B) 1 µg/mL. 0.1 mg Log in to see 2 to 3 Days
$330.00
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 6 to 11 Days
$535.71
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

SKA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


, , , , , , , , , , ,
Mouse (Murine) ,


, , , , , , , , , , ,
Rat (Rattus) ,


, , , , , , , , , , ,

Top referenced anti-SKA1 Antibodies

  1. Human Polyclonal SKA1 Primary Antibody for EIA, WB - ABIN500728 : Cleveland, Mao, Sullivan: Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. in Cell 2003 (PubMed)
    Show all 4 references for ABIN500728

More Antibodies against SKA1 Interaction Partners

Human Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) interaction partners

  1. Thus, our findings identified a definite regulatory mechanism of the search and capture process for stable spindle attachment through cross-talk between spindle dynamics and KT composition mediated by DDA3 (show PSRC1 Antibodies) and Ska1.

  2. knockdown of SKA1 could potently suppress bladder cancer cell proliferation in vitro and lentivirus-mediated silencing of SKA1 might serve as a novel strategy for gene therapy of bladder cancer.

  3. Results show that high SKA1 expression is predictive of poor prognosis of papillary thyroid carcinoma (PTC (show F9 Antibodies)), implying it as a promising new target for PTC (show F9 Antibodies) therapies.

  4. SKA1 could be used for gastric cancer early diagnosis as a biomarker.

  5. the kinetochore-associated Ska complex interacts with tubulin (show TUBB Antibodies) monomers via the carboxy-terminal winged-helix domain of Ska1, providing the structural basis for the ability to bind both straight and curved microtubule structures.

  6. Ska1 over-expression promotes tumourigenesis

  7. Data suggest that SKA1 plays an important role in the proliferation of hepatocellular carcinoma cells

  8. the conserved kinetochore-localized Ska1 complex tracks with depolymerizing microtubule ends and associates with both the microtubule lattice and curved protofilaments

  9. The structure of the Ska core complex is a W-shaped dimer of coiled coils, formed by intertwined interactions between Ska1, Ska2 (show FAM33A Antibodies), and Ska3 (show SKA3 Antibodies).

  10. Data suggest that Aurora B phosphorylation antagonizes the interaction between the Ska1-3 complex and the KMN network, thereby controlling Ska recruitment to KTs and stabilization of KT-MT attachments.

Mouse (Murine) Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) interaction partners

  1. Ska1 over-expression promotes tumourigenesis

  2. The Ska1 subunit was only localized on spindle microtubules from the Pro-MI to MII stages in mouse oocyte meiosis and knockdown by Morpholino injection into mouse oocytes resulted in spindle movement defects and enlarged polar bodies.

SKA1 Antigen Profile

Protein Summary

Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules (By similarity).

Gene names and symbols associated with SKA1

  • spindle and kinetochore associated complex subunit 1 (SKA1) antibody
  • spindle and kinetochore associated complex subunit 1 (ska1) antibody
  • spindle and kinetochore associated complex subunit 1 (Ska1) antibody
  • 2810433K01Rik antibody
  • AV117428 antibody
  • C18H18orf24 antibody
  • C18orf24 antibody
  • RGD1310784 antibody

Protein level used designations for SKA1

spindle and kinetochore-associated protein 1 , spindle and KT (kinetochore) associated 1 , spindle and KT associated 1

GENE ID SPECIES
700712 Macaca mulatta
100144953 Xenopus (Silurana) tropicalis
220134 Homo sapiens
66468 Mus musculus
291441 Rattus norvegicus
491691 Canis lupus familiaris
507703 Bos taurus
Selected quality suppliers for anti-SKA1 (SKA1) Antibodies
Did you look for something else?