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TRPC4 encodes a member of the canonical subfamily of transient receptor potential cation channels. Additionally we are shipping TRPC4 Proteins (6) and many more products for this protein.
Showing 10 out of 130 products:
Human Polyclonal TRPC4 Primary Antibody for EIA, WB - ABIN955338
Mace, Lussier, Boulay, Terry-Powers, Parfrey, Perraud, Riches: TRUSS, TNF-R1, and TRPC ion channels synergistically reverse endoplasmic reticulum Ca2+ storage reduction in response to m1 muscarinic acetylcholine receptor signaling. in Journal of cellular physiology 2010
Show all 3 references for ABIN955338
Rat (Rattus) Polyclonal TRPC4 Primary Antibody for ELISA, WB - ABIN451705
Song, Zhao, Narcisse, Duffy, Kress, Lee, Brosnan: Canonical transient receptor potential channel 4 (TRPC4) co-localizes with the scaffolding protein ZO-1 in human fetal astrocytes in culture. in Glia 2004
Show all 2 references for ABIN451705
Human Monoclonal TRPC4 Primary Antibody for ICC, IF - ABIN361774
Wu, Huang, Richardson, Priestley, Liu: TRPC4 in rat dorsal root ganglion neurons is increased after nerve injury and is necessary for neurite outgrowth. in The Journal of biological chemistry 2007
Show all 2 references for ABIN361774
Cow (Bovine) Polyclonal TRPC4 Primary Antibody for IHC, WB - ABIN2776213
Odell, Van Helden, Scott: The spectrin cytoskeleton influences the surface expression and activation of human transient receptor potential channel 4 channels. in The Journal of biological chemistry 2008
slow phase of Gi/o-mediated TRPC4 activation was diminished by inhibiting RhoA (show RHOA Antibodies) or enhancing PLCdelta function
Studies indicate potential roles for Rasd1 (show RASD1 Antibodies) small G protein (show RAC2 Antibodies) and leptin (show LEP Antibodies) in TRPC4 cation channel (show TRPV1 Antibodies) activation.
Galpha (show SUCLG1 Antibodies)(i2) activates the TRPC4 channel by direct binding.
This study identifies a novel role for TRPC4 in the regulation of autophagy in vascular endothelial cells.
The higher amplitude of store-operated Ca2 (show CA2 Antibodies)+ entry was associated to the over-expression for Stim2 (show Stim2 Antibodies), Orai2 (show ORAI2 Antibodies)-3, and TRPC1 (show TRPC1 Antibodies) while Stim2 (show Stim2 Antibodies) levels remained constant and Stim1 (show STIM1 Antibodies), Orai1 (show ORAI1 Antibodies), Orai3 (show ORAI3 Antibodies), TRPC1 (show TRPC1 Antibodies) and TRPC4 proteins were over-expressed in primary myelofibrosis.
a membrane-targeting domain of the transient receptor potential canonical (TRPC)4 channel unrelated to its formation of a tetrameric structure
Tarbp2 (show TARBP2 Antibodies) binding to TRPC4 promotes changes of cytosolic Ca(2 (show CA2 Antibodies)+) and, thereby, leads to a dynamic regulation of Dicer (show DICER1 Antibodies) activity, essentially at low endogenous Dicer (show DICER1 Antibodies) concentrations.
the enhanced apoptosis caused by the simultaneous depletion of Dp53 and Dmp52 is absolutely JNK (show MAPK8 Antibodies)-dependent.
the S4-S5 linker is a critical constituent of TRPC4/C5 channel gating and that disturbance of its sequence allows channel opening independent of any sensor domain.
an essential role of Galpha (show SUCLG1 Antibodies)(i) proteins as novel activators for TRPC4/5 and reveal the molecular mechanism by which G-proteins activate the channels.
the antidepressant and anxiolytic-like effects of a newly identified TRPC4/C5 inhibitor, M084.
TRPC4 knockdownsuppressed the activation of ERK (show EPHB2 Antibodies), p38 MAPK (show MAPK14 Antibodies) and AKT (show AKT1 Antibodies) signalingpathway.
Changes in ion selectivity and pore dilation of the TRPC4 channel elicited by the Galphai2 (show GNAI2 Antibodies) subunit, were studied.
Constitutive ablation of TRPC4 in the amygdala is associated with diminished anxiety levels.
Data suggest that TRPC1 (show TRPC1 Antibodies) and TRPC4 are involved in the sprouting of sensory neurons following bladder cystitis, which leads to overactive bladder disease.
Data indicate that kisspeptin activates TRPC4 channels through PIP(2) depletion and cSrc tyrosine kinase activation in GnRH neurons.
The results of this study suggested that TRPC4, TRPM4 (show TRPM4 Antibodies), TRPM8 (show TRPM8 Antibodies) and TRPV1 (show TRPV1 Antibodies), showed statistically significant variation in mRNA levels between DRGs from different segments, suggesting ganglion-specific regulation of TRP (show TYRP1 Antibodies) channel gene expression.
Is unaltered in TRPC5 (show TRPC5 Antibodies) KO mice, but is abolished in TRPC1 (show TRPC1 Antibodies) KO and TRPC1 (show TRPC1 Antibodies)/4 DKO mice.
This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
transient receptor potential 4
, transient receptor potential cation channel, subfamily C, member 5
, transient receptor potential cation channel, subfamily C, member 4
, short transient receptor potential channel 4-like
, short transient receptor potential channel 4
, trp-related protein 4
, capacitative calcium entry channel Trp4
, putative capacitative calcium entry channel
, receptor-activated cation channel TRP4
, transient receptor protein 4
, capacitative calcium entry channel 1
, transient receptor potential channel 4
, transient receptor potential protein 4
, transient receptor potential cation channel TRPC4 middle region 2