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anti-Succinate Dehydrogenase Complex Assembly Factor 2 (Sdhaf2) Antibodies

Sdhaf2 encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Additionally we are shipping Sdhaf2 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Sdhaf2 54949 Q9NX18
Sdhaf2 66072 Q8C6I2
Sdhaf2 361726 Q5RJQ7
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Top anti-Sdhaf2 Antibodies at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Chicken Un-conjugated EIA, WB Western blot analysis of SDHAF2 in rat liver tissue lysate with SDHAF2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Chicken Un-conjugated IHC (p), ELISA, WB   50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Chicken Un-conjugated ELISA, WB Western blot analysis of SDHAF2 in rat liver tissue lysate with SDHAF2 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide. 0.1 mg Log in to see 2 to 3 Days
$330.00
Details
Human Chicken Un-conjugated IHC (p), ELISA, WB   50 μg Log in to see 11 to 13 Days
$478.80
Details
Human Chicken Un-conjugated ELISA, WB   0.1 mg Log in to see 6 to 9 Days
$477.75
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p)   0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB   0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 8 to 9 Days
$588.50
Details

Sdhaf2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,

Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-Sdhaf2 Antibodies

  1. Human Polyclonal Sdhaf2 Primary Antibody for EIA, WB - ABIN1450092 : Burnichon, Brière, Libé, Vescovo, Rivière, Tissier, Jouanno, Jeunemaitre, Bénit, Tzagoloff, Rustin, Bertherat, Favier, Gimenez-Roqueplo: SDHA is a tumor suppressor gene causing paraganglioma. in Human molecular genetics 2010 (PubMed)
    Show all 2 references for ABIN1450092

More Antibodies against Sdhaf2 Interaction Partners

Human Succinate Dehydrogenase Complex Assembly Factor 2 (Sdhaf2) interaction partners

  1. Autosomal dominant susceptibility for Paraganglioma is modified by imprinting and mutations in the SDHAF2 gene cause Paragangliomas only when the mutation is inherited from father.

  2. Loss of heterozygosity was found in more than 50 % of the von Hippel-Lindau-associated pheochromocytomas, and was correlated with a significant decrease (p < 0.05) in both SDHAF2 and SDHD (show SDHD Antibodies) mRNA expression, which may be suggestive of a pathogenic role.

  3. New mutation found in SDHAF2 gene in pheochromocytoma/paraganglioma patients.

  4. Data indicate that SDH5 is protected from mitochondrial LON (show LONP1 Antibodies) (LONM)-mediated degradation in mitochondria by its stable interaction with SDHA (show SDHA Antibodies), a state that is dysregulated in hereditary paraganglioma 2 (PGL2).

  5. Data indicate that succinate dehydrogenase (show SDHA Antibodies) 5 (SDH5) functions as a critical protein in regulating epithelial-mesenchymal transition (EMT (show ITK Antibodies)) by modulating the glycogen synthase kinase (GSK)-3beta (show GSK3b Antibodies)-beta-catenin (show CTNNB1 Antibodies) signaling pathway.

  6. Studies indicate that mutations in the mitochondrial complex II structural subunit genes SDHB (show SDHB Antibodies), SDHC (show SDHC Antibodies) and SDHD (show SDHD Antibodies) and the regulatory subunit gene SDHAF2 in many paraganglioma families.

  7. Studies indicate that an array of tumor syndromes caused by complex II-associated mutations in genes SDHA (show SDHA Antibodies), SDHB (show SDHB Antibodies), SDHC (show SDHC Antibodies), SDHD (show SDHD Antibodies), SDHAF1 (show SDHAF1 Antibodies) and SDHAF2 have been identified over a decade.

  8. Studies indicate that the flavinylation factor Sdh5 (SDHAF2) provided insight into the possible mechanism associated with Sdh1 (SDHA (show SDHA Antibodies)) flavinylation.

  9. We established the SDHAF2 mutation status of PGL2 family members

  10. Somatic mutations of the SDHAF2 tumor suppressor gene are unlikely to frequently contribute to parathyroid tumor development in sporadic primary hyperparathyroidism.

Sdhaf2 Antigen Profile

Protein Summary

This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Mutations in this gene are associated with paraganglioma.

Gene names and symbols associated with Sdhaf2

  • succinate dehydrogenase complex assembly factor 2 (SDHAF2) antibody
  • succinate dehydrogenase complex assembly factor 2 (LOC100353725) antibody
  • succinate dehydrogenase complex assembly factor 2 (Sdhaf2) antibody
  • succinate dehydrogenase complex assembly factor 2 (sdhaf2) antibody
  • 0610038F07Rik antibody
  • AA407634 antibody
  • AW049997 antibody
  • C11orf79 antibody
  • C14H11orf79 antibody
  • PGL2 antibody
  • RGD1309216 antibody
  • SDH5 antibody
  • wu:fj30e04 antibody
  • zgc:163000 antibody

Protein level used designations for Sdhaf2

succinate dehydrogenase complex assembly factor 2 , succinate dehydrogenase assembly factor 2, mitochondrial , SDH assembly factor 2 , Protein EMI5 homolog, mitochondrial , succinate dehydrogenase subunit 5, mitochondrial , hSDH5

GENE ID SPECIES
476065 Canis lupus familiaris
693401 Macaca mulatta
100173895 Pongo abelii
100353725 Oryctolagus cuniculus
54949 Homo sapiens
66072 Mus musculus
767983 Bos taurus
361726 Rattus norvegicus
569482 Danio rerio
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