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Spindle and Kinetochore Associated Complex Subunit 3 Proteins (SKA3)

SKA3 encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. Additionally we are shipping SKA3 Antibodies (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SKA3 221150 Q8IX90
SKA3 219114 Q8C263
SKA3 361047  
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Top SKA3 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,116.67
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$3,402.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,166.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SKA3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

Rat (Rattus)

More Proteins for Spindle and Kinetochore Associated Complex Subunit 3 (SKA3) Interaction Partners

Human Spindle and Kinetochore Associated Complex Subunit 3 (SKA3) interaction partners

  1. over-expression of GNL3 (show E2IG3 Proteins) and SKA3 in the PC-3 (show PCSK1 Proteins) human prostate cancer cell line decreased in vitro cell migration and invasion

  2. The structure of the Ska core complex is a W-shaped dimer of coiled coils, formed by intertwined interactions between Ska1 (show SKA1 Proteins), Ska2 (show FAM33A Proteins), and Ska3.

  3. Data suggest that Aurora B phosphorylation antagonizes the interaction between the Ska1-3 complex and the KMN network, thereby controlling Ska recruitment to KTs and stabilization of KT-MT attachments.

  4. Ska3 functions to coordinate checkpoint signaling from the microtubule binding sites within a kinetochore by laterally linking the individual binding sites.

  5. C13Orf3 (now termed Ska3) localizes to the spindle and kinetochore throughout mitosis and its depletion markedly delays anaphase transition.

  6. These data identify C13orf3 (Ska3) as an important factor for metaphase to anaphase progression and highlight the potential of combined RNAi screening and protein localisation analyses.

  7. RAMA1 is a novel kinetochore protein involved in kinetochore-microtubule attachment.

Mouse (Murine) Spindle and Kinetochore Associated Complex Subunit 3 (SKA3) interaction partners

  1. The Ska3 subunit was only localized on spindle microtubules from the Pro-MI to MII stages in mouse oocyte meiosis and knockdown by Morpholino injection into mouse oocytes resulted in spindle movement defects and enlarged polar bodies.

SKA3 Protein Profile

Protein Summary

This gene encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. The encoded protein localizes to the outer kinetechore and may be required for normal chromosome segregation and cell division. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SKA3

  • spindle and kinetochore associated complex subunit 3 (SKA3)
  • zgc:113019 (zgc:113019)
  • spindle and kinetochore associated complex subunit 3 (ska3)
  • spindle and kinetochore associated complex subunit 3 (LOC100344062)
  • spindle and kinetochore associated complex subunit 3 (Ska3)
  • C12H13ORF3 protein
  • C13orf3 protein
  • F630043A04Rik protein
  • fc23d11 protein
  • RAMA1 protein
  • RGD1307201 protein
  • si:rp71-68n21.13 protein
  • wu:fc23d11 protein

Protein level used designations for SKA3

spindle and kinetochore associated complex subunit 3 , spindle and kinetochore-associated protein 3 , Spindle and kinetochore-associated protein RAMA1

GENE ID SPECIES
452468 Pan troglodytes
550590 Danio rerio
702839 Macaca mulatta
100055242 Equus caballus
100144945 Xenopus (Silurana) tropicalis
100344062 Oryctolagus cuniculus
100450023 Pongo abelii
100595589 Nomascus leucogenys
221150 Homo sapiens
219114 Mus musculus
361047 Rattus norvegicus
609400 Canis lupus familiaris
418948 Gallus gallus
509921 Bos taurus
100158292 Xenopus laevis
570479 Danio rerio
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