You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Sterol Carrier Protein 2 (SCP2) Antibodies

SCP2 encodes two proteins (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. Additionally we are shipping SCP2 Kits (13) and SCP2 Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCP2 52468 Q8BX07
SCP2 6342 P22307
SCP2 25541 P11915
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-SCP2 Antibodies at antibodies-online.com

Showing 10 out of 122 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SCP2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate Host: Rabbit  Target Name: SCP2  Sample Tissue: Human Fetal Lung  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of SCP2 Antibody (Center) (ABIN652579) in A2058 cell line lysates (35 µg/lane). SCP2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SCP2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB SCP2 Antibody (N-term)  western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the SCP2 antibody detected the SCP2 protein (arrow). SCP2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SCP2 Antibody (N-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SCP2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of SCP2 Antibody (Center) in A2058 cell line lysates (35ug/lane). SCP2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human liver tissue stained with SCP2 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of SCP2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of SCP2 Antibody (N-term) Cat.-No AP53816PU-N in T47D cell line lysates (35ug/lane). This demonstrates the SCP2 antibody detected the SCP2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Guinea Pig Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, IHC (p) 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Goat Un-conjugated IHC (p), ELISA Anti-SCP2 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104148 concentration 27454 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details

SCP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , , , ,
,

, , , , , , , , , , ,
Human , , , ,
, ,
,
, , , , , , , , , , , , , ,
Rat (Rattus) , , , ,
,

, , , , , , , , , , ,

Top referenced anti-SCP2 Antibodies

  1. Human Polyclonal SCP2 Primary Antibody for EIA, IHC (p) - ABIN954693 : Dansen, Kops, Denis, Jelluma, Wanders, Bos, Burgering, Wirtz: Regulation of sterol carrier protein gene expression by the forkhead transcription factor FOXO3a. in Journal of lipid research 2004 (PubMed)
    Show all 5 references for ABIN954693

  2. Human Polyclonal SCP2 Primary Antibody for IHC (p), WB - ABIN656448 : Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: An approach based on a genome-wide association study reveals candidate loci for narcolepsy. in Human genetics 2010 (PubMed)
    Show all 2 references for ABIN656448

  3. Human Polyclonal SCP2 Primary Antibody for EIA, WB - ABIN453819 : Baker, Billheimer, Strauss: Similarity between the amino-terminal portion of mammalian 58-kD sterol carrier protein (SCPx) and Escherichia coli acetyl-CoA acyltransferase: evidence for a gene fusion in SCPx. in DNA and cell biology 1992 (PubMed)
    Show all 2 references for ABIN453819

  4. Human Polyclonal SCP2 Primary Antibody for FACS, IHC (p) - ABIN652579 : Vila, Levchenko, Korytowski, Girotti: Sterol carrier protein-2-facilitated intermembrane transfer of cholesterol- and phospholipid-derived hydroperoxides. in Biochemistry 2004 (PubMed)

  5. Human Polyclonal SCP2 Primary Antibody for WB - ABIN2786761 : Stanley, Versluis, Schultz, Heck, Wilmanns: Investigation of the ligand spectrum of human sterol carrier protein 2 using a direct mass spectrometry assay. in Archives of biochemistry and biophysics 2007 (PubMed)

More Antibodies against SCP2 Interaction Partners

Mouse (Murine) Sterol Carrier Protein 2 (SCP2) interaction partners

  1. Sterol Carrier Protein-2, a Nonspecific Lipid-Transfer Protein, in Intracellular Cholesterol Trafficking in Testicular Leydig Cells

  2. L-FABP (show FABP1 Antibodies) was more important in hepatic retention of bile acids, while SCP-2/SCP-x more broadly affected biliary bile acid and phospholipid levels.

  3. Loss of L-FABP (show FABP1 Antibodies) and SCP-2 (show CRISP3 Antibodies), or both induces hepatic lipid accumulation in female mice and mimics non-alcoholic fatty liver disease.

  4. CTDSP2 (show CTDSP2 Antibodies) induces p21(Cip1/Waf1 (show CDKN1A Antibodies)) through increasing the activity of Ras.

  5. SCP-2/SCP-x may function more in formation and biliary secretion of bile acid, with less impact on hepatic uptake or biliary secretion of HDL (show HSD11B1 Antibodies)-cholesterol

  6. liver fatty acid-binding protein, the single most prevalent hepatic cytosolic protein that binds cholesterol, was upregulated twofold in SCP-2 (show CRISP3 Antibodies) null hepatocytes

  7. SCP-2 expression plays a significant role in HDL-mediated cholesterol efflux by regulating the size of rapid vs. slow cholesterol efflux pools and/or eliciting concomitant upregulation of L-FABP in cultured primary hepatocytes.

  8. Effect of Scp2 (show CRISP3 Antibodies) expression on the rate of sterol transfer from lysosomal membranes, and lysosomal membrane lipid distribution.

