anti-Transcription Factor E3 (TFE3) Antibodies

The microphthalmia transcription factor/transcription factor E (MITF-TFE) family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors includes four family members: MITF, TFE3, TFEB and TFEC. Additionally we are shipping TFE3 Kits (6) and TFE3 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TFE3 7030 P19532
TFE3 317376  
TFE3 209446 Q64092
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Top anti-TFE3 Antibodies at antibodies-online.com

Showing 10 out of 99 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TFE3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TFE3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from K562/A549 cells, using TFE3 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TFE3 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated IP, WB Western blot analysis of TFE3. Lysate from WI-38 cells was probed with anti- TFE3 (clone G138-312) at concentrations of 1.0 (lane 1), 0.5 (lane 2), and 0.25 myg/ml (lane 3). TFE3 is identified as a band of 50 kDa. 0.1 mg Log in to see 6 to 8 Days
$206.39
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$306.90
Details
Cow Goat Un-conjugated EIA, WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated WB TFE3 Antibody (C-term)  western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the TFE3 Antibody detected the TFE3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), SimWes, WB Western Blot: Transcription factor E3 Antibody  - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II. Western Blot: Transcription factor E3 Antibody  - Analysis in human cell line U-2 OS. 0.1 mL Log in to see 7 to 9 Days
$439.69
Details
Human Rabbit Un-conjugated IF, WB TFE3 Antibody (N-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TFE3 Antibody detected the TFE3 protein (arrow). TFE3 Antibody (N-term)  western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the TFE3 antibody detected the TFE3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details

TFE3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)
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Top referenced anti-TFE3 Antibodies

  1. Human Monoclonal TFE3 Primary Antibody for IP, WB - ABIN967449 : Beckmann, Su, Kadesch: TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif. in Genes & development 1990 (PubMed)
    Show all 5 references for 967449

  2. Human Polyclonal TFE3 Primary Antibody for ICC, IF - ABIN4361935 : Hong, Oh, Valera, Baba, Schmidt, Linehan: Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization. in PLoS ONE 2011 (PubMed)
    Show all 5 references for 4361935

  3. Human Polyclonal TFE3 Primary Antibody for WB - ABIN871655 : Weterman, Wilbrink, Geurts van Kessel: Fusion of the transcription factor TFE3 gene to a novel gene, PRCC, in t(X;1)(p11;q21)-positive papillary renal cell carcinomas. in Proceedings of the National Academy of Sciences of the United States of America 1997 (PubMed)
    Show all 2 references for 871655

  4. Cow (Bovine) Polyclonal TFE3 Primary Antibody for WB - ABIN2777945 : Geller, Argani, Adeniran, Hampton, De Marzo, Hicks, Collins: Translocation renal cell carcinoma: lack of negative impact due to lymph node spread. in Cancer 2008 (PubMed)

  5. Human Polyclonal TFE3 Primary Antibody for ELISA, WB - ABIN184740 : Henthorn, Stewart, Kadesch, Puck: The gene encoding human TFE3, a transcription factor that binds the immunoglobulin heavy-chain enhancer, maps to Xp11.22. in Genomics 1992 (PubMed)

  6. Human Polyclonal TFE3 Primary Antibody for IHC, ELISA - ABIN1533650 : Clark, Lu, Sidhar, Parker, Gill, Smedley, Hamoudi, Linehan, Shipley, Cooper: Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma. in Oncogene 1997 (PubMed)

More Antibodies against TFE3 Interaction Partners

Human Transcription Factor E3 (TFE3) interaction partners

  1. we analyze 60 Xp11 translocation cancers by fluorescence in situ hybridization using custom bacterial artificial chromosome probes to establish their TFE3 fusion gene partner

  2. These results show that ASPL (show ASPSCR1 Antibodies)-TFE3 regulates cell cycle progression and induces cellular senescence by up-regulating p21 (show CDKN1A Antibodies) expression.

  3. RBM10 (show RBM10 Antibodies)-TFE3 is a recurrent gene fusion in Xp11 translocation renal cell carcinoma (show MOK Antibodies).

  4. Case Report: melanotic PEComa of the sinonasal mucosa with NONO (show NONO Antibodies)-TFE3 fusion.

  5. Xp11 translocation renal cell carcinomas with RBM10 (show RBM10 Antibodies)-TFE3 gene fusion demonstrating melanotic features and overlapping morphology with t(6;11) RCC (show XRCC1 Antibodies).

  6. The essential parts of the Golgi stress response from the perspective of the organelle autoregulation. The pathways of the mammalian Golgi stress response have been identified, specifically the TFE3 pathway.

  7. Female patients with Xp11.2 renal cell carcinoma (show MOK Antibodies) in adults exhibit a high incidence compared to male, but not in children. Comparable clinical characteristics including incidence of distant and lymphatic metastases, tumor stage and prognosis is presented between male and female as well as between children and adults

  8. RBM10 (show RBM10 Antibodies)-TFE3 fusion variant (from chromosome X paracentric inversion), therefore, appears to be a recurrent molecular event in Xp11.2 RCCs. RBM10 (show RBM10 Antibodies)-TFE3 fusion should be added in the list of screened fusion transcripts in targeted molecular diagnostic multiplex RT-PCR

  9. The recently identified group of Xp11.2 translocation/TFE (show TCF4 Antibodies) gene fusion renal cell carcinomas (Xp11.2/TFE (show TCF4 Antibodies) RCC (show XRCC1 Antibodies)) affect approximately 15 % of patients under 45 years old with renal cell carcinoma (show MOK Antibodies).

