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Thiopurine S-Methyltransferase (TPMT) ELISA Kits

TPMT encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Additionally we are shipping TPMT Antibodies (92) and TPMT Proteins (24) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TPMT 22017 O55060
TPMT 7172 P51580
TPMT 690050  
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Top TPMT ELISA Kits at antibodies-online.com

Showing 5 out of 10 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.127 ng/mL 1.56-100 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
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Cow
  96 Tests Log in to see 11 to 13 Days
$1,029.60
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Mouse
  96 Tests Log in to see 11 to 13 Days
$1,029.60
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Rat
  96 Tests Log in to see 11 to 13 Days
$1,029.60
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Dog
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$1,095.60
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More ELISA Kits for TPMT Interaction Partners

Mouse (Murine) Thiopurine S-Methyltransferase (TPMT) interaction partners

  1. These findings support the notion that germline polymorphisms in Tpmt affect not only host tissue toxicity but also antitumor effectiveness.

  2. suggestion that differential mouse TPMT activity is due to variation in mRNA expression

Human Thiopurine S-Methyltransferase (TPMT) interaction partners

  1. structure-function relationships of TPMT

  2. The TPMT promoter region may serve as a pharmacogenomic biomarker when introducing thiopurine therapy

  3. The most frequently occurring nonfunctional TPMT allele in Croatian population is TPMT*3A. Variant genotypes were statistically significantly more common in Crohn's disease subgroup than in ulcerative colitis subgroup.

  4. Association of TPMT polymorphisms with overall azathioprine-induced adverse drug reactions, bone marrow toxicity and gastric intolerance, but not with hepatotoxicity (meta-analysis).

  5. association of TPMT polymorphisms with overall thiopurine-induced adverse drug reactions

  6. Identification of TPMT variants and subsequent dose reduction reduces hematologic events during thiopurine treatment of inflammatory bowel disease.

  7. TPMT*3c mutant allele was associated with azathioprine side effects (leukopenia, alopecia) in Chinese systemic lupus erythematosus patients.

  8. refinements in risk stratification and treatment have reduced the influence of TPMT genotype on treatment outcome in a contemporary protocol.

  9. We report on the presence of the TPMT*3C and *3A mutant alleles in the Libyan population. Therefore, monitoring the patients to be treated with doses of thiopurine drugs for TPMT variants is worthwhile to avoid the development of severe myelosuppression.

  10. this paper shows that the influence of TPMT and COMT (show COMT ELISA Kits) on the development of cisplatin-induced hearing loss may be less important than previously suggested.

TPMT Antigen Profile

Antigen Summary

This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.

Gene names and symbols associated with TPMT

  • thiopurine S-methyltransferase (tpmt) antibody
  • zgc:101684 (zgc:101684) antibody
  • thiopurine S-methyltransferase (tpm) antibody
  • thiopurine S-methyltransferase (MCA0794) antibody
  • thiopurine S-methyltransferase (Pnap_4948) antibody
  • thiopurine S-methyltransferase (Hhal_1383) antibody
  • thiopurine S-methyltransferase (TK90_1044) antibody
  • thiopurine S-methyltransferase (Slit_1144) antibody
  • thiopurine S-methyltransferase (Tint_0842) antibody
  • Thiopurine S-methyltransferase (Fbal_3334) antibody
  • thiopurine S-methyltransferase (Celly_3188) antibody
  • thiopurine S-methyltransferase (Weevi_1737) antibody
  • Thiopurine S-methyltransferase (Psefu_2696) antibody
  • Thiopurine S-methyltransferase (Metme_3860) antibody
  • thiopurine methyltransferase (Tpmt) antibody
  • thiopurine S-methyltransferase (TPMT) antibody
  • thiopurine S-methyltransferase (Tpmt) antibody
  • AW106912 antibody
  • MGC84277 antibody
  • NHLRC1 antibody

Protein level used designations for TPMT

thiopurine S-methyltransferase , Thiopurine S-methyltransferase , S-adenosyl-L-methionine:thiopurine S-methyltransferase , thiopurine methyltransferase , NHL repeat containing 1

GENE ID SPECIES
447769 Xenopus laevis
573111 Danio rerio
1168449 Shewanella oneidensis MR-1
3104309 Methylococcus capsulatus str. Bath
4685796 Polaromonas naphthalenivorans CJ2
4711327 Halorhodospira halophila SL1
8806802 Thioalkalivibrio sp. K90mix
8891817 Sideroxydans lithotrophicus ES-1
9151573 Thiomonas intermedia K12
9772187 Ferrimonas balearica DSM 9799
10265228 Cellulophaga lytica DSM 7489
10282995 Weeksella virosa DSM 16922
10657285 Pseudomonas fulva 12-X
10673875 Methylomonas methanica MC09
22017 Mus musculus
7172 Homo sapiens
403536 Canis lupus familiaris
511644 Bos taurus
690050 Rattus norvegicus
493759 Felis catus
100034066 Equus caballus
100009411 Oryctolagus cuniculus
471863 Pan troglodytes
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