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anti-Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14) Antibodies

The protein encoded by ST14 is an epithelial-derived, integral membrane serine protease. Additionally we are shipping Suppression of Tumorigenicity 14 (Colon Carcinoma) Proteins (7) and Suppression of Tumorigenicity 14 (Colon Carcinoma) Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ST14 6768 Q9Y5Y6
ST14 19143 P56677
ST14 114093  
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Top anti-Suppression of Tumorigenicity 14 (Colon Carcinoma) Antibodies at antibodies-online.com

Showing 10 out of 91 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from A549 cells, using ST14 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using ST14 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ST14 Antibody Titration: 0.2-1 ug/mlPositive Control: THP-1 cell lysate WB Suggested Anti-ST14  Antibody Titration: 0.2-1 µg/mL  Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged ST14 is approximately 1ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunofluorescence analysis of A549 cells, using ST14 Antibody. The picture on the right is treated with the synthesized peptide. Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Mouse Rabbit Un-conjugated IHC (p), WB ST14 Antibody (C-term R841) (ABIN652185) western blot analysis in mouse liver tissue lysates (35 µg/lane).This demonstrates the ST14 antibody detected the ST14 protein (arrow). ST14 Antibody (C-term) (ABIN652185)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged ST14 is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details

ST14 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Suppression of Tumorigenicity 14 (Colon Carcinoma) Antibodies

  1. Human Monoclonal ST14 Primary Antibody for ELISA - ABIN520529 : Sasaroli, Gimotty, Pathak, Hammond, Kougioumtzidou, Katsaros, Buckanovich, Devarajan, Sandaltzopoulos, Godwin, Scholler, Coukos: Novel surface targets and serum biomarkers from the ovarian cancer vasculature. in Cancer biology & therapy 2011 (PubMed)

  2. Human Polyclonal ST14 Primary Antibody for IF, ELISA - ABIN1534221 : Bhatt, Erdjument-Bromage, Tempst, Craik, Moasser: Adhesion signaling by a novel mitotic substrate of src kinases. in Oncogene 2005 (PubMed)

More Antibodies against Suppression of Tumorigenicity 14 (Colon Carcinoma) Interaction Partners

Human Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14) interaction partners

  1. Given that matriptase-1 participates in terminal KC differentiation, its absence in psoriatic skin lesions indicates that this contributes to the barrier disturbances in this disease.

  2. Novel findings reveal a new paradigm in matriptase activation involving PDGF-D (show PDGFD Antibodies)-specific signal transduction leading to extracellular acidosis.

  3. Maritriptase is required for pro-HGF/c-Met signaling and cell proliferation in breast cancer cells.

  4. Matriptase inhibition by HAI-2 (show SPINT2 Antibodies) requires the translocation of HAI-2 (show SPINT2 Antibodies) to the cell surface, a process which is observed in some breast cancer cells but not in mammary epithelial cells.

  5. prostate cancer cell invasion is stimulated by a rapid but sustained increase in Src (show SRC Antibodies) activity, mediated non-genomically by cytoplasmic AR, leading to rapid activation and shedding of the laminin protease Matriptase

  6. Report potent/specific inhibition of matriptase by the cyclic microprotein MCoTI-II.

  7. Matriptase expression correlates with tumour progression and invasive capability in oral squamous cell carcinoma

  8. Matriptase can act as a cellular sensor of the chemical environment of the cell that allows the cell to respond to and protect itself from changes in the chemical milieu.

  9. It presents evidence that matriptase efficiently cleaves the HR1 portion of gp41 into a 22-residue chemotactic peptide MAT-1 (show MAT1A Antibodies), the sequence of which is highly conserved across HIV-1 clades.

  10. Dysregulated pericellular proteolysis as a result of unregulated matriptase expression with limited HAI-1 (show SPINT1 Antibodies) may contribute to the pathological characteristics of several human B-cell lymphomas.

Mouse (Murine) Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14) interaction partners

  1. The proliferation impairment in matriptase-deficient breast cancer cells is caused by their inability to initiate activation of the c-Met signalling pathway in response to fibroblast-secreted pro-HGF (show HGF Antibodies).

  2. Matriptase is a critical promoter of late stages of squamous cell carcinoma progression and induces pro-tumorigenic chemokine (show CCL1 Antibodies) and cytokine release, and inflammatory cell accumulation in established tumors.

  3. Data show that proteinase-activated receptor (PAR)-2-dependent inflammatory signaling as an essential component of matriptase-mediated and potentiation of ras-mediated oncogenesis.

  4. HAI-1 (show SPINT1 Antibodies) regulates the activity of activated matriptase, whereas HAI-2 (show SPINT2 Antibodies) has an essential role in regulating prostasin (show PRSS8 Antibodies)-dependent matriptase zymogen activation.

  5. Our results reveal unexpected complementary roles of matriptase-prostasin (show PRSS8 Antibodies)- and PAR-2 (show F2RL1 Antibodies)-dependent proteolytic signaling in the establishment of placental epithelial barrier function and overall embryonic survival.

  6. These findings suggest that TGF-beta (show TGFB1 Antibodies) induces epithin/PRSS14 shedding by mediating translocation of epithin/PRSS14 sheddase, TACE (show ADAM17 Antibodies), to the membrane.

  7. Matriptase deletion initiates a Sjogren's syndrome-like disease in mice.

  8. Matriptase is required for the active form of hepatocyte growth factor (show HGF Antibodies) induced Met, focal adhesion kinase and protein kinase B (show AKT1 Antibodies) activation on neural stem/progenitor cell motility.

  9. ST14 expression is downregulated in colitis.

  10. St14 is a critical tumor-suppressor gene in the mouse gastrointestinal tract and adds matriptase to the expanding list of pericellular proteases with tumor-suppressive functions

Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14) Antigen Profile

Protein Summary

The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

Gene names and symbols associated with ST14

  • ST14 (LOC100101609) antibody
  • suppression of tumorigenicity 14 (colon carcinoma) (ST14) antibody
  • suppression of tumorigenicity 14 (colon carcinoma) (st14-a) antibody
  • suppression of tumorigenicity 14 (colon carcinoma) (St14) antibody
  • Epithin antibody
  • hai antibody
  • matriptase antibody
  • mCAP3 antibody
  • mt-sp1 antibody
  • mtsp1 antibody
  • Prss14 antibody
  • snc19 antibody
  • st14 antibody
  • st14a antibody
  • tadg15 antibody
  • tmprss1 antibody
  • Tmprss14 antibody
  • XMT-SP1 antibody

Protein level used designations for ST14

membrane-type serine protease 1 , prostamin , serine protease 14 , serine protease TADG-15 , suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin) , suppressor of tumorigenicity 14 protein , tumor associated differentially expressed gene 15 protein , tumor-associated differentially-expressed gene 15 protein , matriptase a , suppression of tumorigenicity 14 (colon carcinoma) a , suppressor of tumorigenicity 14 protein homolog , suppressor of tumorigenicity protein 14 , matriptase/MT-SP1 , protease, serine, 14 (epithin) , matriptase , membrane-type serine protease

GENE ID SPECIES
100101609 Oryctolagus cuniculus
6768 Homo sapiens
394363 Xenopus laevis
767617 Bos taurus
19143 Mus musculus
114093 Rattus norvegicus
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