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Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. Additionally we are shipping Suppressor of Ty 16 Proteins (2) and many more products for this protein.
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SPT16 and SSRP1 are critically involved in the regulation of leaf growth, flowering time and seed production, and interact with HUB1/2.
FACT is required for TOP1 (show TOP1 Antibodies) binding to H3K4me3 at non-B DNA containing chromatin for the site-specific cleavage.
The mouse Supt16h/Fact140 gene, encoding part of the FACT chromatin transcription complex, maps close to Tcra and is highly expressed in thymus
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (Probable).
FACT complex subunit SPT16
, facilitates chromatin transcription complex subunit SPT16
, global transcription factor group C 102
, global transcription factor group C protein 102
, hypothetical protein
, FACT 140 kDa subunit
, chromatin-specific transcription elongation factor 140 kDa subunit
, suppressor of Ty 16 homolog