  10. Akt (show AKT1 Antibodies) modulates nuclear translocation of TFE3.

Mouse (Murine) Transcription Factor E3 (TFE3) interaction partners

  1. Tfe3 overexpression in HSPCs impaired long-term hematopoietic reconstitution in vivo, recapitulating the Flcn (show FLCN Antibodies) KO phenotype, and supporting the notion that abnormal activation of Tfe3 contributes to the Flcn (show FLCN Antibodies) KO phenotype. Flcn (show FLCN Antibodies) KO mice develop an acute histiocytic hyperplasia in multiple organs, suggesting a novel function for Flcn (show FLCN Antibodies) in macrophage development

  2. TFEB (show TFEB Antibodies) and TFE3 are novel components of the integrated stress response

  3. Tfe3 is a critical transcription factor that regulates Pgc-1alpha (show PPARGC1A Antibodies) gene expression in myotubes

  4. A conditional expression in mice of the fusion gene ASPSCR1 (show ASPSCR1 Antibodies)-TFE3 from human alveolar soft part sarcoma (ASPS (show DARS Antibodies)) generated a model that recapitulates the human tumor histologically and by expression profile.

  5. Data from transgenic mice suggest Tfe3 controls lipid metabolism in adipose tissue (white, WAT; brown, BAT (show BAAT Antibodies)); TFE3 appears to be regulated by diet; up-regulation of TFE3 may inhibit expression of lipolysis genes in WAT and thermogenesis genes in BAT (show BAAT Antibodies).

  6. These findings indicated that TFE3 has a regulatory role in myoblast differentiation, and that transcriptional suppression of myogenin (show MYOG Antibodies) expression may be part of the mechanism of action.

  7. Machinery regulating exit of embryonic stem cells from pluripotency is ill defined; Flcn (show FLCN Antibodies) with its interaction partners Fnip1 (show FNIP1 Antibodies) and Fnip2 (show FNIP2 Antibodies) drives differentiation by restricting nuclear localization and activity of the bHLH transcription factor (show MSGN1 Antibodies) Tfe3.

  8. TFE3 and Galpha (show SUCLG1 Antibodies)(16) are up-regulated under pathologic conditions and are involved in a novel mechanism of transcriptional regulation via the relocalization and activation of Galpha (show SUCLG1 Antibodies)(16).

  9. FLCN (show FLCN Antibodies) tumor suppressor gene inactivation induces TFE3 transcriptional activity by increasing its nuclear localization

  10. TFE3 and TFEB (show TFEB Antibodies) regulate E-cadherin (show CDH1 Antibodies) and WT1 (show WT1 Antibodies) expression

TFE3 Antigen Profile

Protein Summary

The microphthalmia transcription factor/transcription factor E (MITF-TFE) family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors includes four family members: MITF, TFE3, TFEB and TFEC. The TEF3 protein encoded by this gene activates transcription through binding to the muE3 motif of the immunoglobulin heavy-chain enhancer. The TFEC protein forms heterodimers with the TEF3 protein and inhibits TFE3-dependent transcription activation. The TEF3 protein interacts with transcription regulators such as E2F3, SMAD3, and LEF-1, and is involved in TGF-beta-induced transcription, playing important roles in cell growth, proliferation, and osteoclast and macrophage differentiation. The TFE3 protein also activates hepatic IRS-2 gene, and induces hexokinase II (HK2) and insulin-induced gene 1 (INSIG1)\; it participates in insulin signaling and could be a therapeutic target for diabetes. This gene is also involved in chromosomal translocations, resulting in different fusion gene products in papillary renal cell carcinomas and alveolar soft part sarcomas, such as PRCC-TFE3, RCC17-TFE3, PSF-TFE3, NonO (p54nrb)-TFE3 and ASPL-TFE3.

Gene names and symbols associated with TFE3

  • transcription factor binding to IGHM enhancer 3 (TFE3) antibody
  • transcription factor binding to IGHM enhancer 3 (Tfe3) antibody
  • transcription factor binding to IGHM enhancer 3 (tfe3) antibody
  • transcription factor E3 (Tfe3) antibody
  • bHLHe33 antibody
  • F830016E06Rik antibody
  • RCCP2 antibody
  • RCCX1 antibody
  • RGD1559642 antibody
  • Tcfe3 antibody
  • Tfe-3 antibody
  • TFEA antibody

Protein level used designations for TFE3

class E basic helix-loop-helix protein 33 , transcription factor E family, member A , transcription factor E3 , transcription factor for IgH enhancer , transcription factor for immunoglobulin heavy-chain enhancer 3

GENE ID SPECIES
7030 Homo sapiens
491872 Canis lupus familiaris
520800 Bos taurus
317376 Rattus norvegicus
495043 Xenopus laevis
209446 Mus musculus
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