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SPRED3 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004. Additionally we are shipping Sprouty-Related, EVH1 Domain Containing 3 Proteins (3) and many more products for this protein.
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Human Polyclonal SPRED3 Primary Antibody for EIA, IHC (p) - ABIN954940
King, Corcoran, DAbaco, Straffon, Smith, Poon, Buchert, I, Hall, Lock, Hovens: Eve-3: a liver enriched suppressor of Ras/MAPK signaling. in Journal of hepatology 2006
Show all 4 references for ABIN954940
Human Polyclonal SPRED3 Primary Antibody for EIA, IHC (p) - ABIN500802
Kato, Nonami, Taketomi, Wakioka, Kuroiwa, Matsuda, Yoshimura: Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation. in Biochemical and biophysical research communications 2003
The finding of Spred-3 revealed the presence of a novel family of regulators for the Ras/MAP kinase (show MAPK1 Antibodies) pathway, each member of which may have different specificities for extracellular signals. [Spred-3]
Eve-3 may act as an inhibitor of proliferation pathways in the mature liver and be involved in modulating the unique regenerative capacity of this organ
This gene encodes a protein with a C-terminal Sprouty-like cysteine-rich domain (SRY) and an N-terminal Ena/Vasodilator-stimulated phosphoprotein (VASP) homology-1 (EVH-1) domain. The encoded protein is a member of a family of proteins that negatively regulates mitogen-activated protein (MAP) kinase signaling, particularly during organogenesis. Alternative splicing results in multiple transcript variants.
sprouty-related, EVH1 domain containing 3
, sprouty-related, EVH1 domain-containing protein 3
, Sprouty-related EVH1 domain-containing protein