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Synovial sarcomas occur most frequently in the extremities around large joints. Additionally we are shipping SS18L1 Proteins (5) and many more products for this protein.
Showing 10 out of 35 products:
Cow (Bovine) Polyclonal SS18L1 Primary Antibody for WB - ABIN2786440
de Bruijn, Geurts van Kessel: Common origin of the human synovial sarcoma associated SS18 and SS18L1 gene loci. in Cytogenetic and genome research 2006
calcium-responsive transactivator and certain other amyotrophic lateral sclerosis-linked proteins share several features implicated in amyotrophic lateral sclerosis pathogenesis
This study demonistrated that CREST mutations inhibited activity-dependent neurite outgrowth in primary neurons, and CREST associated with the ALS (show IGFALS Antibodies) protein FUS (show FUS Antibodies).
A synovial sarcoma of classic morphology contained a novel t(20;X) SS18L1(strong homology to SS18 (show SS18 Antibodies) on Ch20)/SSX1 (show SSX1 Antibodies) fusion transcript in which nucleotide 1216 (exon 10) of SS18L1 was fused in-frame with nucleotide 422 (exon 6) of SSX1 (show SSX1 Antibodies).
SS18 (show SS18 Antibodies) and SS18L1 genes map within co-linear DNA segments that may have evolved through a relatively recent genomic duplication event.
Data suggest that co-activation of CREST and CBP (CREB-binding protein (show CREBBP Antibodies)) enhances signaling between p-Creb (show CREB1 Antibodies)/AP-1 (show JUN Antibodies) and p-HIF-1 (show HIF1A Antibodies)/HRE resulting in up-regulation of Glut3 (glucose transporter type 3 (show SLC2A3 Antibodies)); here, stimulus was cell hypoxia.
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X\;18)(p11.2\;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L1 gene is homologous to SS18.
synovial sarcoma translocation gene on chromosome 18-like 1
, SS18-like protein 1
, calcium-responsive transactivator
, ss18-like protein 1
, SYT homolog 1
, calcium-responsive transcription coactivator