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StAR-Related Lipid Transfer (START) Domain Containing 5 Proteins (STARD5)

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1\; MIM 184756) and by liver X receptors (e.g., LXRA\; MIM 602423). Additionally we are shipping STARD5 Antibodies (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
STARD5 80765 Q9NSY2
STARD5 170460 Q9EPQ7
Rat STARD5 STARD5 502348  
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Top STARD5 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,526.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

STARD5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for StAR-Related Lipid Transfer (START) Domain Containing 5 (STARD5) Interaction Partners

Human StAR-Related Lipid Transfer (START) Domain Containing 5 (STARD5) interaction partners

  1. Studies show the 3 steroidogenic acute regulatory-related lipid transfer (START) domain proteins StarD4 (show STARD4 Proteins), StarD5 and StarD6 (show STARD6 Proteins) have a similar lipid binding pocket specific for sterols (cholesterol in particular), but differing regulation and localization.

  2. StarD4 (show STARD4 Proteins) is regulated by sterols via SREBP-2 (show SREBF2 Proteins), and StarD5 is activated by ER stress cholesterol metabolism; they serve different functions

  3. demonstrated StarD5 protein in liver cytosolic fractions only, suggesting StarD5 as a directional cytosolic sterol carrier

  4. The presence of StarD5 different human liver cells that are related to inflammatory processes provides new clues to its role of in free sterol transport in the cells and in lipid-mediated atherogenesis.

  5. Data support STARD5 functioning in kidney, specifically within proximal tubule cells, and suggest a role in ER-associated cholesterol transport.

Mouse (Murine) StAR-Related Lipid Transfer (START) Domain Containing 5 (STARD5) interaction partners

  1. StarD4 (show STARD4 Proteins) is regulated by sterols via SREBP-2 (show SREBF2 Proteins), and StarD5 is activated by ER stress cholesterol metabolism; they serve different functions

  2. Data support STARD5 functioning in kidney, specifically within proximal tubule cells, and suggest a role in ER-associated cholesterol transport.

STARD5 Protein Profile

Protein Summary

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1\; MIM 184756) and by liver X receptors (e.g., LXRA\; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR\; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD5 (Soccio et al., 2002

Gene names and symbols associated with STARD5

  • StAR-related lipid transfer (START) domain containing 5 (STARD5)
  • StAR-related lipid transfer (START) domain containing 5 (stard5)
  • StAR-related lipid transfer (START) domain containing 5 (Stard5)
  • 2310058G22Rik protein
  • AI607880 protein
  • D7Ertd152e protein
  • DKFZp469N2125 protein
  • MGC131265 protein
  • RGD1561783 protein
  • STARD5 protein

Protein level used designations for STARD5

StAR-related lipid transfer (START) domain containing 5 , START domain containing 5 , StAR-related lipid transfer protein 5 , START domain-containing protein 5 , stAR-related lipid transfer protein 5 , 18B7-T7(GS) , StAR-related protein 1-4E , StAR-related protein p3-15E/p3-16E

GENE ID SPECIES
467741 Pan troglodytes
770108 Gallus gallus
713308 Macaca mulatta
734829 Xenopus laevis
100173030 Pongo abelii
80765 Homo sapiens
100685077 Canis lupus familiaris
170460 Mus musculus
502348 Rattus norvegicus
512369 Bos taurus
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