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TYMP encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. Additionally we are shipping Thymidine Phosphorylase Proteins (46) and Thymidine Phosphorylase Kits (21) and many more products for this protein.
Showing 10 out of 116 products:
Human Monoclonal Thymidine Phosphorylase Primary Antibody for IHC (p), WB - ABIN114827
Fox, Westwood, Moghaddam, Comley, Turley, Whitehouse, Bicknell, Gatter, Harris: The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium. in British journal of cancer 1996
Show all 4 references for ABIN114827
Human Polyclonal Thymidine Phosphorylase Primary Antibody for EIA, IHC (p) - ABIN359550
Jinfeng, Kimura, Sakurai, Moriya, Mizutani, Hirai: Prognostic role of angiogenesis and its correlations with thymidine phosphorylase and p53 expression in ductal adenocarcinoma of the pancreas. in Hepato-gastroenterology 2007
Show all 2 references for ABIN359550
Human Polyclonal Thymidine Phosphorylase Primary Antibody for IHC (p), WB - ABIN391460
Stenman, Sahlin, Dumanski, Hagiwara, Ishikawa, Miyazono, Collins, Heldin: Regional localization of the human platelet-derived endothelial cell growth factor (ECGF1) gene to chromosome 22q13. in Cytogenetics and cell genetics 1992
Sphingosine 1-phosphate-induced IL-8 (show IL8 Antibodies) gene expression is mainly regulated via S1PR(1 (show S1PR1 Antibodies)), and its secretion is regulated through S1PR(2 (show S1PR2 Antibodies)) receptor subtype.
multiple lines of evidence demonstrate that S1PR1 (show S1PR1 Antibodies) signaling sets the sensitivity of pDC (show PNKD Antibodies) amplification of IFN responses, thereby blunting pathogenic immune responses
The results indicate that sphingosine 1-phosphate is involved in the migration of precursor T-cell lymphoblastic leukemia-lymphoma blasts in vitro, which is dependent on S1P1 (show S1PR1 Antibodies) expression.
Overexpression of miR148a or inhibition of S1PR1 (show S1PR1 Antibodies) suppressed SKOV3 cell migration and invasion, while restoration of S1PR1 (show S1PR1 Antibodies) expression reversed the suppressive effect of miR148a upregulation on SKOV3 cell migration and invasion.
the ability of ApoM (show APOM Antibodies)(+)HDL (show HSD11B1 Antibodies) to act as a biased agonist on S1P1 (show S1PR1 Antibodies) inhibits vascular inflammation, which may partially explain the cardiovascular protective functions of HDL (show HSD11B1 Antibodies).
S1P (show MBTPS1 Antibodies) receptor modulation reduces leukocyte migration across the endothelial barrier
SGPL1 (show SGPL1 Antibodies) ratio correlated with increased cellular sphingosine-1-phosphate (S1P (show MBTPS1 Antibodies)), and S1P (show MBTPS1 Antibodies) correlated with drug resistance (IC50).
Within lymphoid follicles, the S1P1 (show S1PR1 Antibodies) distribution pattern is complementary to that of CCR7 (show CCR7 Antibodies)/CXCR4 (show CXCR4 Antibodies), with strong immunoreactivity tightly restricted to mantle zone B cells. This may play a role in B-cell migration toward the S1p (show MBTPS1 Antibodies)-enriched follicle center.
Ponesimod, a selective S1P1 (show S1PR1 Antibodies) receptor modulator, causes small, dose-dependent QT prolongation.
rapid reduction of endothelial cell surface expression of S1PR1 (show S1PR1 Antibodies) subsequent to Y143 phosphorylation is a crucial mechanism of modulating S1PR1 (show S1PR1 Antibodies) signaling, and hence the endothelial barrier repair function of S1P (show MBTPS1 Antibodies).
data identify TYMP as an astrocyte-derived permeability factor, and suggest TYMP and VEGFA (show VEGFA Antibodies) together promote blood-brain barrier breakdown.
TYMP participates in multiple platelet signaling pathways and regulates platelet activation and thrombosis. Targeting TYMP might be a novel antiplatelet and antithrombosis therapy.
Thymidine phosphorylase and UPP1 (show UPP1 Antibodies) double knockout mice showed increased thymidine and deoxyuridine in tissues and developed encephalopathy.
This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified.
, Thymidine phosphorylase
, S1P receptor 1
, S1P receptor Edg-1
, endothelial differentiation G-protein coupled receptor 1
, endothelial differentiation, sphingolipid G-protein-coupled receptor, 1
, sphingosine 1-phosphate receptor 1
, sphingosine 1-phosphate receptor EDG1
, sphingosine 1-phosphate receptor Edg-1
, endothelial cell growth factor 1 (platelet-derived)
, platelet derived growth factor, endothelial cell