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TPK1 encodes a protein, that exists as a homodimer, which catalyzes the conversion of thiamine to thiamine pyrophosphate. Additionally we are shipping TPK1 Antibodies (31) and TPK1 Kits (6) and many more products for this protein.
Showing 10 out of 20 products:
Human TPK1 Protein expressed in Escherichia coli (E. coli) - ABIN667678
Nosaka, Onozuka, Kakazu, Hibi, Nishimura, Nishino, Abe: Isolation and characterization of a human thiamine pyrophosphokinase cDNA. in Biochimica et biophysica acta 2001
Show all 2 references for ABIN667678
Human TPK1 Protein expressed in Escherichia coli (E. coli) - ABIN2181858
Bellyei, Szigeti, Boronkai, Szabo, Bene, Janaky, Barna, Sipos, Minik, Kravjak, Ohmacht, Melegh, Zavodszky, Than, Sumegi, Bohn, Than: Cloning, sequencing, structural and molecular biological characterization of placental protein 20 (PP20)/human thiamin pyrophosphokinase (hTPK). in Placenta 2005
Show all 2 references for ABIN2181858
stress response, and/or fecundity of isp-1(qm150) Mit mutants relative to wild-type animals
These findings demonstrate that the genes involved in dictating thiamine homeostasis, such as SLC19A2, SLC25A19 and TPK-1, were significantly up-regulated in clinical tissues and breast cancer cell lines.
Mutation analysis of TPK1 uncovered three missense, one splice-site, and one frameshift mutation resulting in decreased TPK protein levels
findings indicate the importance of the Sp1 transcription factor (show SP1 Proteins) cis (show CISH Proteins)-element in regulating the human thiamin pyrophosphokinase gene (hTPK1) gene expression
Genomic variations in either the fetal or maternal TPK1 gene could contribute to variability of birth weight in normal humans.
Three-dimensional structure of thiamine pyrophosphokinase crystallized from an equilibrium substrate/product mixture shows clear electron density for pyrithiamine pyrophosphate bound in the enzyme active site.
This gene encodes a protein, that exists as a homodimer, which catalyzes the conversion of thiamine to thiamine pyrophosphate. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
thiamin pyrophosphokinase 1
, hypothetical protein
, thiaminepyrophosphokinase 1
, placental protein 20
, thiamine diphosphokinase
, thiamine kinase
, thiamine pyrophosphokinase
, thiamine pyrophosphokinase 1