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Structural Maintenance of Chromosomes 1B Proteins (SMC1B)

SMC1L2 belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis (3:Revenkova et al., 2001 [PubMed 11564881]).[supplied by OMIM, Mar 2008].. Additionally we are shipping SMC1B Antibodies (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SMC1B 27127 Q8NDV3
SMC1B 140557 Q920F6
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Top SMC1B Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

SMC1B Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Structural Maintenance of Chromosomes 1B (SMC1B) Interaction Partners

Human Structural Maintenance of Chromosomes 1B (SMC1B) interaction partners

  1. High SMC1B expression is associated with pancreatic cancer.

Mouse (Murine) Structural Maintenance of Chromosomes 1B (SMC1B) interaction partners

  1. Together with previous knowledge, three main functions of SMC1b have emerged, which have multiple consequences for spermatocyte biology.

  2. We report here evidence from the mouse that partial loss of gene function for either Smc1b or Rec8 (show REC8 Proteins) causes perturbations in the formation of the synaptonemal complex (SC) and affects both synapsis and recombination between homologs during meiotic prophase

  3. SMC1 beta-deficient mice of both sexes are sterile. Male meiosis is blocked in pachytene; female meiosis is highly error-prone but continues until metaphase II.

  4. E2F6 silences SMC1beta and STAG3 in somatic cells

  5. SMC1beta plays role in oogenesis.

  6. In addition to its role in sister chromatid cohesion, Smc1beta determines meiotic chromatin loop organization.

  7. A deletion of 16 nucleotides in exon 5 led to a frame-shift, which generated a stop codon at position 761 (amino acid 247) of the Smc1b cDNA in mutant mice.

  8. telomere structure protected from DNA rearrangements depends on SMC1beta.

SMC1B Protein Profile

Protein Summary

SMC1L2 belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis (3:Revenkova et al., 2001

Gene names and symbols associated with SMC1B

  • structural maintenance of chromosomes 1B (SMC1B)
  • structural maintenance of chromosomes 1B (Smc1b)
  • bK268H5 protein
  • bK268H5.5 protein
  • SMC-1B protein
  • SMC1beta protein
  • Smc1l2 protein

Protein level used designations for SMC1B

SMC protein 1B , SMC-1-beta , SMC-1B , SMC1 (structural maintenance of chromosomes 1, yeast)-like 1 , SMC1 structural maintenance of chromosomes 1-like 2 , mitosis-specific chromosome segregation protein like protein beta , structural maintenance of chromosomes protein 1B , structural maintenace of chromosomes 1B

GENE ID SPECIES
27127 Homo sapiens
140557 Mus musculus
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