Tumor Necrosis Factor (Ligand) Superfamily, Member 14 Proteins (TNFSF14)

The protein encoded by TNFSF14 is a member of the tumor necrosis factor (TNF) ligand family. Additionally we are shipping TNFSF14 Antibodies (159) and TNFSF14 Kits (32) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNFSF14 8740 O43557
TNFSF14 301133  
TNFSF14 50930 Q9QYH9
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Top TNFSF14 Proteins at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-239), (partial) protein (GST tag) 50 μg Log in to see 13 to 16 Days
$242.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
$704.00
Details
HOST_HEK-293T Human His-DYKDDDDK-Strep II Tag 25 μg Log in to see 11 to 12 Days
$914.29
Details
HOST_Human Cells Human His tag 100 μg Log in to see 20 to 21 Days
$437.80
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details

TNFSF14 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , ,
, , , , , ,
Rat (Rattus)

Mouse (Murine) , ,
,

Top referenced TNFSF14 Proteins

  1. Human TNFSF14 Protein expressed in Escherichia coli (E. coli) - ABIN1047820 : Harrop, McDonnell, Brigham-Burke, Lyn, Minton, Tan, Dede, Spampanato, Silverman, Hensley, DiPrinzio, Emery, Deen, Eichman, Chabot-Fletcher, Truneh, Young: Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth. in The Journal of biological chemistry 1998 (PubMed)
    Show all 2 references for 1047820

More Proteins for Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) Interaction Partners

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) interaction partners

  1. LIGHT is highly expressed and companied with severe inflammations in patients with coronary disease. LIGHT significantly enhanced inflammation response in oxLDL-induced THP-1 macrophages.

  2. LIGHT and LTBR (show LTBR Proteins) interaction increases the survival and proliferation of human bone marrow-derived mesenchymal stem cells, and therefore, LIGHT might play an important role in stem cell therapy.

  3. LIGHT, via LTbetaR signaling, may contribute to exacerbation of airway neutrophilic inflammation through cytokine and chemokine (show CCL1 Proteins) production by bronchial epithelial cells.

  4. LIGHT controls TSLP (show TSLP Proteins) to drive pulmonary fibrosis.

  5. The tumor necrosis factor (show TNF Proteins) superfamily molecule LIGHT promotes keratinocyte activity and skin fibrosis.

  6. proliferation and migration would be enhanced in Tca8113 cells with over-expressed TNFSF14

  7. LIGHT, a TNF (show TNF Proteins) superfamily member, is involved in T-cell homeostasis and erosive bone disease associated with rheumatoid arthritis.

  8. Crystal structures of LIGHT and the LIGHT:DcR3 complex reveal the structural basis for the DcR3 (show TNFRSF6B Proteins)-mediated neutralization of LIGHT.

  9. regulation by NK cell licensing helps to safeguard against TNFSF14 production in response to healthy tissues.

  10. TNFSF14 has an effect on the activation of basophils and eosinophils interacting with bronchial epithelial cells

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) interaction partners

  1. LIGHT signalling pathway combined with IFN-gamma (show IFNG Proteins) induces beta cells apoptosis via an NF-kappaB (show NFKB1 Proteins)/Bcl2 (show BCL2 Proteins)-dependent mitochondrial pathway.

  2. Together, these results demonstrate that the LIGHT signaling pathway is not only required for inflammatory cytokine production as part of the host response to chlamydial infection, but also influences the differentiation of CD4 (show CD4 Proteins)(+) CD25 (show IL2RA Proteins)(+) FoxP3 (show FOXP3 Proteins)(+) Treg cells, both of which may be essential for control of C. psittaci respiratory tract infection.

  3. These results expose the relevance of LIGHT/LTbetaR/HVEM (show TNFRSF14 Proteins) interaction for the potential therapeutic control of the allogeneic immune responses mediated by alloreactive CD8 (show CD8A Proteins) T cells that can contribute to prolong allograft survival.

  4. Mechanistically, intratumoral LIGHT induces pericyte differentiation and normalization via Rho kinase (show ROCK2 Proteins) signaling. Minute amounts of LIGHT act in a paracrine fashion to trigger an amplifying cascade involving transforming growth factor beta (TGF-beta) from peri (show POSTN Proteins)-vascular macrophages.

  5. localized overexpression of Tnfsf14 potently enhances muscle regeneration, and that this regenerative capacity of Tnfsf14 is dependent on Akt (show AKT1 Proteins) signaling.

  6. LIGHT-HVEM (show TNFRSF14 Proteins) interactions stimulate IL-12 (show IL12A Proteins) production by DCs during Leishmania donovani infection. Blockade of LIGHT-LTbetaR interactions dramatically enhanced early anti-parasitic immunity.

  7. LIGHT controls TSLP (show TSLP Proteins) to drive pulmonary fibrosis.

  8. The tumor necrosis factor (show TNF Proteins) superfamily molecule LIGHT promotes keratinocyte activity and skin fibrosis.

  9. Although LIGHT is critical for maintenance of primary Th1 (show HAND1 Proteins) response, it is dispensable during secondary anti-Leishmania immunity in the presence of functional CD40 (show CD40 Proteins) signaling.

  10. LIGHT protein is rapidly and transiently expressed after T-cell activation, and this expression is stronger on CD8 (show CD8A Proteins) T cells than on CD4 (show CD4 Proteins) T cells

TNFSF14 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

Gene names and symbols associated with TNFSF14

  • tumor necrosis factor (ligand) superfamily, member 14 (TNFSF14)
  • tumor necrosis factor (ligand) superfamily, member 14 (Tnfsf14)
  • tumor necrosis factor ligand superfamily, member 14 (LOC100347876)
  • CD258 protein
  • HVEM-L protein
  • HVEML protein
  • LIGHT protein
  • LTg protein
  • Ly113 protein
  • TNFSF14 protein
  • TR2 protein

Protein level used designations for TNFSF14

tumor necrosis factor ligand superfamily, member 14 , tumor necrosis factor (ligand) superfamily, member 14 , delta transmembrane LIGHT , herpes virus entry mediator ligand , herpesvirus entry mediator A , herpesvirus entry mediator ligand , herpesvirus entry mediator-ligand , ligand for herpesvirus entry mediator , tumor necrosis factor ligand superfamily member 14 , tumor necrosis factor receptor-like 2 , tumor necrosis factor superfamily member LIGHT , tumor necrosis factor superfamily member 14 , tumor necrosis factor superfamily, member 14

GENE ID SPECIES
468687 Pan troglodytes
701451 Macaca mulatta
8740 Homo sapiens
301133 Rattus norvegicus
611306 Canis lupus familiaris
100519468 Sus scrofa
505521 Bos taurus
50930 Mus musculus
100347876 Oryctolagus cuniculus
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