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anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) Antibodies

SF3B1 encodes subunit 1 of the splicing factor 3b protein complex. Additionally we are shipping SF3B1 Proteins (3) and SF3B1 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SF3B1 81898  
SF3B1 84486  
SF3B1 23451 O75533
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Top anti-SF3B1 Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-SF3B1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB SF3B1 Antibody (N-term) (ABIN657676) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the SF3B1 antibody detected the SF3B1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, IP, WB 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Chicken Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-SF3B1 Antibody Titration: 1.25ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-SF3B1 Antibody Titration: 0.3125ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-SF3B1  Antibody Titration: 0.3125 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate  SF3B1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Log in to see 2 to 3 Days
$229.00
Details
Hamster Mouse Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of SAP155 expression in A431 (A), Ramos (B), SP2/0 (C), H9C2 (D) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Dog Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details

SF3B1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SF3B1 Antibodies

  1. Human Polyclonal SF3B1 Primary Antibody for IHC (p), WB - ABIN657676 : Corsini, Hothorn, Stier, Rybin, Scheffzek, Gibson, Sattler: Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60. in The Journal of biological chemistry 2008 (PubMed)
    Show all 3 references for ABIN657676

  2. Chicken Polyclonal SF3B1 Primary Antibody for WB - ABIN2779036 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)

  3. Hamster Monoclonal SF3B1 Primary Antibody for WB - ABIN1449178 : Horie, Isono, Koseki: Generation of a monoclonal antibody against the mouse Sf3b1 (SAP155) gene product for U2 snRNP component of spliceosome. in Hybridoma and hybridomics 2003 (PubMed)

  4. Chicken Polyclonal SF3B1 Primary Antibody for WB - ABIN2779035 : Avila, Bercovich, Westergaard, Levin, Vázquez: Mapping of the protein-binding interface between splicing factors SF3b155 and p14 of Trypanosoma cruzi. in Biochemical and biophysical research communications 2007 (PubMed)

  5. Chicken Polyclonal SF3B1 Primary Antibody for IHC, WB - ABIN2778700 : Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)

More Antibodies against SF3B1 Interaction Partners

Zebrafish Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) interaction partners

  1. Data indicate that splicing factor 3b (show SF3B14 Antibodies), subunit 1 (sf3b1) mutation causes aberrant splicing of sf3b1 resulting in functional and predicted non-functional transcripts and a 90% reduction in full-length Sf3b1 protein.

Mouse (Murine) Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) interaction partners

  1. myocardial hypoxia actuates fructose metabolism in human and mouse models of pathological cardiac hypertrophy through hypoxia-inducible factor 1alpha (HIF1alpha (show HIF1A Antibodies)) activation of SF3B1 and SF3B1-mediated splice switching of KHK (show KHK Antibodies)-A to KHK (show KHK Antibodies)-C

  2. Sf3b1 isrequired for the blastocyst formation.

  3. SF3B1 plays an important role in the regulation of hematopoietic stem cells, whereas SF3B1 haploinsufficiency itself is not associated with the myelodysplastic syndrome phenotype with ring sideroblasts.

  4. The level of Sf3b1 expression is critical for the proliferative capacity of hematopoietic stem cells. Depletion of Sf3b1 impairs proliferative capacity of hematopoietic stem cells but is not sufficient to induce myelodysplasia.

  5. SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes.

  6. the active spliceosome, containing SAP155 phosphorylated by DYRKIA, performs pre-mRNA splicing in spermatogonia during testicular development

  7. active spliceosome, containing phosphorylated SAP155, performs pre-mRNA splicing on chromatin concomitant with transcription during testicular development.

  8. Sf3b1 and Polycomb (show CBX2 Antibodies) group (PcG) proteins interaction is essential for true PcG-mediated repression of Hox (show MSH2 Antibodies) genes.

Human Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) interaction partners

  1. The finding of this study showed that an SF3B1 (show SF3B2 Antibodies) or EIF1AX (show EIF1AX Antibodies) mutation is present in a substantial subset of primary LMNs underscores that these tumors genetically resemble uveal melanoma and are different from cutaneous melanoma at the genetic level.

