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Tripartite Motif Containing 3 Proteins (TRIM3)

The protein encoded by TRIM3 is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. Additionally we are shipping Tripartite Motif Containing 3 Antibodies (68) and Tripartite Motif Containing 3 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRIM3 10612 O75382
TRIM3 55992 Q9R1R2
TRIM3 83616 O70277
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Top Tripartite Motif Containing 3 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,172.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TRIM3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

Rat (Rattus)

More Proteins for Tripartite Motif Containing 3 (TRIM3) Interaction Partners

Human Tripartite Motif Containing 3 (TRIM3) interaction partners

  1. Studies indicate most-studied TRIpartite Motif (TRIM (show TRAT1 Proteins))-NHL proteins TRIM2 (show TRIM2 Proteins), TRIM3, TRIM32 (show TRIM32 Proteins) and TRIM71 (show TRIM71 Proteins), and their mutations have been linked to diseases.

  2. TRIM3 may play a significant role in hepatocellular carcinoma progression.TRIM3 is downregulated in hepatocellular carcinoma at both the mRNA and protein levels and that low TRIM3 expression is correlated with an unfavorable prognosis.

  3. TRIM3 acts as a tumor suppressor in GBM by restoring asymmetric cell division.

  4. Data indicate TRIM3 and p21 (show CDKN1A Proteins) interact in cells.

  5. TRIM63 (show TRIM63 Proteins) is a candidate for genes mediating the glucocorticoid-induced promotion of osteoblastic differentiation.

  6. brain-expressed RING finger protein (BERP) is a gene whose expression is up-regulated in a p53 (show TP53 Proteins)-dependent manner

  7. the endosome-associated protein hrs is a subunit of a protein complex containing actinin-4 (show ACTN4 Proteins), BERP, and myosin V (show MYO5A Proteins) that is necessary for efficient TfR (show TFRC Proteins) recycling but not for EGFR (show EGFR Proteins) degradation

  8. Loss of heterozygosity of chromosome segment 11p15.5 in malignant gliomas suggests TRIM3 as a candidate brain tumor suppressor gene.

Mouse (Murine) Tripartite Motif Containing 3 (TRIM3) interaction partners

  1. Temporal control of gamma-actin (show ACTG1 Proteins) levels by TRIM3 is required to regulate the timing of hippocampal plasticity.

  2. TRIM3, also known as BERP, interacts with KIF21B via its RBCC (show TRIM17 Proteins) domain.

  3. the RING domain is required for TRIM3-induced growth suppression.

  4. Data indicate TRIM3 and p21 interact in cells.

  5. brain-expressed RING finger protein (BERP) is a gene whose expression is up-regulated in a p53 (show TP53 Proteins)-dependent manner

Tripartite Motif Containing 3 (TRIM3) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.

Gene names and symbols associated with TRIM3

  • tripartite motif containing 3 (TRIM3)
  • tripartite motif containing 3 (trim3)
  • tripartite motif-containing 3 (Trim3)
  • Berp protein
  • BERP1 protein
  • HAC1 protein
  • Rnf22 protein
  • RNF97 protein

Protein level used designations for TRIM3

tripartite motif-containing 3 , RING finger protein 97 , brain expressed ring finger , brain-expressed RING finger protein , ring finger protein 22 , tripartite motif protein TRIM3 , tripartite motif-containing protein 3 , RING finger protein HAC1 , tripartite motif protein 3

GENE ID SPECIES
100739484 Sus scrofa
495223 Xenopus laevis
10612 Homo sapiens
476834 Canis lupus familiaris
534510 Bos taurus
55992 Mus musculus
83616 Rattus norvegicus
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