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SPRED3 antibody (Center)

SPRED3 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500802
  • Target See all SPRED3 Antibodies
    SPRED3 (Sprouty-Related, EVH1 Domain Containing 3 (SPRED3))
    Binding Specificity
    • 8
    • 8
    • 7
    • 1
    Center
    Reactivity
    • 16
    • 9
    Human
    Host
    • 16
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    This SPRED3 antibody is un-conjugated
    Application
    • 16
    • 13
    • 13
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects Spred3 at center. It is predicted to have no cross-reactivity to Spred1 or Spred2.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Peptide affinity chromatography
    Immunogen
    Spred3 antibody was raised against a 16 amino acid peptide near the center of the human Spred3.
    Isotype
    IgG
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    Discover our top product SPRED3 Primary Antibody
  • Application Notes
    ELISA. Western blot: 2 - 4 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    SPRED3 (Sprouty-Related, EVH1 Domain Containing 3 (SPRED3))
    Alternative Name
    Spred3 (SPRED3 Products)
    Synonyms
    si:ch211-255l12.2 antibody, RGD1311713 antibody, Eve-3 antibody, spred-3 antibody, AW047143 antibody, D130060H24Rik antibody, Spred-3 antibody, sprouty related EVH1 domain containing 3 antibody, sprouty-related, EVH1 domain containing 3 antibody, SPRED3 antibody, spred3 antibody, Spred3 antibody
    Background
    Spred3 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1 and Spred2, Spred3 contains and EVH1 domain in its amino terminus and a Sprouty-related cysteine-rich (SPR) domain in its C-terminus, but does not possess a functional c-kit binding domain (KBD). The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Although Spred3 was initially reported to be expressed in brain, at least one report also indicates that Spred3 can be found in liver. At least two isoforms of Spred3 are known to exist.Synonyms: EVE-3, Sprouty-related EVH1 domain-containing protein 3
    Gene ID
    399473
    NCBI Accession
    NP_001035987
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