SplA/ryanodine Receptor Domain and SOCS Box Containing 2 Proteins (SPSB2)

SPSB2 encodes encodes a suppressor of cytokine signaling (SOCS) family member, and it belongs to the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. Additionally we are shipping SplA/ryanodine Receptor Domain and SOCS Box Containing 2 Antibodies (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SPSB2 84727 Q99619
SPSB2 14794 O88838
SPSB2 297592 Q5M877
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Top SplA/ryanodine Receptor Domain and SOCS Box Containing 2 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,684.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days
$382.86
Details

SPSB2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Top referenced SplA/ryanodine Receptor Domain and SOCS Box Containing 2 Proteins

  1. Human SPSB2 Protein expressed in Escherichia coli (E. coli) - ABIN1098440 : Wang, Li, Messing, Wu: The SPRY domain-containing SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathway. in The Journal of biological chemistry 2005 (PubMed)

More Proteins for SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) Interaction Partners

Human SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) interaction partners

Mouse (Murine) SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) interaction partners

  1. Collectively, Ssb1 (show SPSB1 Proteins) and Ssb2 control crucial aspects of Hematopoietic stem and progenitor cells function, including proliferation and survival in vivo by resolving replicative stress to maintain genomic stability.

  2. structural changes limit high-affinity interactions for SPSB2 to aspartate-containing sequences

  3. The SPRY domain-containing SOCS (show CISH Proteins) box protein SPSB2 targets iNOS (show NOS2 Proteins) for proteasomal degradation.

  4. Genetic deletion of SOCS (show CISH Proteins) Box Protein 2 results in a very mild thrombocytopenia.

  5. Determined the first SPRY-domain structure of SSB-2 that adopts a novel fold and contains conserved structural determinants for binding to prostate apoptosis response protein-4 (PAR-4 (show PAWR Proteins)).

  6. Backbone dynamics of SSB-2 by means of Modelfree analysis.

  7. The binding site on SSB-2 for the prostate apoptosis response-4 (Par-4 (show F2RL3 Proteins)) protein has been mapped in finer detail using mutational analyses.

SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) Protein Profile

Protein Summary

This gene encodes encodes a suppressor of cytokine signaling (SOCS) family member, and it belongs to the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. This gene is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SPSB2

  • splA/ryanodine receptor domain and SOCS box containing 2 (SPSB2)
  • splA/ryanodine receptor domain and SOCS box containing 2 (Spsb2)
  • AI461677 protein
  • C9 protein
  • Grcc9 protein
  • SSB2 protein

Protein level used designations for SPSB2

SPRY domain-containing SOCS box protein 2 , SPRY domain-containing SOCS box protein SSB-2 , gene-rich cluster protein C9 , SSB-2 , gene rich cluster, C9 , gene rich cluster, C9 gene protein

GENE ID SPECIES
84727 Homo sapiens
14794 Mus musculus
297592 Rattus norvegicus
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