Src-Like-Adaptor (SLA) ELISA Kits

Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis (By similarity). Additionally we are shipping Src-Like-Adaptor Antibodies (21) and Src-Like-Adaptor Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SLA 211006 Q6P6M7
SLA 338477 P59622
SLA 6503 Q13239
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More ELISA Kits for Src-Like-Adaptor Interaction Partners

Mouse (Murine) Src-Like-Adaptor (SLA) interaction partners

  1. SLAP and SLAP2 are critical inhibitors of platelet (hem)ITAM signaling in the setting of arterial thrombosis and ischemic stroke

  2. SLAP is a critical regulator of B-cell development and function and its deficiency leads to decreased autoreactive B cells that are otherwise maintained by inefficient receptor editing or failed negative selection.

  3. Src-like adaptor protein (SLAP) functions as a negative regulator of the granulocyte-macrophage colony-stimulating factor receptor (show CSF2RA ELISA Kits) (GM-CSFR (show CSF2RA ELISA Kits)) generation of monocyte-derived dendritic cells of bone marrow origin.

  4. SLAP deficiency dramatically reduces both the incidence and severity of arthritis and prevents development of chronic arthritis in the double SKG (mutant ZAP70 (show ZAP70 ELISA Kits)) Src-like adapter protein (SLAP) knockout mouse model.

  5. SLAP negatively regulates differentiation of osteoclasts and proliferation of their precursors.

  6. SLAP functions in a pathway that requires the phosphorylated TCRzeta (show CD247 ELISA Kits) chain and the Src (show SRC ELISA Kits) family kinase Lck (show LCK ELISA Kits), but not ZAP-70 (show ZAP70 ELISA Kits) (zeta-associated protein of 70 kD).

  7. SLAP has a conserved function in B and T cells by adapting c-Cbl (show CBL ELISA Kits) to the antigen-receptor complex and targeting it for degradation

  8. SECp43 (show TRNAU1AP ELISA Kits) and SLA (show HEPH ELISA Kits) have roles in selenoprotein synthesis [soluble liver antigen]

Zebrafish Src-Like-Adaptor (SLA) interaction partners

  1. overexpression of SLalpha and SLbeta enhanced transcription of IGFs, insulin (show INS ELISA Kits), leptin (show LEP ELISA Kits), sterol regulatory element binding protein 1 (show SREBF1 ELISA Kits), and fatty acid synthase (show FASN ELISA Kits), as well as expression of vitellogenin (show VTG ELISA Kits) and proopiomelanocortin (show POMC ELISA Kits) in transgenic larvae

Human Src-Like-Adaptor (SLA) interaction partners

  1. results suggest that cytoplasm-specific transduction of the SH3 and SH2 domains of SLAP has a therapeutic potential of being an immunosuppressive reagent for the treatment of various autoimmune diseases

  2. Taken together the data demonstrate that SLAP negatively regulates wild-type c-Kit (show KIT ELISA Kits) signaling, but not its oncogenic counterpart, indicating a possible mechanism by which the oncogenic c-Kit (show KIT ELISA Kits) bypasses the normal cellular negative feedback control

  3. upon ligand stimulation SLAP stably associates with Flt3 (show FLT3 ELISA Kits) through multiple phosphotyrosine residues in Flt3 (show FLT3 ELISA Kits). SLAP mRNA is differentially expressed in different cancers and its expression significantly increased in patients carrying the Flt3 (show FLT3 ELISA Kits)-ITD mutation

  4. These data provide evidence for src-like adaptor protein-dependent regulation of CD3 zeta-chain in the fine control of TCR signaling.

  5. Although SLA is a prominent glucocorticoids response gene, it does not seem to contribute to the anti-leukemic effects of glucocorticoids.

  6. The SLA molecule and its functionally relevant residues have been highly conserved throughout the evolution.

Src-Like-Adaptor (SLA) Antigen Profile

Antigen Summary

Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis (By similarity).

Gene names and symbols associated with Src-Like-Adaptor (SLA) ELISA Kits

  • Src-like-adaptor (SLA) antibody
  • Src-like-adaptor (LOC100223615) antibody
  • Src-like-adaptor (LOC100339379) antibody
  • Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase (Sepsecs) antibody
  • somatolactin alpha (smtla) antibody
  • src-like adaptor (Sla) antibody
  • 9130208G10 antibody
  • AA986712 antibody
  • D5Ertd135e antibody
  • SecS antibody
  • sla antibody
  • SLA1 antibody
  • SLAP antibody
  • Slap-1 antibody
  • Slap1 antibody
  • src-like-adapter antibody

Protein level used designations for Src-Like-Adaptor (SLA) ELISA Kits

Src-like-adaptor , O-phosphoseryl-tRNA(Sec) selenium transferase , UGA suppressor tRNA-associated protein , sec synthase , selenocysteine synthase , selenocysteinyl-tRNA(Sec) synthase , sep-tRNA:Sec-tRNA synthase , SLAP-1 , src-like-adapter , src-like-adapter protein 1 , mSLAP , src-like adapter protein , src-like adaptor protein , hSLAP , src-like adaptor

697377 Macaca mulatta
100223615 Taeniopygia guttata
100339379 Oryctolagus cuniculus
211006 Mus musculus
572522 Danio rerio
338477 Rattus norvegicus
20491 Mus musculus
6503 Homo sapiens
378908 Gallus gallus
608259 Canis lupus familiaris
513589 Bos taurus
464409 Pan troglodytes
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