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Transmembrane Protein 66 Proteins (TMEM66)

Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. Additionally we are shipping TMEM66 Antibodies (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TMEM66 51669 Q96BY9
TMEM66 67887 Q8R3Q0
TMEM66 290796 Q6AYN2
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Top TMEM66 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,315.50
Details

TMEM66 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Transmembrane Protein 66 (TMEM66) Interaction Partners

Human Transmembrane Protein 66 (TMEM66) interaction partners

  1. SARAF is constitutively expressed in the plasma membrane and interacts with Orai1.

  2. Deletion of STIM1 (show STIM1 Proteins)(448-490) and, in particular, STIM1 (show STIM1 Proteins)(447-460) and STIM1 (show STIM1 Proteins)(475-490) markedly enhances interaction of SARAF with STIM1 (show STIM1 Proteins).

  3. Store-operated Ca2 (show CA2 Proteins)+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients.

  4. Study shows that SARAF is an endoplasmic reticulum resident protein, which responds to cytosolic Ca2 (show CA2 Proteins)+ elevation after ER Ca2 (show CA2 Proteins)+ refilling by promoting a slow inactivation process of STIM2 (show Stim2 Proteins)-dependent basal SOCE activity, as well as STIM1 (show STIM1 Proteins)-mediated SOCE activity.

TMEM66 Protein Profile

Protein Summary

Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (stim1 or stim2)- dependent SOCE activity (By similarity).

Gene names and symbols associated with TMEM66

  • transmembrane protein 66 (TMEM66)
  • zgc:153286 (zgc:153286)
  • transmembrane protein 66 (tmem66)
  • transmembrane protein 66 (MCYG_05410)
  • transmembrane protein 66 (MGYG_06464)
  • transmembrane protein 66 (Tsp_10089)
  • Transmembrane protein 66 (tmm66)
  • transmembrane protein 66 (Tmem66)
  • 1810045K07Rik protein
  • FOAP-7 protein
  • SARAF protein
  • tmem66 protein
  • XTP3 protein

Protein level used designations for TMEM66

transmembrane protein 66 , SOCE-associated regulatory factor , store-operated calcium entry-associated regulatory factor , Transmembrane protein 66 , HBV X-transactivated gene 3 protein , HBV XAg-transactivated protein 3 , SARAF long isoform , SARAF short isoform , protein FOAP-7 , arrestin-E

GENE ID SPECIES
422624 Gallus gallus
464092 Pan troglodytes
482878 Canis lupus familiaris
693452 Macaca mulatta
767649 Danio rerio
779232 Xenopus laevis
9228751 Arthroderma otae CBS 113480
10027179 Arthroderma gypseum CBS 118893
10905752 Trichinella spiralis
100154322 Sus scrofa
100174030 Pongo abelii
100195167 Salmo salar
51669 Homo sapiens
67887 Mus musculus
290796 Rattus norvegicus
515461 Bos taurus
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