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SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. Additionally we are shipping Splicing Regulatory Glutamine/lysine-Rich Protein 1 Antibodies (17) and Splicing Regulatory Glutamine/lysine-Rich Protein 1 Proteins (4) and many more products for this protein.
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From among the 500 splicing events exhibiting altered splicing under these conditions, the splicing of c-Jun (show JUN ELISA Kits) and IkappaBbeta (show NFKBIB ELISA Kits) were validated as being regulated by SRrp86 resulting in altered regulation of their downstream targets.
SRrp86 can activate SRp20 (show SRSF3 ELISA Kits) and repress SC35 (show SRSF2 ELISA Kits) in a dose-dependent manner both in vitro and in vivo
the unique glutamic acid-lysine domain of SRrp86 plays a modulatory role controlling serine-arginine domain function
p18SRP (show SFRS12IP1 ELISA Kits) is a lysine-rich zinc finger domain-containing protein (show LMO7 ELISA Kits) that interacts with the serine-arginine-rich splicing regulatory protein SRrp86; it is downregulated in brain of Alzheimer disease patients.
This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
serine-arginine-rich splicing regulatory protein 508
, serine/arginine-rich-splicing regulatory protein 86
, splicing factor, arginine/serine-rich 12
, splicing regulatory protein 508
, serine/arginine-rich splicing factor 12
, SR-related protein of 86 kDa
, serine-arginine-rich splicing regulatory protein 86
, serine-arginine-rich-splicing regulatory protein 86