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Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Additionally we are shipping Tryptase delta 1 Proteins (4) and Tryptase delta 1 Kits (3) and many more products for this protein.
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Human Polyclonal TPSD1 Primary Antibody for EIA, IHC (p) - ABIN955305
Jackson, Wang, Bryant, McNeil, Husain, Liu, Tedla, Thomas, King, Hettiaratchi, Cairns, Hunt: Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation. in The Journal of biological chemistry 2008
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Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein.
tryptase delta 1
, serine protease 29
, hmMCP-3-like tryptase III
, mMCP-7-like delta II tryptase
, mast cell tryptase
, tryptase delta