  9. Data show that expression of sterol carrier protein-2 (SCP-2) increased fatty acid uptake and targeted fatty acid to unique lipid pools, suggesting that SCP-2 (show CRISP3 Antibodies) may effectively serve as universal fatty acid binding and trafficking protein.

  10. Results suggest a key regulatory role for sterol carrier protein-2 in hepatic lipid metabolism.

Human Sterol Carrier Protein 2 (SCP2) interaction partners

  1. We conclude that SCP-2 (show CTDSP2 Antibodies) is a low affinity binding protein for arachidonylethanolamine that can facilitate its cellular uptake but does not contribute significantly to intracellular sequestration of AEA.

  2. The Peroxisomal targeting signal 1 in Scp2 (show CTDSP2 Antibodies) is autonomous and is essential for binding to pex5 (show PEX5 Antibodies).

  3. cellular SCP-2 (show CTDSP2 Antibodies) not only binds and translocates cholesterol but also cholesterol hydroperoxides, thus expanding their redox toxicity and signaling ranges under oxidative stress conditions

  4. Statistical analysis indicated that six genes, NFATC2, SCP2, CACNA1C, TCRA, POLE, and FAM3D, were associated with narcolepsy.

  5. data for the first time showed that while the N-terminal membrane binding domain of SCP(2 (show CTDSP2 Antibodies)) was itself inactive in mediating intermembrane sterol transfer, it nevertheless potentiated the ability of SCP(2 (show CTDSP2 Antibodies)) to enhance sterol transfer

  6. SCP2 (show CTDSP2 Antibodies) in the cellular defense against oxidative damage and found that a fluorescent fatty acid analog bound to SCP2 (show CTDSP2 Antibodies) is protected against H2O2/Cu2+-induced oxidative damage

  7. Overexpression of human SCP-2 (show CTDSP2 Antibodies) in murine fibroblasts significantly alters the sterol dynamics of caveolae/lipid rafts, but not nonlipid raft domains, to facilitate retention of cholesterol within the cell.

  8. By trafficking cholesterol hydroperoxides and phospholipid hydroperoxides in addition to parent lipids, SCP2 (show CTDSP2 Antibodies) may exacerbate cell injury under oxidative stress conditions

  9. Long chain fatty acyl-coenzyme A (show SOAT2 Antibodies) (CoA)s are confirmed to be high affinity ligands for SCP2 (show CTDSP2 Antibodies), while long chain fatty acyl-carnitines are demonstrated for the first time not to interact with SCP2 (show CTDSP2 Antibodies).

  10. the importance of the N-terminal presequence in regulating SCP-2 (show CTDSP2 Antibodies) structure, cholesterol localization within the ligand binding site, membrane association, and, potentially, intracellular targeting

Cow (Bovine) Sterol Carrier Protein 2 (SCP2) interaction partners

  1. By trafficking cholesterol hydroperoxides and phospholipid hydroperoxides in addition to parent lipids, SCP2 may exacerbate cell injury under oxidative stress conditions. [sterol carrier protein 2, SCP2, nonspecific lipid transfer protein]

SCP2 Antigen Profile

Protein Summary

This gene encodes two proteins (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Gene names and symbols associated with SCP2

  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 (Ctdsp2) antibody
  • phospholipid transfer protein homolog1 (plt1) antibody
  • sterol carrier protein 2 (SCP2) antibody
  • sterol carrier protein 2 (Scp2) antibody
  • sterol carrier protein 2, liver (Scp2) antibody
  • AA409774 antibody
  • AA409893 antibody
  • AI586070 antibody
  • C76618 antibody
  • C79031 antibody
  • D10Ertd73e antibody
  • NLTP antibody
  • ns-LTP antibody
  • NSL-TP antibody
  • NSLIPTR antibody
  • OS-4 antibody
  • OS4 antibody
  • PLTP antibody
  • SCP-2 antibody
  • SCP-CHI antibody
  • SCP-X antibody
  • SCP2 antibody
  • SCPx antibody

Protein level used designations for SCP2

carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 , nuclear LIM interactor-interacting factor 2 (NLI-interacting factor 2) (Protein OS-4) , small C-terminal domain phosphatase 2 , CL468_1 , CL468_1(249) , CL468_1_ov , LTP , allergen Zea m 14 , non-specific lipid-transfer protein , propanoyl-CoA C-acyltransferase , sterol carrier protein X , NSL-TP , SCP-2 , SCP-X , SCP-chi , Sterol carrier protein 2, liver , sterol carrier protein-2 , SCPX , sterol carrier protein 2, liver , nonspecific lipid transfer protein

GENE ID SPECIES
52468 Mus musculus
542231 Zea mays
6342 Homo sapiens
479564 Canis lupus familiaris
397439 Sus scrofa
508918 Bos taurus
25541 Rattus norvegicus
396550 Gallus gallus
100008683 Oryctolagus cuniculus
100728738 Cavia porcellus
101116445 Ovis aries
20280 Mus musculus
Selected quality suppliers for anti-SCP2 (SCP2) Antibodies
Did you look for something else?