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Tachykinin 3 Proteins (TAC3)

TAC3 encodes a member of the tachykinin family of secreted neuropeptides. Additionally we are shipping Tachykinin 3 Antibodies (50) and Tachykinin 3 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse TAC3 TAC3 21334 P55099
TAC3 6866 Q9UHF0
Rat TAC3 TAC3 29191 P08435
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Top Tachykinin 3 Proteins at

Showing 3 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
Human Un-conjugated   5 μg Log in to see 6 Days

TAC3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Tachykinin 3 (TAC3) Interaction Partners

Rhesus Monkey Tachykinin 3 (TAC3) interaction partners

  1. Influence of age and 17beta-estradiol on kisspeptin, neurokinin B, and prodynorphin (show PDYN Proteins) gene expression in the arcuate-median eminence.

Mouse (Murine) Tachykinin 3 (TAC3) interaction partners

  1. Data show that estrogen receptor alpha (ERalpha (show ESR1 Proteins)) in tachykinin 2 (show TAC1 Proteins) protein (Tac2 (show TAC1 Proteins)) neurons typically restrains pubertal onset and hypothalamic reproductive drive.

  2. Tac2 (show TAC1 Proteins)-/- females had delays in sexual maturation, with time to vaginal opening and first estrus occurring later than controls. However, cycling recovered in adulthood and Tac2 (show TAC1 Proteins)-/- females were fertile, although they produced fewer pups per litter.

  3. Increased Tac2 (show TAC1 Proteins) expression, through a stress-induced PTSD-like model, or following lentiviral CeA (show CEA Proteins) overexpression, are sufficient to enhance fear consolidation.

  4. Data suggest that activation of neurokinin 3 and kappa-opioid receptors (NK3R (show TACR3 Proteins) and KOR (show OPRK1 Proteins)) excites and inhibits kisspeptin, neurokinin B (NKB), and dynorphin (KNDy neurons).

  5. NKB could directly regulate secretion from NK3R-expressing GnRH neurons.

  6. Tac2 (show TAC1 Proteins) homozygous null mice responded normally to a series of algogenic (pain-inducing) and pruritic (itch-inducing) stimuli.

  7. Preprotachykinin (show TAC1 Proteins) (PPT)-B genes are expressed in uterine cells, oocytes, ovaries and embryos from mice, and may play a role in female reproductive function.

Human Tachykinin 3 (TAC3) interaction partners

  1. mutations in TAC (show IL2RA Proteins) and TACR3 (show TACR3 Proteins) are not a common cause for ICPP.

  2. Colocalization experiments provided evidence for the presence of cocaine- and amphetamine-regulated transcript (show CARTPT Proteins) (CART) in KP-immunoreactive (IR) and perikarya and in KP-IR and NKB-IR axon varicosities.

  3. Amino acid substitution A63P in TAC3 gene was statistically associated with the puberty onset time in Chinese girls.

  4. SP may influence the KP and NKB secretory output via additional autocrine/paracrine mechanisms or regulate GnRH neurosecretion directly.

  5. Copper can enter cultured astrocytoma cells and subsequently open plasma membrane calcium channels, but when bound to NKB, copper ion uptake is inhibited.

  6. Expression of the gene encoding NKB (TAC3) is up-regulated 20-fold in leiomyomas, compared with matched myometrium.

  7. Rare variants in the TAC3 and TACR3 (show TACR3 Proteins) genes were identified in patients with central pubertal disorders and loss-of-function variants of TACR3 (show TACR3 Proteins) were associated with the normosmic IHH (show IHH Proteins) phenotype.

  8. these immunohistochemical data suggest an aging-related moderate enhancement in central NKB signaling.

  9. NKB neurons in the arcuate nucleus do not synthesize detectable amounts of kisspeptin and dynorphin in young male humans. These data call for a critical use of the KNDy neuron terminology when referring to the pulse generator of the hypothalamus

  10. NKB/NK(3)R and kisspeptin/KISS1R are present in female peripheral reproductive tissues with colocalization of both systems in some non-neuronal cell populations of the human female genital tract.

Pig (Porcine) Tachykinin 3 (TAC3) interaction partners

Tachykinin 3 (TAC3) Protein Profile

Protein Summary

This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with Tachykinin 3 Proteins (TAC3)

  • tachykinin 3 (TAC3)
  • tachykinin 2 (Tac2)
  • tachykinin 3 (Tac3)
  • HH10 protein
  • NKB protein
  • NKNB protein
  • PPT-B protein
  • PRO1155 protein
  • Tac2 protein
  • Tac3 protein
  • ZNEUROK1 protein

Protein level used designations for Tachykinin 3 Proteins (TAC3)

tachykinin 3 , neurokinin B , preprotachykinin B , tachykinin 3 (neuromedin K, neurokinin beta) , PPT-B , neurokinin 2 , neurokinin A , neurokinin B-like protein Zneurok1 , neurokinin alpha , neuromedin L , neuropeptide K , preprotachykinin-B , substance K , tachykinin-3 , gamma tachykinin 3 , neuromedin K , tachykinin 2 , Neuromedin-K , neurokinin , neurokinin-B , neurokinin B, neuromedin K , tachykinin 3, neurokinin beta

443213 Ovis aries
713978 Macaca mulatta
746748 Pan troglodytes
21334 Mus musculus
6866 Homo sapiens
29191 Rattus norvegicus
492314 Sus scrofa
281513 Bos taurus
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