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The protein encoded by TSPAN5 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Additionally we are shipping Tetraspanin 5 Antibodies (44) and many more products for this protein.
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Endothelial Tspan5- and Tspan17-ADAM10 (show ADAM10 Proteins) complexes may regulate inflammation by maintaining normal VE-cadherin (show CDH5 Proteins) expression and promoting T lymphocyte transmigration.
two TspanC8-specific motifs in the large extracellular domain of Tspan5 that are important for ADAM10 (show ADAM10 Proteins) interaction and exit from the endoplasmic reticulum. One of the anti-Tspan5 mAbs does not recognize Tspan5 associated with ADAM10 (show ADAM10 Proteins), providing a convenient way to measure the fraction of Tspan5 not associated with ADAM10 (show ADAM10 Proteins).
Tspan-5 and Tspan-10, are up-regulated during osteoclast differentiation and knockdown of their expression dramatically inhibits osteoclastogenesis
The level of Tspan-5 expression might be important for distinct phases of neuronal maturation.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
, transmembrane 4 superfamily member 9
, tetraspan 5
, tetraspan NET-4
, tetraspan TM4SF
, transmembrane 4 superfamily, member 8
, tetraspanin Tspan-5