  2. SF3B1 (show SF3B2 Antibodies)-mutated myelodysplastic syndrome with ring sideroblasts harbors more severe iron overload and corresponding over-erythropoiesis.

  3. studies reveal new mechanistic insight into SF3B1 (show SF3B2 Antibodies) as a principal player in the spliceosome and as a target of inhibitor compounds

  4. SF3B1 (show SF3B2 Antibodies) - novel candidate genes validated in a large case-control sample of schizophrenia.

  5. In uveal melanoma, the SF3B1 (show SF3B2 Antibodies)(R625/K666) mutation results in deregulated splicing at a subset of junctions, mostly by the use of alternative 3'ss.

  6. Data show that tet methylcytosine dioxygenase 2 TET2 (show TET2 Antibodies), isocitrate dehydrogenases 1/2 IDH1 (show IDH1 Antibodies)/IDH2 (show IDH2 Antibodies), serine/arginine-rich splicing factor 2 SRSF2 (show SRSF2 Antibodies), splicing factor 3b subunit 1 SF3B1, and ras proteins (KRAS/NRAS) are not conserved in dog mast Cell tumors.

  7. SF3B1 (show SF3B2 Antibodies) mutations can propagate from hematopoietic stem cells to myeloid progeny causing myelodysplastic syndromes.

  8. Data suggest SF3B1 (show SF3B2 Antibodies) mutations as a biomarker that can aid in the diagnosis of patients with sideroblastic anemia (SA), allowing for the differentiation between clonal and non-clonal cases of SA.

  9. SF3B1 (show SF3B2 Antibodies) is associated with nucleosomes positioned over exons. SF3B1 (show SF3B2 Antibodies) binding of nucleosomes facilitates the splicing recognition of exons.

  10. Studying transcriptome sequencing data from chronic lymphocytic leukemia, breast cancer and uveal melanoma tumor samples, we show that hundreds of cryptic 3' splice sites (3'SSs) are used in cancers with SF3B1 (show SF3B2 Antibodies) mutations.

SF3B1 Antigen Profile

Protein Summary

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with SF3B1

  • splicing factor 3b, subunit 1, 155kDa (SF3B1) antibody
  • splicing factor 3b, subunit 1, 155kDa (sf3b1) antibody
  • splicing factor 3b, subunit 1 (sf3b1) antibody
  • splicing factor 3b, subunit 1 (Sf3b1) antibody
  • 155kDa antibody
  • 2810001M05Rik antibody
  • AA409119 antibody
  • Hsh155 antibody
  • MDS antibody
  • PRP10 antibody
  • PRPF10 antibody
  • sap155 antibody
  • SF3B1 antibody
  • SF3b155 antibody
  • TA-8 antibody
  • Targ4 antibody
  • wu:fb99f09 antibody

Protein level used designations for SF3B1

splicing factor 3b, subunit 1, 155kDa , splicing factor 3B subunit 1 , splicing factor 3B subunit 1-like , tst , SAP 155 , pre-mRNA-splicing factor SF3b 155 kDa subunit , spliceosome-associated protein 155 , splicing factor 3b, subunit 1, 155 kDa , transforming growth factor alpha regulated gene 4 , splicing factor 3b, subunit 1, 155kD , 146 kDa nuclear protein , SF3b155 , pre-mRNA processing 10 , pre-mRNA splicing factor SF3b, 155 kDa subunit

GENE ID SPECIES
459850 Pan troglodytes
510177 Bos taurus
697773 Macaca mulatta
100022236 Monodelphis domestica
100070506 Equus caballus
100413687 Callithrix jacchus
100477819 Ailuropoda melanoleuca
100547422 Meleagris gallopavo
100559157 Anolis carolinensis
100604147 Nomascus leucogenys
446117 Danio rerio
81898 Mus musculus
84486 Rattus norvegicus
399336 Xenopus laevis
424056 Gallus gallus
23451 Homo sapiens
488456 Canis lupus familiaris
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