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STAG1 is a member of the SCC3 family and is expressed in the nucleus. Additionally we are shipping Stromal Antigen 1 Antibodies (85) and many more products for this protein.
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Data support the hypothesis that CTCF (show CTCF Proteins) and cohesin SA-1 have multiple roles in the regulation of gene expression during erythropoiesis.
TRF1 (show TERF1 Proteins) tethers SA1 within telomeric regions that SA1 transiently interacts with. SA1 and TRF1 (show TERF1 Proteins) together form longer DNA-DNA pairing tracts than with TRF1 (show TERF1 Proteins) alone, as revealed by atomic force microscopy imaging
Nuclear import and export signals of human cohesins SA1/STAG1 and SA2/STAG2 (show STAG2 Proteins) expressed in Saccharomyces cerevisiae.
Mutations in STAG1 is associated with acute myeloid leukemia (show BCL11A Proteins).
cohesin-SA1 and cohesin-SA2 (show STAG2 Proteins) participate in the DNA damage response
Rad21 (show RAD21 Proteins) binds to SA proteins through two SA-binding motifs on Rad21 (show RAD21 Proteins).
STAG1, a novel transcriptional target for p53 (show TP53 Proteins), mediates p53 (show TP53 Proteins)-dependent apoptosis, and might be a good candidate for next-generation gene therapy in cancer.
STAG1 (Scc3/SA1) subunit of cohesin interacts with the CCTC-binding factor CTCF (show CTCF Proteins) bound to the c-myc (show MYC Proteins) insulator element.
cohesin(SA1) and cohesin(SA2 (show STAG2 Proteins)) are differentially required for telomere and centromere cohesion, respectively.
reduced dosage of SA1 altered the architecture of the Reg (show KCNH2 Proteins) locus and decreased the expression of Reg (show KCNH2 Proteins) genes in the pancreas of SA1 heterozygous mice
This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase.
stromal antigen 1
, SCC3 homolog 1
, cohesin subunit SA-1
, nuclear protein stromal antigen 1
, cohesin subunit XSA1
, stromal antigen 1 homolog