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The protein encoded by TBL1XR1 has sequence similarity with members of the WD40 repeat-containing protein family. Additionally we are shipping TBL1XR1 Kits (15) and TBL1XR1 Proteins (5) and many more products for this protein.
Showing 10 out of 69 products:
Human Monoclonal TBL1XR1 Primary Antibody for IF, WB - ABIN396109
Rose, Behm, Drgon, Johnson, Uhl: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. in Molecular medicine (Cambridge, Mass.) 2010
Show all 5 references for ABIN396109
Human Polyclonal TBL1XR1 Primary Antibody for EIA, WB - ABIN955106
Parker, An, Barber, Case, Davies, Konn, Stewart, Wright, Griffiths, Ross, Moorman, Hall, Irving, Harrison, Strefford: The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR1. in Genes, chromosomes & cancer 2008
Show all 3 references for ABIN955106
Human Monoclonal TBL1XR1 Primary Antibody for IF, IHC (p) - ABIN566377
Keutgens, Shostak, Close, Zhang, Hennuy, Aussems, Chapelle, Viatour, Gothot, Fillet, Chariot: The repressing function of the oncoprotein BCL-3 requires CtBP, while its polyubiquitination and degradation involve the E3 ligase TBLR1. in Molecular and cellular biology 2010
These finding suggested that TBLR1 is likely to be a potential prognostic indicator and therapeutic target for HCC (show FAM126A Antibodies) and that TBLR1 may be implicated in EMT (show ITK Antibodies) of HCC (show FAM126A Antibodies) cells.
Results show that upregulation of TBL1XR1 induces Nasopharyngeal Carcinoma cells resistance to cisplatin by activating the NF-kappaB (show NFKB1 Antibodies) pathway.
that TBL1XR1 haploinsufficiency can cause intellectual disability with a recognizable dysmorphism, without necessarily causing autistic behavior.
TBLR1 plays a key role in the development and progression of breast cancer cells via cyclin D1 (show CCND1 Antibodies)-transactivation and activation of the beta-catenin (show CTNNB1 Antibodies) signaling pathway.
Patient with TBL1XR1 mutation [c.209 G>A (p.Gly70Asp)] leading to West syndrome with Rett-like features, together with autistic features was reported.
results demonstrated that TBL1XR1 induced lymphangiogenesis and lymphatic metastasis in esophageal squamous cell carcinoma via upregulation of VEGF-C (show VEGFC Antibodies), and may represent a novel prognostic biomarker and therapeutic target for patients with ESCC.
data indicate that loss of TBL1XR1 is a novel driver of glucocorticoid resistance in ALL and that epigenetic therapy may have future application in restoring drug sensitivity at relapse.
The TBLR1 protein may be a prognostic marker in cervical cancer and play an important role in the invasion and metastasis of human cervical cancer
Stable ectopic expression of TBLR1 leads to androgen-dependent growth suppression of prostate cancer cells by selective activation of androgen-regulated genes associated with differentiation and growth suppression but not cell proliferation.
Our study provides new insights into the molecular tumorigenesis of PCNSL and identifies novel genetic alterations in this disease, especially MYD88 (show MYD88 Antibodies) and TBL1XR1 mutations activating the NF-kappaB (show NFKB1 Antibodies) signaling pathway.
The cell autonomous transcriptional activity of TBLR1 controls multiple beta-adrenoceptor and postreceptor checkpoints in white adipocytes, thereby coordinating an integrated response of cAMP-dependent free fatty acid (FFA) mobilization.
TBLR1 and TBL1 (show TBL1X Antibodies) have roles in specific nuclear receptor-mediated gene activation events
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation.
transducin (beta)-like 1 X-linked receptor 1
, F-box-like/WD repeat-containing protein TBL1XR1
, f-box-like/WD repeat-containing protein TBL1XR1-like
, transducin (beta)-like 1X-linked receptor 1
, nuclear receptor co-repressor/HDAC3 complex subunit
, TBL1-related protein 1
, nuclear receptor corepressor/HDAC3 complex subunit TBLR1
, transducin beta-like 1X-related protein 1
, F-box-like/WD repeat protein TBL1XR1