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Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) Proteins (TFAP2C)

The protein encoded by TFAP2C is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. Additionally we are shipping Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) Antibodies (79) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat TFAP2C TFAP2C 362280  
TFAP2C 7022 Q92754
TFAP2C 21420 Q61312
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Top Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TFAP2C Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) Proteins

  1. Human TFAP2C Protein expressed in Escherichia coli (E. coli) - ABIN2005457 : Woodfield, Hitchler, Chen, Domann, Weigel: Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure. in Clinical cancer research : an official journal of the American Association for Cancer Research 2009 (PubMed)
    Show all 3 references for ABIN2005457

More Proteins for Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) Interaction Partners

Human Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) interaction partners

  1. Higher TFAP2C protein expression correlates with poor overall survival after 10 years of diagnosis in ERalpha (show ESR1 Proteins)-positive breast cancer.

  2. TFAP2C has an important role in regulated luminal-specific genes and may be a viable therapeutic target in breast cancer.

  3. ShRNA knockdown of AP-2gamma in neuroblastoma (show ARHGEF16 Proteins) cells results in significant inhibit of cell proliferation.

  4. Knockdown of TFAP2C or RET (show RET Proteins) inhibited activation of ERK (show EPHB2 Proteins) and AKT (show AKT1 Proteins) in MCF-7 cells. Knockdown of TFAP2C, which controls ER (estrogen receptor (show ESR1 Proteins)) and RET (show RET Proteins), had a greater effect on cell growth than either RET (show RET Proteins) or ER alone.

  5. role for TFAP2C in melanoma via its regulation of ECM1 (show ECM1 Proteins)

  6. TFAP2C amplification and overexpression represents a genetic dependency in ERBB2 (show ERBB2 Proteins)+ve breast cancer.

  7. TFAP2C regulates expression of the RET proto-oncogene (show RET Proteins) through five AP-2 (show GTF3A Proteins) regulatory sites in the RET (show RET Proteins) promoter.

  8. Results demonstrate that TFAP2C regulates the expression of GPX1 (show GPX1 Proteins), which influences the redox state and sensitivity to oxidative stress induced (show SQSTM1 Proteins) by peroxides.

  9. ESDN and AP-2g expression is lower in thick melanomas, it is associated with unfavourable histo-pathological parameters (increased vascularity, vascular invasion and mitoses) and correlates with a shorter DFS (show FST Proteins) like for AP-2a.

  10. demonstrated that while TFAP2C and Myc (show MYC Proteins) can downregulate the CDKN1A promoter independently, KDM5B (show KDM5B Proteins) acts as a corepressor dependent on the other two proteins

Zebrafish Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) interaction partners

  1. Redundant activities of Tfap2a (show TFAP2A Proteins) and Tfap2c are required for neural crest induction and development of other non-neural ectoderm derivatives in zebrafish embryos.

Xenopus laevis Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) interaction partners

  1. Expression of TFAP2beta (show TFAP2B Proteins) and TFAP2gamma genes in Xenopus laevis.

Cow (Bovine) Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) interaction partners

  1. Tfap2c expression is altered in early preimplantation SCNT embryos, which may have developmental consequences resulting from genes influenced by Tfap2c, but expression was not different at the blastocyst stage and in placentomes.

Mouse (Murine) Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) interaction partners

  1. TFAP2C in trophoblasts controls proliferation by repressing Cdkn1a (show CDKN1A Proteins) and activating the MAPK (show MAPK1 Proteins) pathway, further supporting differentiation of glycogen (show GYS1 Proteins) cells by activating the AKT (show AKT1 Proteins) pathway

  2. these findings indicate that a reduction in the gene dosage of placental Tfap2c leads to morphological changes in the labyrinth at midgestation

  3. TFAP2C regulates tumorigenesis, cell growth and survival in HER2 (show ERBB2 Proteins)-amplified breast cancer through transcriptional regulation of EGFR (show EGFR Proteins).

  4. Transcription factor AP-2gamma induces early Cdx2 (show CDX2 Proteins) expression and represses HIPPO signaling to specify the trophectoderm lineage.

  5. we characterize the cis (show CISH Proteins)-regulatory organization of a large genomic locus consisting of Tfap2c and Bmp7 (show BMP7 Proteins). We show that this locus is structurally partitioned into two distinct domains by the constitutive action of a discrete transition zone

  6. mice with a heterozygous deletion of the TFAP2C target gene Nanos3 (show NANOS3 Proteins) are also prone to develop teratomas. These data highlight TFAP2C as a critical and dose-sensitive regulator of germ cell fate.

  7. Tcfap2c is not required for Oct4 (show POU5F1 Proteins) silencing in mouse blastocysts, but may be necessary for the maintenance of Oct4 (show POU5F1 Proteins) expression during the 8 cell-to-morula transition.

  8. critical roles for AP-2 (show TFAP2A Proteins) activity in retinogenesis, delineating the overlapping expression patterns of Tcfap2a (show TFAP2A Proteins), Tcfap2b (show TFAP2B Proteins), and Tcfap2c in the neural retina, and revealing a redundant requirement for Tcfap2a (show TFAP2A Proteins) and Tcfap2b (show TFAP2B Proteins) in horizontal and amacrine cell development

  9. An important role for TCFAP2C, SMARCA4 (show SMARCA4 Proteins), and EOMES (show EOMES Proteins) in TS cell self-renewal.

  10. Data suggest that Tcfap2c and Cdx2 (show CDX2 Proteins) cooperate to override the pluripotency program and establish the extraembryonic trophoblast maintenance program in murine embryos.

Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) Protein Profile

Protein Summary

The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.

Gene names and symbols associated with TFAP2C

  • transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) (tfap2c)
  • transcription factor AP-2 gamma (TFAP2C)
  • transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) (TFAP2C)
  • transcription factor ap-2 gamma (Smp_157840)
  • transcription factor AP-2 gamma (LOC100345121)
  • transcription factor AP-2 gamma (Tfap2c)
  • transcription factor AP-2, gamma (Tfap2c)
  • AA409384 protein
  • Ap-2.2 protein
  • ap-2g protein
  • AP2-GAMMA protein
  • AP2gamma protein
  • ERF1 protein
  • hAP-2g protein
  • Stra2 protein
  • Tcfap2c protein
  • tfa2pc protein
  • TFAP2C protein
  • TFAP2G protein
  • tfap2gamma protein
  • wu:fb48g05 protein
  • wu:fb49c04 protein
  • zgc:92088 protein

Protein level used designations for TFAP2C

transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) , transcription factor AP-2 gamma , transcription factor ap-2 gamma , transcription factor AP-2 gamma-like , activating enhancer binding protein 2 gamma , activator protein 2 gamma , activating enhancer-binding protein 2 gamma , estrogen receptor factor 1 , transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma) , transcription factor ERF-1 , fb48g05 , fb49c04 , AP2-gamma , stimulated by retinoic acid gene 2

GENE ID SPECIES
496506 Xenopus (Silurana) tropicalis
705384 Macaca mulatta
747174 Pan troglodytes
8343150 Schistosoma mansoni
100345121 Oryctolagus cuniculus
100400638 Callithrix jacchus
100470360 Ailuropoda melanoleuca
100554893 Anolis carolinensis
362280 Rattus norvegicus
7022 Homo sapiens
494033 Danio rerio
398790 Xenopus laevis
419327 Gallus gallus
485941 Canis lupus familiaris
100144525 Sus scrofa
511317 Bos taurus
21420 Mus musculus
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