Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD) ELISA Kits

SDHD encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. Additionally we are shipping Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein Antibodies (43) and Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein Proteins (13) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SDHD SDHD 6392 O14521
SDHD 66925 Q9CXV1
Anti-Rat SDHD SDHD 363061 Q6PCT8
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 0.066 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$606.32
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More ELISA Kits for Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein Interaction Partners

Human Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD) interaction partners

  1. promoter mutation seems to be a rare event in CM but SDHD lower expression might associate with worst prognostic features in CM

  2. role for GABPA (show GABPA ELISA Kits)/B1 as the critical ETS (show ETS1 ELISA Kits) transcription factors deregulating SDHD expression in the context of highly recurrent promoter mutations in melanoma.

  3. SDH (show SARDH ELISA Kits)-deficient gastrointestinal stromal tumors (GISTs) account for approximately 8% of gastric GISTs and are associated with a high rate of distant metastasis, regardless of conventional risk category.

  4. For classification, tumors were characterized by SDHA (show SDHA ELISA Kits), B, C, or D (SDHX) mutations and other genetic and epigenetic alterations, including presence of mutations in germline

  5. Heterozygous germline deletions of up to 104 kb in size were identified in SDHB (show SDHB ELISA Kits), SDHC (show SDHC ELISA Kits), SDHD and flanking genes in 20 paraganglioma-pheochromocytoma patients. The exact breakpoint could be determined in 16 paraganglioma-pheochromocytoma patients of which 15 were novel deletions

  6. our study reveals a novel mechanism of crosstalk amongst SDHD, PTEN and autophagy pathways and their potential roles in thyroid carcinogenesis

  7. According to international guidelines, SDHB (show SDHB ELISA Kits), SDHC (show SDHC ELISA Kits), and SDHD genetic testing were performed in this patient, but not SDHA (show SDHA ELISA Kits), which would have been prescribed only after surgery, in case of SDHA (show SDHA ELISA Kits) negative immunohistochemistry

  8. Mortality rates and survival in a Dutch cohort of SDHD variant carriers does not differ from that of the general Dutch population.

  9. Melanomas harbor recurrent SDHD promoter mutations, which occur primarily as C>T alterations in UV-exposed melanomas.

  10. Loss of SDH (show SARDH ELISA Kits) activity leads to changes in the metabolism of non-essential amino acids.

Pig (Porcine) Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD) interaction partners

  1. The expression and sequencing of SDHD and single nucleotide polymorphisms of the gene are reported.

Mouse (Murine) Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD) interaction partners

  1. the actual dependency of undifferentiated hematopoietic stem cells on mitochondrial function, we have performed an analysis of the hematopoiesis in a mouse mutant, named SDHD-ESR (show ESR1 ELISA Kits), with inducible deletion of the mitochondrial protein (show COX6B2 ELISA Kits)-encoding SdhD gene, is reported.

  2. Loss of SDH (show SDS ELISA Kits) activity leads to changes in the metabolism of non-essential amino acids.

  3. In mice with conditional knockout of Sdhd, we found that the Cdkn1a (show CDKN1A ELISA Kits) gene was up-regulated in kidney and adrenal. This gene encodes the cyclin-dependent kinase (show CDK1 ELISA Kits) inhibitor p21(WAF1/Cip1 (show CDKN1A ELISA Kits)), a factor implicated in cell cycle, senescence, and cancer.

  4. complete loss of SdhD is not sufficient to induce tumorigenesis in mice

  5. SDHD is required for the formation of a stable mitochondrial complex II, and it is selectively important for hypoxic pulmonary vasoconstriction of intra-acinar vessels.

  6. Knockout of Sdhd in the mouse does not result in a disease phenotype; H19 (show NCKAP1 ELISA Kits) may not be an initiator of PGL (show PGLS ELISA Kits)/PC tumorigenesis

  7. Mitochondrial Sdhd is required for early embryogenesis, and its partial deficiency results in persistent carotid body glomus cell activation with full responsiveness to cell hypoxia.

Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD) Antigen Profile

Antigen Summary

This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SDHD

  • succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD) antibody
  • succinate dehydrogenase complex, subunit D, integral membrane protein (Sdhd) antibody
  • 3110001M13Rik antibody
  • AVLL5809 antibody
  • C78570 antibody
  • CBT1 antibody
  • CII-4 antibody
  • CII4 antibody
  • CWS3 antibody
  • CybS antibody
  • PGL antibody
  • PGL1 antibody
  • PRO19626 antibody
  • QPs3 antibody
  • SDH4 antibody

Protein level used designations for SDHD

succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial , succinate-ubiquinone oxidoreductase cytochrome b small subunit , succinate-ubiquinone reductase membrane anchor subunit , Succinate dehydrogenase complex subunit D , Succinate-ubiquinone oxidoreductase cytochrome b small subunit , Succinate-ubiquinone reductase membrane anchor subunit , succinate dehydrogenase complex subunit D , CII-4 , QPs3 , cybS

GENE ID SPECIES
6392 Homo sapiens
479438 Canis lupus familiaris
100048954 Sus scrofa
281481 Bos taurus
66925 Mus musculus
363061 Rattus norvegicus
419793 Gallus gallus
101111485 Ovis aries
100172275 Pongo abelii
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