TFE3 antibody (AA 101-150)

Catalog No. ABIN1533650

The Rabbit Polyclonal anti-TFE3 antibody (ABIN1533650) specifically detects TFE3 in WB, ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for TFE3 antibody (AA 101-150) (ABIN1533650)

Target: TFE3 (Transcription Factor E3 (TFE3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFE3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TFE3 Antibody

Binding Specificity: AA 101-150

Purpose: TFE3 Antibody

Specificity: TFE3 Polyclonal Antibody detects endogenous levels of TFE3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TFE3. AA range:101-150

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TFE3

Target: TFE3 (Transcription Factor E3 (TFE3))

Alternative Name: TFE3

Background:

Synonyms: TFE3, BHLHE33, Transcription factor E3, Class E basic helix-loop-helix protein 33, bHLHe33

Background: This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],

Gene Name: TFE3

Protein Name: Transcription factor E3

Molecular Weight: 61 kDa

Gene ID: 7030

OMIM: 314310

UniProt: P19532