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Although the function of STARD7 is not known, its existence is supported by mRNA and EST data. Additionally we are shipping STARD7 Antibodies (35) and many more products for this protein.
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Human STARD7 Protein expressed in Escherichia coli (E. coli) - ABIN1047680
Durand, Angeletti, Genti-Raimondi: GTT1/StarD7, a novel phosphatidylcholine transfer protein-like highly expressed in gestational trophoblastic tumour: cloning and characterization. in Placenta 2004
Show all 2 references for ABIN1047680
StarD7 modulates ABCG2 multidrug transporter level, cell migration, proliferation, and biochemical and morphological differentiation marker expression in a human trophoblast cell model.
StarD7 behaves as a fusogenic protein in model and cell membrane bilayers.
The SF-1 and beta-catenin pathway convergence on StarD7 expression may have important implications in the phospholipid uptake and transport, contributing to the normal trophoblast development.
These results suggest that StarD7 facilitates the delivery of phosphatidylcholine (show SGMS2 Proteins) to mitochondria in non-vesicular system.
Beta-catenin (show CTNNB1 Proteins) and TCF4 (show TCF4 Proteins) activate the human StarD7 gene interacting with its promoter region through Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signalling.
these data suggest that Stard7 is an important component of a novel protective pathway in tissues exposed to the extracellular environment.
Although the function of this gene is not known, its existence is supported by mRNA and EST data. The predicted gene product contains a region similar to the STAR-related lipid transfer (START) domain, which is often present in proteins involved in the cell signaling mediated by lipid binding. Alternatively spliced transcript variants have been described, although some transcripts occur only in cancer cell lines.
START domain containing 7
, stAR-related lipid transfer protein 7, mitochondrial
, START domain-containing protein 7
, gestational trophoblastic tumor protein 1