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TFRC encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. Additionally we are shipping Transferrin Receptor (p90, CD71) Proteins (27) and Transferrin Receptor (p90, CD71) Kits (24) and many more products for this protein.
Showing 10 out of 438 products:
Mouse (Murine) Monoclonal TFRC Primary Antibody for FACS, IHC (fro) - ABIN111981
Brekelmans, van Soest, Leenen, van Ewijk: Inhibition of proliferation and differentiation during early T cell development by anti-transferrin receptor antibody. in European journal of immunology 1994
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Mouse (Murine) Monoclonal TFRC Primary Antibody for FACS, IHC (fro) - ABIN111980
Brekelmans, van Soest, Voerman, Platenburg, Leenen, van Ewijk: Transferrin receptor expression as a marker of immature cycling thymocytes in the mouse. in Cellular immunology 1995
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Mouse (Murine) Monoclonal TFRC Primary Antibody for FACS - ABIN118246
Lesley, Hyman, Schulte, Trotter: Expression of transferrin receptor on murine hematopoietic progenitors. in Cellular immunology 1984
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Human Monoclonal TFRC Primary Antibody for FACS - ABIN118800
Sopper, Stahl-Hennig, Demuth, Johnston, Dörries, ter Meulen: Lymphocyte subsets and expression of differentiation markers in blood and lymphoid organs of rhesus monkeys. in Cytometry 1998
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Human Polyclonal TFRC Primary Antibody for IHC (p), WB - ABIN1106545
Enns, Suomalainen, Gebhardt, Schröder, Sussman: Human transferrin receptor: expression of the receptor is assigned to chromosome 3. in Proceedings of the National Academy of Sciences of the United States of America 1982
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Human Polyclonal TFRC Primary Antibody for IHC, ELISA - ABIN1532563
Minami, Otsubo, Ieno, Ikeda, Kanazawa, Shimizu, Ohata, Yokochi, Horii, Fukumoto, Taguchi, Takahashi, Oku, Suzuki: Visualization of sialidase activity in Mammalian tissues and cancer detection with a novel fluorescent sialidase substrate. in PLoS ONE 2014
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Human Monoclonal TFRC Primary Antibody for FACS - ABIN118803
Martel, Aasted: Characterization of antibodies against ferret immunoglobulins, cytokines and CD markers. in Veterinary immunology and immunopathology 2009
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Human Polyclonal TFRC Primary Antibody for IHC, ELISA - ABIN1531548
Evans, Kemp: Exon/intron structure of the human transferrin receptor gene. in Gene 1997
Human Monoclonal TFRC Primary Antibody for FACS - ABIN1106552
Vermot-Desroches, Marchand, Roy, Wijdenes: Heterogeneity of antigen expression among human umbilical cord vascular endothelial cells: identification of cell subsets by co-expression of haemopoietic antigens. in Immunology letters 1996
Human Polyclonal TFRC Primary Antibody for FACS, IHC (p) - ABIN650772
Chicz, Urban, Lane, Gorga, Stern, Vignali, Strominger: Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size. in Nature 1992
Mice lacking Tfr1 in the heart died in the second week of life and had cardiomegaly, poor cardiac function, failure of mitochondrial respiration, and ineffective mitophagy.
Transferrin Receptor 1 (show TFR Antibodies) Facilitates Poliovirus Permeation of Mouse Brain Capillary Endothelial Cells.
Erythrocytic iron deficiency enhances susceptibility to Plasmodium chabaudi infection in mice carrying a missense mutation in tfr1.
Tfr1 has a role in homeostatic maintenance of the intestinal epithelium, acting through a role that is independent of its iron-uptake function
Analysis by qPCR showed changes in mRNA levels of iron-responsive genes, indicating moderately increased iron in the RPE (show RPE Antibodies) of 10-month HID mice.
characterization of erythropoiesis, iron status, and hepcidin (show HAMP Antibodies) expression in mice with global or hematopoietic cell-specific haploinsufficiency of transferrin receptor 1 (show TFR Antibodies) provides initial supporting data for this model
high levels of TfRs such as those found on activated lymphocytes were found to be associated with decreased KLRG1 (show KLRG1 Antibodies) inhibitory function, indicating that TfRs may sequester KLRG1 (show KLRG1 Antibodies) from interacting with cadherins.
data further demonstrate that the inhibitory activity of KLRG1 (show KLRG1 Antibodies) is decreased in T cells expressing high levels of TfR, indicating that association of KLRG1 (show KLRG1 Antibodies) with TfR hinders KLRG1 (show KLRG1 Antibodies)-mediated silencing.
high-affinity anti-TfR alters TfR trafficking, which dramatically impacts the capacity for TfR to mediate blood-brain barrier transcytosis
Data indicate increased levels of reactive oxygen species (ROS (show ROS1 Antibodies)) were detected in bone marrow nucleated cells (BMNC) that express CD71 in in NUP98 (show NUP98 Antibodies)-HOXD13 (show HOXD13 Antibodies) (NHD13) transgenic mice, a murine model for myelodysplastic syndromes (MDS (show MECOM Antibodies)).
Together, our findings reveal that TfR1 can contribute to the mitochondrial respiration and ROS (show ROS1 Antibodies) production, which have essential roles in growth and survival of pancreatic cancer.
siRNA targeted delivery using transferrin (show Tf Antibodies)-coupled lipoplexes specifically sensitizes CD71 high expressing malignant cells to antibody-mediated complement attack
The requirement for a threshold level of TFR1 expression can explain why among primary human hematopoietic cells, only erythroblasts efficiently take up H-ferritin.
Data indicate only the glycoproteins CD34 (show CD34 Antibodies)+/CD71low population showed statistically significant differences between Diamond-Blackfan Anaemia (DBA (show RPS19 Antibodies)) patients and controls.
These results demonstrate that in cells expressing the hTfR, Tacaribe virus internalization depends on the presence of cholesterol, dynamin (show DNM1 Antibodies) and acidic intracellular vesicles.
The importance of TfR1 in adaptive immunity.A missense mutation in TFRC, encoding transferrin receptor 1 (show TFR Antibodies), causes combined immunodeficiency.
The blood levels of TfRC was higher in age-related macular degeneration patients than controls.No association was found between age-related macular degeneration occurrence and the p.Gly142Ser polymorphism of the TRFC gene.
Data show that interleukin 6 (IL-6 (show IL6 Antibodies)) secretion and the percentage of CD71 antigen-positive T lymphocytes both uniquely predicted survival independent of papillomavirus infection status.
Data show that transferrin (show Tf Antibodies) (Tf) was attached to nanoparticles with an acid-cleavable linkage that facilities release of nanoparticles from Tf that are bound to Tf receptors (TfR) during transcytosis, promoting entry of the nanoparticles into the brain.
This study provides insights into the effector functions of human IgG3 in the context of an antibody targeting TfR1.
These data indicate that TfR1 expression in serum exosomes may provide a marker for regeneration in anaemic horses.
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis.
transferrin receptor protein 1
, transferrin receptor (p90, CD71)
, mammary tumor virus receptor 1