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The protein encoded by TNFRSF13B is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. Additionally we are shipping TNFRSF13B Proteins (21) and TNFRSF13B Kits (18) and many more products for this protein.
Showing 10 out of 153 products:
Mouse (Murine) Monoclonal TNFRSF13B Primary Antibody for FACS - ABIN2663250
Ng, Sutherland, Newton, Qian, Cachero, Scott, Thompson, Wheway, Chtanova, Groom, Sutton, Xin, Tangye, Kalled, Mackay, Mackay: B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells. in Journal of immunology (Baltimore, Md. : 1950) 2004
Show all 6 references for ABIN2663250
Human Monoclonal TNFRSF13B Primary Antibody for FACS - ABIN2659695
Bischof, Elsawa, Mantchev, Yoon, Michels, Nilson, Sutor, Platt, Ansell, von Bulow, Bram: Selective activation of TACI by syndecan-2. in Blood 2006
Show all 6 references for ABIN2659695
Human Monoclonal TNFRSF13B Primary Antibody for FACS, ICFC - ABIN2663249
Hymowitz, Patel, Wallweber, Runyon, Yan, Yin, Shriver, Gordon, Pan, Skelton, Kelley, Starovasnik: Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding. in The Journal of biological chemistry 2005
Show all 5 references for ABIN2663249
Human Monoclonal TNFRSF13B Primary Antibody for FACS - ABIN2661017
Yan, Wang, Chan, Roose-Girma, Erickson, Baker, Tumas, Grewal, Dixit: Activation and accumulation of B cells in TACI-deficient mice. in Nature immunology 2001
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Human Polyclonal TNFRSF13B Primary Antibody for WB - ABIN2668579
Sakurai, Hase, Kanno, Kojima, Okumura, Kobata: TACI regulates IgA production by APRIL in collaboration with HSPG. in Blood 2007
SNPs rs9514828 (BAFF (show TNFSF13B Antibodies)), rs3803800 (APRIL) and rs4985726 (TACI) may be associated with the risk of development of B-cell chronic lymphocytic leukemia in a Polish population.
serum levels not associated with disease activity in MPO (show MPO Antibodies)-ANCA-associated renal vasculitis
In this review, we aim at giving an insight into the genetics underlying the CVID and particularly at outlining the role of TACI and its relative contribution to the development of CVID-like phenotypes in human.
TNFRSF13B hemizygosity does not recapitulate autoimmune features of common variable immune deficiency -associated C104R and A181E TNFRSF13B mutations, which likely encode dominant negative products, but instead reveals selective TACI haploinsufficiency at later stages of B-cell development.
Common variable immune d (show TNFSF13B Antibodies)eficiency patients with heterozygous mutations in TACI alleles increase susceptibility to autoimmune diseases.
The study demonstrated that there is a remarkable interindividual variability of TACI expression in chronic lymphocytic leukemia, although the majority of patients display low to undetectable TACI.
Variants of TNFRSF13B were associated with common variable immunodeficiency.
only Transmembrane Activator and CAML Interactor (TACI) correlates with the MMC's capability to ligate BAFF (show TNFSF13B Antibodies). Additionally, the level of expression of TACI correlates with the level of the MMC's BM dependency
Data show significant differences in expression of tumour necrosis factor (show TNF Antibodies) family (BAFF (show TNFSF13B Antibodies)) receptors BAFF-R (show TNFRSF13C Antibodies), BCMA (show TNFRSF17 Antibodies) and TACI in patients with and without anti-Jo-1 or anti-Ro52 (show TRIM21 Antibodies)/anti-Ro60 (show TROVE2 Antibodies) autoantibodies.
Although the transcriptional controls for alternative splicing of TACI isoforms remain unknown, differential signals via isoforms may control plasma-cell generation.
splenic B cells from TACI-deficient (TACI- / -) mice were unable to secrete IL-10 (show IL10 Antibodies) following TLR stimulation, and TACI- / - mice had undetectable basal serum concentrations of IL-10 (show IL10 Antibodies).
Data show that production of autoantibodies in B cell-activating factor (show TNFSF13B Antibodies) of the TNF (show TNF Antibodies) family (BAFF (show TNFSF13B Antibodies)) is dependent on tumor necrosis factor (show TNF Antibodies) receptor superfamily, member 13b protein (TACI) expression by B cells.
Taci (-/-) mice and BAFF (show TNFSF13B Antibodies) transgenic mice both develop signs of human Systemic Lupus Erythematosus.
Elimination of B lymphocyte stimulator (show TNFSF13B Antibodies) receptor 3 (BR-3) and TACI inhibits the development of SLE in NZM mice.
TACI deficiency has a role in alternatively activated macrophage phenotype and susceptibility to Leishmania infection
Heteromers consisting of one BAFF (show TNFSF13B Antibodies) and two APRIL bind to receptor TACI, BCMA (show TNFRSF17 Antibodies) but not to BAFFR (show TNFRSF13C Antibodies).
Mice lacking TACI are able to clear Citrobacter rodentium, a model pathogen for severe human enteritis, more rapidly than did wild type mice.
reduced TACI expression is responsible for the unresponsiveness of XID (show BTK Antibodies) mouse to TI-2 Ags (show GLA Antibodies) and BCR (show BCR Antibodies) activation controls TACI expression.
Although we have found that TACI is dispensable for controlling B. hermsii infection, mice deficient in BAFFR or BAFF exhibit impairment in B. hermsii-specific IgM responses and clearance of bacteremia.
Data indicate that APRIL expression accelerates the onset of TCL1 (show TCL1A Antibodies)-driven leukemia formation mainly through TACI activation.
The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17.
tumor necrosis factor receptor superfamily, member 13B
, tumor necrosis factor receptor superfamily member 13B
, transmembrane activator and CAML interactor
, tumor necrosis factor receptor 13B
, transmembrane activator and calcium-modulating and cyclophilin ligand interactor