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Tachykinin Receptor 3 Proteins (TACR3)

TACR3 belongs to a family of genes that function as receptors for tachykinins. Additionally we are shipping Tachykinin Receptor 3 Antibodies (90) and Tachykinin Receptor 3 Kits (32) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TACR3 6870 P29371
TACR3 21338 P47937
Rat TACR3 TACR3 24808 P16177
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Top Tachykinin Receptor 3 Proteins at

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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.25 mg Log in to see 49 to 54 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.5 mg Log in to see 49 to 54 Days

TACR3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine) ,

More Proteins for Tachykinin Receptor 3 (TACR3) Interaction Partners

Human Tachykinin Receptor 3 (TACR3) interaction partners

  1. mutations in TAC (show IL2RA Proteins) and TACR3 are not a common cause for ICPP.

  2. None of the 4 single polymorphisms studied in TACR3 are linked directly to puberty onset time, but A63P in TAC3 (show TAC3 Proteins) is statistically associated with precocious puberty.

  3. Elevated CRP (show CRP Proteins) is likely a pathogenic factor contributing to preeclampsia by binding to phosphocholinated neurokinin B and preferentially activating NK3R.

  4. data indicate that GPR54 and TACR3 gene mutations are not a frequent cause of ICPP. The identified A/G synonymous SNP (dbSNP ID: rs10407968) located in exon 1 of the gene is not likely to have a pathogenic role in exon splicing

  5. Studies indicate the molecular mechanisms by which NK3R mutations cause GnRH deficiency.

  6. Expression of the gene encoding TACR3 is significantly up-regulated in leiomyomas, compared with matched myometrium.

  7. Rare variants in the TAC3 (show TAC3 Proteins) and TACR3 genes were identified in patients with central pubertal disorders and loss-of-function variants of TACR3 were associated with the normosmic IHH (show IHH Proteins) phenotype.

  8. Data suggest that mutations in TACR3 and GNRHR (show GNRHR Proteins) are the most common causative mutations in normosmic idiopathic hypogonadotropic hypogonadism in families in Turkey.

  9. NKB/NK(3)R and kisspeptin/KISS1R are present in female peripheral reproductive tissues with colocalization of both systems in some non-neuronal cell populations of the human female genital tract.

  10. The gonadotropin axis dysfunction associated with nCHH due to TAC3 (show TAC3 Proteins)/TACR3 mutations is related to a low GnRH (show GNRH1 Proteins) pulsatile frequency leading to a low frequency of alpha-subunit (show POLG Proteins) pulses and to an elevated FSH (show BRD2 Proteins)/LH ratio.

Mouse (Murine) Tachykinin Receptor 3 (TACR3) interaction partners

  1. Data suggest that activation of neurokinin 3 and kappa-opioid receptors (NK3R and KOR (show OPRK1 Proteins)) excites and inhibits kisspeptin, neurokinin B (NKB), and dynorphin (KNDy neurons).

  2. NKB (show TAC3 Proteins)-NK3R signaling plays a role in pubertal maturation; its alterations may contribute to pubertal disorders linked to metabolic stress and negative energy balance.

  3. although capable of fertility, Tacr3-deficient mice have central reproductive defects

  4. neurokinin 3 receptor activation in the median preoptic nucleus modulates body temperature

  5. Tachykinin NK3 receptor genes are expressed in uterine cells, oocytes, ovaries and embryos from mice, and may play a role in female reproductive function.

  6. The co-expression of NK-3R and NMDA/AMPA (show GRIA3 Proteins) receptor subunits in the nigral neurons has provided a structural basis for functional modulation of neuronal glutamate (show GRIN1 Proteins) receptors by neurokinin-3.

  7. In neurokinin 1 receptor knockout retinas no major changes were detected: neurokinin 3 receptor mRNA levels as well as substance P (show TAC1 Proteins) and neurokinin 3 receptor immunostainings were similar to wild types.

  8. these results support a role for the NK(3) receptor in performance of operant tasks and in spatial learning but not in working memory

  9. Together, these results support a role for the NK3 receptor in reactivity to dopaminergic stimuli, but the lack of robust changes indicates that the sensitivity to dopamine may be activity-dependent or benign in nature.

Guinea Pig Tachykinin Receptor 3 (TACR3) interaction partners

  1. Evidence for tachykinin NK3 receptors-triggered peptide YY release from isolated guinea-pig distal colon

  2. [MePhe]-NKB and senktide caused bronchoconstriction in guinea pig through activation of the tachykinin NK-receptors but the tachykinin NK- and/or NK-receptors are also involved in the response.

Tachykinin Receptor 3 (TACR3) Protein Profile

Protein Summary

This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B.

Gene names and symbols associated with Tachykinin Receptor 3 Proteins (TACR3)

  • tachykinin receptor 3 (TACR3)
  • tachykinin receptor 3 (Tacr3)
  • HH11 protein
  • NK-3R protein
  • Nk3r protein
  • Nkr protein
  • Nmkr protein
  • Tac3r protein
  • TAC3RL protein

Protein level used designations for Tachykinin Receptor 3 Proteins (TACR3)

tachykinin receptor 3 , neuromedin-K receptor-like , NK-3 receptor , neurokinin B receptor , neurokinin beta receptor , neuromedin-K receptor , Nk3 receptor , neurokinin 3 receptor , neuromedin K receptor , NK-3R , Neuromedin K receptor (Neurokinin B/Tachikin 3) , tachikin receptor 3 , NKR , neurokinin receptor subtype NK3 , neurokinin-3 receptor , tachykinin neurokinin-3 receptor

100393973 Callithrix jacchus
100544805 Meleagris gallopavo
100605722 Nomascus leucogenys
6870 Homo sapiens
21338 Mus musculus
24808 Rattus norvegicus
100135627 Cavia porcellus
768993 Gallus gallus
403814 Canis lupus familiaris
100521983 Sus scrofa
404136 Bos taurus
100008721 Oryctolagus cuniculus
101121604 Ovis aries
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