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Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2) ELISA Kits

SRD5A2 encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. Additionally we are shipping Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Antibodies (67) and Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SRD5A2 94224 Q99N99
SRD5A2 6716 P31213
SRD5A2 64677 P31214
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Top Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) ELISA Kits at antibodies-online.com

Showing 4 out of 15 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 0.28 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$880.00
Details
Human 0.126 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
$810.53
Details
Mouse 0.156-10 ng/mL   96 Tests Log in to see 11 to 13 Days
$1,029.60
Details
Pig
  96 Tests Log in to see 11 to 13 Days
$1,029.60
Details

Top referenced Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) ELISA Kits

  1. Rat (Rattus) SRD5A2 ELISA Kit for Sandwich ELISA - ABIN1117890 : Jang, Bae, Yuk, Han, Ha, Hwang, Yoon, Kim, Han: Seoritae extract reduces prostate weight and suppresses prostate cell proliferation in a rat model of benign prostate hyperplasia. in Evidence-based complementary and alternative medicine : eCAM 2014 (PubMed)

More ELISA Kits for Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Interaction Partners

Mouse (Murine) Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2) interaction partners

  1. observed an abnormally high expression levels of type 2 5alpha-reductase and 20alpha-HSD in the male and female adrenals, respectively, thus indirectly suggesting new roles for these sex-specific enzymes

  2. The induction of Srd5a2 through SREBP-2 (show SREBF2 ELISA Kits) provides a mechanistic explanation for why even though statin therapy is effective in reducing cholesterol levels in treating hypercholesterolemia it does not compromise androgen production in clinical studies.

Human Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2) interaction partners

  1. Results suggest that SRD5A2 controls cell migration by indirectly regulating ERK/MAPK (show MAPK1 ELISA Kits) pathway in prostate cancer cells.

  2. Metabolic syndrome develops more frequently in testicular cancer survivors homozygous or heterozygous variant for SNP rs523349 in SRD5A2.

  3. the V89L and TA repeat polymorphisms of SRD5A2 gene were found to have no significant associations with breast cancer

  4. the genotypic distribution of 22 single nucleotide polymorphisms in SRD5A1 (show SRD5A1 ELISA Kits) and SRD5A2 in a set of Spanish prostate cancer patients, were evaluated.

  5. In prostate cancer, increased DNA methylation (show HELLS ELISA Kits) of SRD5A2 and CYP11A1 (show CYP11A1 ELISA Kits) related to androgen biosynthesis functions may play a role in biochemical recurrence after patients' prostatectomy

  6. SRD5A2 gene polymorphisms are associated with the risk of benign prostatic hyperplasia but not prostate cancer.

  7. methylation of SRD5A2 is regulated by DNA methyltransferase 1 (show DNMT1 ELISA Kits), and inflammatory mediators such as tumor necrosis factor alpha (show TNF ELISA Kits), NF-kappaB (show NFKB1 ELISA Kits), and IL-6 (show IL6 ELISA Kits) regulate DNA methyltransferase 1 (show DNMT1 ELISA Kits) expression and thereby affect SRD5A2 promoter methylation and gene expression.

  8. High 5alpha-reductase activity due to the polymorphism in SRD5A2 may contribute to resistance to androgen deprivation therapy.

  9. Manipulation of SRD5A2 activity can regulate lipogenesis in human hepatocytes in vitro.

  10. Expression of the genes HSD3B1 (show HSD3B1 ELISA Kits), HSD17B3 (show HSD17B3 ELISA Kits), and SRD5A2 was significantly increased in BPH (show GLI3 ELISA Kits) tissues compared to normal adjacent prostate tissues.

Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2) Antigen Profile

Antigen Summary

This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).

Gene names and symbols associated with SRD5A2

  • steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (SRD5A2) antibody
  • steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (srd5a2) antibody
  • steroid-5-alpha-reductase alpha polypeptide 2 (srd5a2) antibody
  • steroid 5 alpha-reductase 2 (Srd5a2) antibody
  • steroid 5-alpha-reductase 2 (ST5AR2) antibody
  • steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (Srd5a2) antibody
  • 5ART2 antibody
  • S5AR 2 antibody
  • Srd5a2 antibody
  • SRD5alpha2 antibody

Protein level used designations for SRD5A2

3-oxo-5-alpha-steroid 4-dehydrogenase 2 , steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) , steroid-5-alpha-reductase alpha polypeptide 2 , 5 alpha-SR2 , SR type 2 , steroid 5 alpha reductase type2 , steroid 5-alpha-reductase 2 , S5AR 2 , type II 5-alpha reductase , prostatic steroid 5-alpha-reductase type II

GENE ID SPECIES
527024 Bos taurus
772291 Gallus gallus
549867 Xenopus (Silurana) tropicalis
705676 Macaca mulatta
100125532 Oryzias latipes
94224 Mus musculus
397048 Sus scrofa
6716 Homo sapiens
64677 Rattus norvegicus
403715 Canis lupus familiaris
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