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Splicing Factor 3b, Subunit 2, 145kDa Proteins (SF3B2)

SF3B2 encodes subunit 2 of the splicing factor 3b protein complex. Additionally we are shipping Splicing Factor 3b, Subunit 2, 145kDa Antibodies (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse SF3B2 SF3B2 319322  
SF3B2 10992 Q13435
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Top Splicing Factor 3b, Subunit 2, 145kDa Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SF3B2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Splicing Factor 3b, Subunit 2, 145kDa (SF3B2) Interaction Partners

Human Splicing Factor 3b, Subunit 2, 145kDa (SF3B2) interaction partners

  1. High SF3B2 expression is associated with hepatocellular carcinoma.

  2. Although amino acid substitutions of residues surrounding Arg-508 had no great effect on PRMT9 (show FBXO11 Proteins) recognition of SF3B2, moving the arginine residue within this sequence abolished methylation.

  3. Inhibiting the induction of two proteins involved in two of the most significantly upregulated cellular processes, ribosome biogenesis (eIF6 (show EIF6 Proteins)) and hnRNA splicing (SF3B2/SF3B4 (show SF3B4 Proteins)), showed that human T cells can enter the cell cycle without growing in size.

  4. Data show that Vpr induces checkpoint activation and G(2) arrest by binding to the CUS1 domain of SAP145 and interfering with the functions of the SAP145 and SAP49 (show SF3B4 Proteins) proteins, two subunits of the multimeric splicing factor 3b (show SF3B14 Proteins) (SF3b).

Splicing Factor 3b, Subunit 2, 145kDa (SF3B2) Protein Profile

Protein Summary

This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.

Gene names and symbols associated with SF3B2

  • splicing factor 3b, subunit 2 (Sf3b2)
  • splicing factor 3b, subunit 2, 145kDa (SF3B2)
  • splicing factor 3b, subunit 2, 145kDa (sf3b2)
  • 145kDa protein
  • 2610311M13Rik protein
  • 2810441F20Rik protein
  • B230398H18Rik protein
  • Cus1 protein
  • sap145 protein
  • SF3b1 protein
  • SF3B2 protein
  • SF3B145 protein
  • sf3b150 protein

Protein level used designations for SF3B2

splicing factor 3B subunit 2 , splicing factor 3b, subunit 2, 145kDa , splicing factor 3B subunit 2-like , SAP 145 , pre-mRNA splicing factor SF3b 145 kDa subunit , pre-mRNA-splicing factor SF3b 145 kDa subunit , spliceosome associated protein 145 , spliceosome-associated protein 145

GENE ID SPECIES
319322 Mus musculus
451343 Pan troglodytes
476015 Canis lupus familiaris
531931 Bos taurus
714747 Macaca mulatta
734465 Xenopus laevis
100052173 Equus caballus
100170589 Xenopus (Silurana) tropicalis
100445486 Pongo abelii
100483831 Ailuropoda melanoleuca
100522004 Sus scrofa
10992 Homo sapiens
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