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Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) ELISA Kits

SDHA encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. Additionally we are shipping Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) Antibodies (94) and Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SDHA SDHA 6389 P31040
SDHA 66945 Q8K2B3
Anti-Rat SDHA SDHA 157074 Q920L2
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Top Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) Interaction Partners

Human Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) interaction partners

  1. Combined blockade of CDK (show CDK4 ELISA Kits) and SDH (show SARDH ELISA Kits), both genetically and pharmaceutically, showed synergy and resulted in inhibited proliferation, migration, invasion and migration in A2780 cells Cyclin E (show CCNE1 ELISA Kits)-driven OvCa cells appeared addicted to glucose metabolism via TCA. Combined CDKi (show CDKN1C ELISA Kits) with modalities targeting TCA, like SDHA inhibition showed promising effects for this genotype.

  2. According to international guidelines, SDHB (show SDHB ELISA Kits), SDHC (show SDHC ELISA Kits), and SDHD (show SDHD ELISA Kits) genetic testing were performed in this patient, but not SDHA, which would have been prescribed only after surgery, in case of SDHA negative immunohistochemistry

  3. As a similar defect of succinate dehydrogenase is apparent in patient cell-derived cardiomyocytes, the authors conclude that these defects represent a molecular basis for the cardiac pathology in Barth syndrome (show TAZ ELISA Kits).

  4. our findings provide further evidence that patients with KIT/PDGFRA (show PDGFRA ELISA Kits) wild-type SDH (show SARDH ELISA Kits)-deficient GIST harboring SDHA mutations experience good survival outcomes

  5. This study strengthens the etiological association of SDH (show SARDH ELISA Kits) genes with pituitary neoplasia, renal tumorigenesis, and gastric gastrointestinal stromal tumors. Also, pancreatic neuroendocrine tumor falls within the SDH (show SARDH ELISA Kits)-related tumor spectrum.

  6. Three novel mutations in SDHA were found in patients presenting Leigh syndrome (LS) and/or leukodystrophy.

  7. Overall, 9 of the 34 patients with KIT/PDGFRA (show PDGFRA ELISA Kits) wild-type GIST carried mutations in one of the four subunits of the SDH (show SARDH ELISA Kits) complex (six patients in SDHA, two in SDHB (show SDHB ELISA Kits), one in SDHC (show SDHC ELISA Kits)

  8. SDH (show SARDH ELISA Kits) deficiency may promote tumorigenesis through accumulation of succinate and inhibition of dioxygenase enzymes. Inhibition of TET activity may, in turn, alter global DNA methylation (show HELLS ELISA Kits) and gene expression in SDH (show SARDH ELISA Kits)-deficient tumors.

  9. Data indicate that SDH5 is protected from mitochondrial LON protease (LONM)-mediated degradation in mitochondria by its stable interaction with SDHA, a state that is dysregulated in hereditary paraganglioma 2 (PGL2).

  10. Electron transport complex-II and manganese superoxide dismutase (MnSOD (show SOD2 ELISA Kits)) enzyme activities were decreased in obese compared with non-obese pregnant women.

Mouse (Murine) Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) interaction partners

  1. Tumor-derived FH and SDH (show SDS ELISA Kits) mutations accumulate fumarate and succinate, leading to enzymatic inhibition of multiple alpha-KG-dependent dioxygenases and consequent alterations of genome-wide histone and DNA methylation (show HELLS ELISA Kits).

  2. Data show that SdhA is required for preventing AIM2 (show AIM2 ELISA Kits) inflammasome activation.

  3. Data show that two subunits of complex II (succinate dehydrogenase (show SDHD ELISA Kits), or SDH (show SDS ELISA Kits)), SDHA and SDHB (show SDHB ELISA Kits), interacted specifically with SIRT3 (show SIRT3 ELISA Kits).

  4. Cocaine could inhibit the activities of ATPase (show DNAH8 ELISA Kits), LDH and SDH (show SDS ELISA Kits) in cultured splenocytes.

Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA) Antigen Profile

Antigen Summary

This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29.

Gene names and symbols associated with SDHA

  • Succinate dehydrogenase A (SdhA) antibody
  • succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA) antibody
  • succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (Sdha) antibody
  • succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (sdha) antibody
  • 1500032O14Rik antibody
  • 2310034D06Rik antibody
  • 4921513A11 antibody
  • C81073 antibody
  • CG17246 antibody
  • CMD1GG antibody
  • Dmel\\CG17246 antibody
  • Fp antibody
  • im:7141001 antibody
  • PGL5 antibody
  • scs-fp antibody
  • sdh antibody
  • SDH1 antibody
  • SDH2 antibody
  • Sdha antibody
  • sdha-b antibody
  • SDHF antibody
  • zgc:56051 antibody

Protein level used designations for SDHA

CG17246-PA , CG17246-PB , CG17246-PC , COMPLEX II: flavoprotein subunit , SUCCINYL COENZIME A SYNTHETASE FLAVOPROTEIN SUBUNIT , SdhA-PA , SdhA-PB , SdhA-PC , succinate dehydrogenase , succinate dehydrogenase A , succinate dehydrogenase flavoprotein , succinate dehydrogenase flavoprotein subunit , succinyl coenzyme A synthetase flavoprotein subunit , flavoprotein subunit of complex II , succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial , succinate dehydrogenase complex flavoprotein subunit , fp , succinate dehydrogenase complex subunit A , succinate dehydrogenase flavoprotein subunit A , succinate dehydrogenase Fp subunit , Flavoprotein subunit of complex II , Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial , mitochondrial succinate dehydrogenase complex subunit A , succinate dehydrogenase complex subunit A flavoprotein , flavoprotein subunit of complex II B , succinate dehydrogenase [ubiquinone] flavoprotein subunit B, mitochondrial

GENE ID SPECIES
37228 Drosophila melanogaster
6389 Homo sapiens
66945 Mus musculus
157074 Rattus norvegicus
393884 Danio rerio
281480 Bos taurus
395758 Gallus gallus
780433 Sus scrofa
380463 Xenopus laevis
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