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Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) ELISA Kits

Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Additionally we are shipping Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase Antibodies (58) and Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TNKS 8658 O95271
TNKS 21951 Q6PFX9
Anti-Rat TNKS TNKS 290794  
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Top Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.106 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
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Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
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Monkey
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$770.00
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Chicken
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$770.00
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Rabbit
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$770.00
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Mouse
  96 Tests Log in to see 11 to 13 Days
$875.60
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Human
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$875.60
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More ELISA Kits for Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase Interaction Partners

Human Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) interaction partners

  1. HCMV modulates the activity of TNKS to induce Axin1 (show AXIN1 ELISA Kits), resulting in inhibition of the beta-catenin (show CTNNB1 ELISA Kits) pathway.

  2. Data show that E7449 represents a dual Poly(ADP-ribose) Polymerase 1 (show PARP1 ELISA Kits)/2 and tankyrase 1/2 inhibitor which has the advantage of targeting Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling addicted tumors.

  3. TNKS1 SNPs (rs11991621 rs10503380, and rs7015700) were associated with non-small cell lung cance risk, whereas rs6601328 and rs12541709 inversely associated with risk

  4. Tankyrase inhibition is a potential therapeutic approach for treating a subgroup HCC (show FAM126A ELISA Kits) with aberrant WNT (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling pathway.

  5. TNKS1 is recruited to DNA lesions by MDC1 (show MDC1 ELISA Kits) and promotes homologous recombination in response to DNA double strand breaks.

  6. Copy number deletion on TNKS was associated with a 1.37-fold decreased risk for osteoarthritis.

  7. tankyrase-mediated PARsylation is promoted by nutritional energy stimulated NAD+ in insulinoma (show RPS15 ELISA Kits) cells

  8. Data indicate that tankyrase (Tnks) inhibitors impact telomere length maintenance independently of their affects on Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling.

  9. We demonstrate for the first time that tankyrase inhibition triggers reduced cell growth and differentiation of OS cells

  10. Studies show a significant interaction of IWR1 with acidic and polar residues (Asp (show ASIP ELISA Kits) and Tyr (show TYR ELISA Kits)) in the hydrophobic region at the induced pocket of TNKS1/TNKS2 (show TNKS2 ELISA Kits). These two residues are the key for the mechanism of inhibition of TNKS proteins.

Mouse (Murine) Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) interaction partners

  1. analyses also reveal the structural basis for TNKS substrate recruitment, and shed light on the overall structure of TNKS that should help in developing specific inhibitors of Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling

  2. Data show that Tnks1 and 2 are broadly expressed during mouse development and are essential during kidney and lung development. In the kidney, blockage of tankyrase activity phenocopies the effect of blocking production of all Wnt (show WNT2 ELISA Kits) ligands.

  3. Collectively, our data suggest that GSK3 contributes to mitotic tankyrase phosphorylation.

  4. insulin (show INS ELISA Kits)-stimulated insulin-responsive aminopeptidase (show LNPEP ELISA Kits) translocation remained intact despite substantial GLUT4 (show SLC2A4 ELISA Kits) knockdown

  5. tankyrase1 is a poly(ADP-ribose) polymerase (show PARP1 ELISA Kits) with roles in telomere length control by the TRF1 (show TERF1 ELISA Kits) component of the shelterin complex

  6. Tankyrase 1 is essential but redundant for mouse embryonic development

  7. Tankyrase-deficient mice exhibit increases in energy expenditure, fatty acid oxidation, and insulin (show INS ELISA Kits)-stimulated glucose utilization.

Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS) Antigen Profile

Antigen Summary

Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles.

Gene names and symbols associated with TNKS

  • si:ch211-155m12.3 (si:ch211-155m12.3) antibody
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (TNKS) antibody
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (Tnks) antibody
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (tnks) antibody
  • 4930554K12Rik antibody
  • AI662855 antibody
  • ARTD5 antibody
  • C86528 antibody
  • D130072O21Rik antibody
  • mTNKS1 antibody
  • PARP-5a antibody
  • PARP5A antibody
  • PARPL antibody
  • pART5 antibody
  • TANK1 antibody
  • tankyrase-1 antibody
  • TIN1 antibody
  • TINF1 antibody
  • TNKS1 antibody
  • wu:fe02c12 antibody

Protein level used designations for TNKS

fe02c12 , tankyrase 1 , ADP-ribosyltransferase diphtheria toxin-like 5 , TANK1 , TNKS-1 , TRF1-interacting ankyrin-related ADP-ribose polymerase , poly [ADP-ribose] polymerase 5A , tankyrase I , tankyrase-1 , TRF1-interacting ankyrin-related ADP-ribose polymerase 1

GENE ID SPECIES
567533 Danio rerio
8658 Homo sapiens
21951 Mus musculus
100036993 Xenopus laevis
374252 Gallus gallus
475603 Canis lupus familiaris
535030 Bos taurus
290794 Rattus norvegicus
100153228 Sus scrofa
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