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Sulfatase Modifying Factor 1 (SUMF1) ELISA Kits

SUMF1 encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Additionally we are shipping SUMF1 Antibodies (54) and SUMF1 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SUMF1 285362 Q8NBK3
SUMF1 58911 Q8R0F3
Anti-Rat SUMF1 SUMF1 362409  
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Top SUMF1 ELISA Kits at antibodies-online.com

Showing 3 out of 7 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.064 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Mouse
  96 Tests Log in to see 11 to 13 Days
$875.60
Details
Cow
  96 Tests Log in to see 11 to 13 Days
$1,029.60
Details

Top referenced SUMF1 ELISA Kits

  1. Human SUMF1 ELISA Kit for Sandwich ELISA - ABIN418547 : Bhattacharyya, Tobacman: Hypoxia reduces arylsulfatase B activity and silencing arylsulfatase B replicates and mediates the effects of hypoxia. in PLoS ONE 2012 (PubMed)

More ELISA Kits for SUMF1 Interaction Partners

Human Sulfatase Modifying Factor 1 (SUMF1) interaction partners

  1. SUMF1 catalyses a monooxygenase type of reaction.

  2. This detailed clinical description and follow-up of a cohort of patients, together with the molecular characterisation of their underlying defects, contribute to improved knowledge of multiple sulfatase deficiency.

  3. MSD (show MESDC2 ELISA Kits) presenting in the newborn period with hypotonia, apnoea, cyanosis and rolling eyes, hepato-splenomegaly and deafness. This patient was compound heterozygous for two so far undescribed SUMF1 mutations (c.191C > A; p.S64X and c.818A > G; p.D273G

  4. The complete kinetic parameters for both forms of FGE are described, along with a proposed mechanism for FGE catalysis that accounts for the copper-dependent activity.

  5. A novel missense mutation & an insertional truncating mutation in SUMF1 gene causing nultiple sulphatase deficiency.

  6. furin (show FURIN ELISA Kits)-mediated processing of FGE during secretion is a physiological means of higher eukaryotic cells to regulate FGE activity upon exit from the endoplasmic reticulum

  7. Phenotypic outcome in Multiple Sulfatase Deficiency depends on both residual FGE activity as well as protein stability.

  8. This study identified genetic variation of SUMF1 in genes associated with in vivo glutamate (show GRIN1 ELISA Kits) measured using 1H magnetic resonance spectroscopic imaging in the grey matter of patients with multiple sclerosis.

  9. mutational analysis of SUMF1 in 20 Multiple sulfatase deficiency patients of different ethnic origin

  10. characterization of the human Calpha (show PRKACA ELISA Kits)-formylglycine-generating enzyme

Mouse (Murine) Sulfatase Modifying Factor 1 (SUMF1) interaction partners

  1. Sumf1(-/-) astrocytes failed to support the survival and function of wild-type cortical neurons, suggesting a non-cell autonomous mechanism for neurodegeneration.

  2. Sumf1 controls hematopoietic stem progenitor cell differentiation and hematopoietic lineage development through FGF and Wnt (show WNT2 ELISA Kits) signaling.

  3. Sumf1 is indispensable for sulfatase activation in mice and mammals, differently from bacteria, have a single sulfatase modification system

SUMF1 Antigen Profile

Antigen Summary

This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SUMF1

  • sulfatase modifying factor 1 (SUMF1) antibody
  • sulfatase modifying factor 1 (Sumf1) antibody
  • AA543204 antibody
  • AAPA3037 antibody
  • AI463102 antibody
  • AI851573 antibody
  • FGE antibody

Protein level used designations for SUMF1

C-alpha-formylglycine-generating enzyme 1 , FGly-generating enzyme , sulfatase-modifying factor 1 , sulfatase-modifying factor

GENE ID SPECIES
285362 Homo sapiens
58911 Mus musculus
362409 Rattus norvegicus
536435 Bos taurus
484681 Canis lupus familiaris
100514188 Sus scrofa
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