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TGFB1I1 encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. Additionally we are shipping TGFB1I1 Proteins (11) and many more products for this protein.
Showing 10 out of 49 products:
Dog (Canine) Monoclonal TGFB1I1 Primary Antibody for IF, WB - ABIN968400
Jia, Ransom, Shibanuma, Liu, Welsh, Smoyer: Identification and characterization of hic-5/ARA55 as an hsp27 binding protein. in The Journal of biological chemistry 2001
Show all 4 references for ABIN968400
Dog (Canine) Polyclonal TGFB1I1 Primary Antibody for IHC, WB - ABIN2780989
Dabiri, Tumbarello, Turner, Van de Water: TGF-beta1 slows the growth of pathogenic myofibroblasts through a mechanism requiring the focal adhesion protein, Hic-5. in The Journal of investigative dermatology 2008
Human Polyclonal TGFB1I1 Primary Antibody for IHC, WB - ABIN2777947
Miyoshi, Ishiguro, Uemura, Fujinami, Miyamoto, Miyoshi, Kitamura, Kubota: Expression of AR associated protein 55 (ARA55) and androgen receptor in prostate cancer. in The Prostate 2003
Hic-5 plays a central role in the positive feedback ROS (show ROS1 Antibodies)-JNK (show MAPK8 Antibodies) signaling cascade that regulates hepatocellular carcinoma progression.
Hic-5 influences the genomic occupancy of multiple steroid receptors and thereby blocks some aspects of hormonal regulation.
Endothelial Hic-5 plays an important role in the formation of microvilli-like structures and in the interaction between ECs and monocytes, leading to monocyte recruitment and subsequent development of atherosclerosis.
Studies in vitro and in vivo using TGF-beta1 (show TGFB1 Antibodies) and TGFB1I1 shRNA demonstrated that TGFB1I1 is required for TGF-beta (show TGFB1 Antibodies) stimulated EMT (show ITK Antibodies) that contributes to malignant progression of astrocytomas.
Hic-5 siRNA also suppressed TGF-beta2 (show TGFB2 Antibodies)-induced fibrogenic activity and dexamethasone-induced myocilin (show MYOC Antibodies) expression in HTM cells.
Hic5 coordinates AR signaling with adhesion and extracellular matrix contacts to regulate cell behavior in the tumor microenvironment.
Hic-5 suppresses senescence and profibrotic activities of myofibroblasts by down-regulating Nox4 (show NOX4 Antibodies) expression.
The ubiquitin ligase activity of Cbl (show CBL Antibodies)-c by the direct interaction of the LIM (show PDLIM5 Antibodies) zinc coordinating domain of Hic5 is demonstrated.
Hic-5 can potentially exercise multiple functions in growth, differentiation, migration and adhesion of keratinocytes, partially via nuclear-cell membrane shuttling.
the HIC-5- and KLF4 (show KLF4 Antibodies)-dependent mechanism transactivates p21(Cip1 (show CDKN1A Antibodies)) in response to anchorage loss
Hic-5 deficiency attenuates the activation of hepatic stellate cells and liver fibrosis though reducing the TGF-beta (show TGFB1 Antibodies)/Smad2 (show SMAD2 Antibodies) signaling by upregulation of Smad7 (show SMAD7 Antibodies)
Hic-5 regulates mesangial cell proliferation in proliferative glomerulonephritis in mice.
Hic-5 is a transcription coregulator that acts before and/or after glucocorticoid receptor (show NR3C1 Antibodies) genome occupancy in a gene-selective manner.
Hic-5 is expressed in B16-F1 murine melanoma cells.
identified Hic-5 as a novel and specific regulatory factor for thrombin (show F2 Antibodies)-induced alphaIIbbeta3 activation and subsequent platelet aggregation in mice.
These data identify discrete roles for paxillin (show PXN Antibodies) and Hic-5 in Rac1 and RhoA (show RHOA Antibodies)-dependent cell adhesion formation and maturation; processes essential for productive cell migration.
Transforming growth factor-beta1-induced transcript 1 protein, a novel marker for smooth muscle contractile phenotype, is regulated by serum response factor/myocardin (show MYOCD Antibodies) protein.
DNA-binding domain acetylation in the TR4 (show NR2C2 Antibodies) nuclear receptor by the coregulator ARA55 leads to suppression of TR4 (show NR2C2 Antibodies) transactivation
This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
transforming growth factor beta 1 induced transcript 1
, androgen receptor coactivator ARA55
, transforming growth factor beta-1-induced transcript 1 protein-like
, androgen receptor coactivator 55 kDa protein
, androgen receptor-associated protein of 55 kDa
, hydrogen peroxide-inducible clone 5 protein
, transforming growth factor beta-1-induced transcript 1 protein
, TGF beta-stimulated clone 5
, androgen receptor activator of 55 kDa